TY  - JOUR
TI  - Metastases to the Stomach: Clinicopathologic Features of
Metastases Mimicking Gastric Primaries
AB  - Objective: Metastatic involvement of the stomach is a rare event. Our aim in this study was to document the clinicopathological findings in
patients with gastric metastases and find out if there are any potentially significant features to be used in the differential diagnosis.
Material and Method: Our cohort consisted of 17 histologically verified gastric metastasis cases. Clinical, endoscopic and microscopic features
were retrospectively analyzed.
Results: The primary sites were the breast, skin, lungs, ovaries, colon, and gluteal soft tissue. Three patients were symptomatic because of
the metastatic involvement of the stomach and 9 patients had concomitant metastasis in other sites. Invasive lobular breast carcinoma and
malignant melanoma were the most common metastatic malignancies. The most common macroscopic appearance was the diffuse infiltrative
type (Borrmann Type 4). Most of the metastatic lesions endoscopically mimicked primary gastric cancer. Furthermore, some of the metastatic
lesions, particularly invasive lobular carcinoma of the breast and malignant melanoma, displayed histopathologic features similar to the primary
gastric malignancies to a certain extent.
Conclusion: The possibility of metastatic involvement of stomach must be kept in mind while dealing with a gastric mass lesion in a cancer
patient, even though the clinical and endoscopic features suggest primary gastric cancer. Our study points out the importance of conveying the
information about medical history and clinical findings of the patients for correct pathologic differential diagnosis.
AU  - ÖZGÜR, İlker
AU  - BÜYÜK, Melek
AU  - Gulluoglu, Mine
AU  - AYDIN SUDABATMAZ, ESRA
AU  - Çavuş, Bilger
AU  - VATANSEVER, Sezai
AU  - ALTAY, Ali Yılmaz
AU  - GÖK, Ali Fuat Kaan
DO  - 10.5146/tjpath.2021.01529
PY  - 2021
JO  - Türk Patoloji Dergisi
VL  - 37
IS  - 3
SN  - 1018-5615
SP  - 203
EP  - 211
DB  - TRDizin
UR  - http://search/yayin/detay/510960
ER  -