TY  - JOUR
TI  - Evaluation of quality of life and its associations with
clinical parameters in pediatric patients with familial
Mediterranean fever
AB  - OBJECTIVE: A favorable quality of life (QoL) is important in children with chronic disease, and it reflects successful disease
management. The aim of our study was to evaluate QoL and its association with clinical parameters in pediatric patients with
familial Mediterranean fever (FMF).
METHODS: The Kinder Lebensqualität Fragebogen (KINDL®) questionnaires (kiddy: 4–7 years; kid: 8–16 years) for children
and the proxy version for parents were implemented as a QoL measure. A total of 171 FMF patients, 69 healthy peers and
their parents were enrolled in the study.
RESULTS: The KINDL QoL scores of the FMF patients were significantly lower than their healthy peers. The physical and
emotional well-being KINDL QoL scores of the FMF children were significantly lower than their healthy peers (p=0.017 and
p=0.020, respectively). In the evaluation of the KINDL QoL scores between the kiddy and kid groups, only the self-esteem
score was higher in the kiddy group (p=0.004), and the school functioning scores were higher in the kid group (p=0.002).
The scores in the physical well-being and disease module had significant differences between patients who were adherent
and those who were non-adherent to colchicine therapy (p=0.042 and p=0.047, respectively). The scores in the physical
well-being and disease module were significantly higher in patients with fewer attacks than those who had many attacks per
year (p=0.004 and p=0.014, respectively).
CONCLUSION: This study suggests that FMF patients have significantly impaired QoL. The irregular use of colchicine and
more frequent attacks affect QoL even more. A QoL assessment with multidisciplinary follow-up and control of the disease
activity are essential, and if necessary, individualized support should be given to patients.
AU  - Çelik, Bülent
AU  - Soysal Acar, Azime Şebnem
AU  - GEZGİN YİLDİRİM, DENİZ
AU  - BAKKALOGLU EZGU, SEVCAN AZIME
AU  - BUYAN, NECLA
DO  - 10.14744/nci.2020.90093
PY  - 2021
JO  - İstanbul Kuzey Klinikleri
VL  - 8
IS  - 3
SN  - 2148-4902
SP  - 255
EP  - 260
DB  - TRDizin
UR  - http://search/yayin/detay/510176
ER  -