The Diagnostic Value of Bladder-Wall Thickness and ARFI Elastography of Bladder Wall amongst Patients with BPH
Yıl: 2022 Cilt: 14 Sayı: 1 Sayfa Aralığı: 161 - 167 Metin Dili: İngilizce DOI: 10.18521/ktd.595209 İndeks Tarihi: 29-07-2022
The Diagnostic Value of Bladder-Wall Thickness and ARFI Elastography of Bladder Wall amongst Patients with BPH
Öz: Objective: The present study identified bladder-wall thickness and, through the use of
ARFI elastography, bladder-wall elasticity values amongst patients with benign prostate
hyperplasia (BPH), then examined their relationship with the disease diagnosis and
progression.
Methods: The study included 60 patients with BPH (patient group) and 50 healthy
volunteers (control group). All members of the patient and control groups were measured
for bladder-wall thickness (BWT) and bladder-wall mean shear-wave velocity (BW mean
SWV) values, as well as for uroflowmetry parameters. The patient group was divided
into the sub-groups of mild-medium and severe BPH, according to the International
Prostate Symptom Score (IPSS). The patient and control groups and their sub-groups
were compared amongst themselves.
Results: Whilst the BPH group indicated a mean wall thickness of 6.3±2 mm (range: 3-
12 mm), the control group yielded a result of 2.8±0.7 mm (range: 2-5 mm), which led to
the conclusion that there was a significant difference between these groups (p<0.01). The
BWmeanSWV value was 1.39±0.5 m/s (range: 0.60-2.65 m/s) for the BPH group and
1.01±0.2 m/s (range: 0.60-1.50 m/s) for the control group, and this also indicated the
presence of a significant difference between the groups (p<0.01). According to the IPSS,
BWT was observed to be significantly higher in the severe sub-group when compared to
the mild-medium BPH group [(5.07±1 mm; range: 3-7 mm), (6.8±2 mm; range: 4-12
mm), p<0.01).
Conclusions: When compared to the control group, patients with BPH showed
significantly higher BWT and BWmeanSWV values; these two parameters may provide
an additional method in the diagnosis of bladder outlet obstruction secondary to BPH.
BWT, increasing in parallel with the severity of BPH, may be utilised in the follow-up
for BPH progressionp
Anahtar Kelime: Benin Prostat Hiperplazili Hastalarda Mesane Duvar Kalınlığı ve Mesane Duvar ARFI Elastografinin Tanı Değeri
Öz: Amaç: Çalışmamızda benign prostat hiperplazili (BPH) hastalarda mesane duvar
kalınlığı ve ARFI elastografi yöntemi ile mesane duvarı elastisite değerlerini saptayıp,
hastalığın tanısı ve progresyonu ile ilişkisini araştırdık.
Gereç ve Yöntem: Çalışmaya 60 BPH’lı hasta (Hasta grubu) ile 50 sağlıklı gönüllü
(Kontrol grubu) dahil edildi. Hasta ve kontrol grubunun tamamında mesane duvar
kalınlığı (MDK), mesane duvarı MDmeanSWV değerleri ve uroflovmetre parametreleri
ölçüldü. Hasta grup; International Prostate Symptom Skoru’na (IPSS) göre hafif-orta ve
şiddetli BPH subgruplarına ayrıldı. Hasta–kontrol gurubu ve subgruplar kendi aralarında
karşılaştırıldı.
Bulgular: BPH’lı grup mesane duvar kalınlığı 6.3±2 mm (3-12 mm) iken kontrol
grubunda 2.8±0.7 mm (2-5 mm) olup her iki grup arasında anlamlı fark mevcuttu
(p<0.001). MDmeanSWV değeri BPH’lı grupta 1.39±0.5 m/s (0.60-2.65 m/s) iken,
kontrol grubunda 1.01±0.2 m/s(0.60-1.50) olup her iki grup arasında anlamlı fark
mevcuttu(p<0.001).
IPSS ye göre şiddetli BPH’lı grup, hafif-orta BPH grup ile karşılaştırıldığında MDK,
şiddetli subgrupta anlamlı şekilde daha yüksek bulundu [sırasıyla; 5.07±1 (3-7), 6.8±2 (4-
12), p<0.01].
Sonuç: Kontrol grubuna göre BPH’lı hastalarda MDK ile birlikte MDmeanSWV
elastografi değerleri belirgin yüksektir, bu iki parametre BPH’ya sekonder gelişen
mesane çıkış obstrüksiyon tanısında ilave bir yöntem olabilir. BPH şiddeti ile paralel artış
gösteren MDK, BPH progresyonunun takibinde kullanılabilir.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
- 1. Schoor RA, Canning DA, Bella RD, Broderick GA, Snyder HM 3rd, Duckett JW, et al. Ultrasound diagnosis of bladder outlet obstruction in rabbits. Neurourol Urodyn 1994;13(5):559-69.
- 2. Berry SJ, Coffey DS, Walsh PC, Ewing LL.The development of human benign prostatic hyperplasia with age. J Urol 1984;132(3):474–9.
- 3. Thorpe A, Neal D. Benign prostatic hyperplasia. Lancet 2003;361(9366):1359–67.
- 4. Abrams P. In support of pressure-flow studies for evaluating men with lower urinary tract symptoms. Urology. 1994; 44(2):153-55.
- 5. Reynard JM, Yang Q, Donovan JL, Peters TJ, Schafer W, de la Rosette JJ,Donovan JL, et al. The ICS- ‘‘BPH’’ Study: uroflowmetry, lower urinary tract symptoms and bladder outlet obstruction. Br J Urol 1998;82(5):619–23.
- 6. Botker-Rasmussen I, Bagi P, Balslev Jorgensen J. Is bladder outlet obstruction normal in elderly men without lower urinary tract symptoms? Neurourol Urodyn 1999;18(6):545–52.
- 7. Bright E, Oelke M, Tubaro A, Abrams P. Ultrasound estimated bladder weight and measurement of bladder wall thickness – useful noninvasive methods for assessing the lower urinary tract? J Urol 2010;184(5):1847– 54.
- 8. Hakenberg OW, Linne C, Manseck A, Wirth MP. Bladder wall thickness in normal adults and men with mild lower urinary tract symptoms and benign prostatic enlargement. Neurourol Urodyn 2000; 19(5):585–93.
- 9. Madersbacher S, Alivizatos G, Nordling J, Sanz CR, Emberton M, de la Rosette JJ. EAU 2004 guidelines on assessment, therapy and follow-up of men with lower urinary tract symptoms suggestive of benign prostatic obstruction (BPH guidelines). Eur Urol 2004;46(5):547-54.
- 10. Schulman SL. Voiding dysfunction in children. Urol Clin North Am 2004;31(3): 481-90.
- 11.Jepsen JV, Bruskewitz RC.Urology. Comprehensive patient evaluation for benign prostatic hyperplasia. 1998;51:13-8.
- 12. Homma Y, Gotoh M, Yokoyama O, Masumori N, Kawauchi A, Yamanishi T, et al. Japanese Urological Association. Outline of JUA clinical guidelines for benign prostatic hyperplasia. Int J Urol 2011;18(11):741- 56.
- 13. Nenadic IZ, Qiang B, Urban MW, de Araujo Vasconcelo LH, Nabavizadeh A, Alizad A, et al. Ultrasound bladder vibrometry method for measuring viscoelasticity of the bladder wall.Phys Med Biol 2013 21;58(8):2675-95.
- 14. Korossis S, Bolland F, Ingham E, Fisher J, Kearney J, Southgate J. Review: tissue engineering of the urinary bladder: considering structure-function relationships and the role of mechanotransduction. Tissue Eng 2006;12(4):635-44.
- 15.Cheng HL, Loai Y, Farhat WA. Monitoring tissue development in acellular matrix-based regeneration for bladder tissue engineering: multiexponential diffusion and T2 for improved specificity. NMR Biomed 2012;25(3):418-26.
- 16. Friedrich-Rust M, Nierhoff J, Lupsor M, Sporea I, Fierbinteanu-Braticevici C, Strobel D et al. Performance of Acoustic Radiation Force Impulse imaging for the staging of liver fibrosis: a pooled meta-analysis. J Viral Hepat. 2012;19(2):212–19.
- 17. Myschetzky PS, Suburu RE, Kelly BS Jr, Wilson ML, Chen SC, Lee F. Determination of prostate gland volume by transrectal ultrasound: correlation with radical prostatectomy specimens. Scand J Urol Nephrol Suppl 1991;137:107-11.
- 18. Homma Y, Araki I, Igawa Y, Ozono S, Gotoh M, Yamanishi T, et al; Clinical guideline for male lower urinary tract symptoms. Japanese Society of Neurogenic Bladder.Int J Urol. 2009; 16: 775-90.
- 19. Abrams P, Cardozo L, Fall M, Griffiths D, Rosier P, Ulmsten U et al. The standardization of terminology of lower urinary tract function: report from the Standardization Sub-committee of the International Continence Society. Neurourol Urodyn 2002;21(2):167-78.
- 20. Porru D, Jallous H, Cavalli V, Sallusto F, Rovereto B. Prognostic value of a combination of IPSS, flow rate and residual urine volume compared to pressure-flow studies in the preoperative evaluation of symptomatic BPH. Eur Urol 2002;41(3):246-9.
- 21. Levin RM, Haugaard N, O'Connor L, Buttyan R, Das A, Dixon JS et al. Obstructive response of human bladder to BPH vs. rabbit bladder response to partial outlet obstruction: a direct comparison. Neurourol Urodyn 2000;19(5):609-29.
- 22. Kojima M, Inui E, Ochiai A, Naya Y, Ukimura O, Watanabe H. Ultrasonic estimation of bladder weight as a measure of bladder hypertrophy in men with infravesical obstruction: a preliminary report. Urology 1996;47(6):942-7.
- 23. Kim SO, Song SH, Hwang EC, Oh KJ, Ahn K, Jung SI, et al. Changes in aquaporin (AQP)2 and AQP3 expression in ovariectomized rat urinary bladder: potential implication of water permeability in urinary bladder. World J Urol 2012;30(2):207-12.
- 24. Kessler TM, Gerber R, Burkhard FC, Studer UE, Danuser H. Ultrasound assessment of detrusor thickness in men-can it predict bladder outlet obstruction and replace pressure flow study?. J Urol 2006;175(6):2170-3.
- 25. Salah Azab S, Elsheikh MG. The impact of the bladder wall thickness on the outcome of the medical treatment using alpha-blocker of BPH patients with LUTS. Aging Male 2015; 18(2):89-92.
- 26. Park JS, Lee HW, Lee SW, Moon HS, Park HY, Kim YT. Bladder Wall Thickness is Associated with Responsiveness of Storage Symptoms to Alpha-Blockers in Men with Lower Urinary Tract Symptoms. Korean J Urol 2012;53(7):487-91.
- 27. Elbadawi A, Yalla SV, Resnick NM. Structural basis of geriatric voiding dysfunction. IV. Bladder outlet obstruction. J Urol 1993;150(5 Pt 2):1681-95.
| APA | alan b, göya c, Utanğaç M, Dusak A (2022). The Diagnostic Value of Bladder-Wall Thickness and ARFI Elastography of Bladder Wall amongst Patients with BPH. , 161 - 167. 10.18521/ktd.595209 |
| Chicago | alan bircan,göya cemil,Utanğaç Mehmet mazhar,Dusak Abdurrahim The Diagnostic Value of Bladder-Wall Thickness and ARFI Elastography of Bladder Wall amongst Patients with BPH. (2022): 161 - 167. 10.18521/ktd.595209 |
| MLA | alan bircan,göya cemil,Utanğaç Mehmet mazhar,Dusak Abdurrahim The Diagnostic Value of Bladder-Wall Thickness and ARFI Elastography of Bladder Wall amongst Patients with BPH. , 2022, ss.161 - 167. 10.18521/ktd.595209 |
| AMA | alan b,göya c,Utanğaç M,Dusak A The Diagnostic Value of Bladder-Wall Thickness and ARFI Elastography of Bladder Wall amongst Patients with BPH. . 2022; 161 - 167. 10.18521/ktd.595209 |
| Vancouver | alan b,göya c,Utanğaç M,Dusak A The Diagnostic Value of Bladder-Wall Thickness and ARFI Elastography of Bladder Wall amongst Patients with BPH. . 2022; 161 - 167. 10.18521/ktd.595209 |
| IEEE | alan b,göya c,Utanğaç M,Dusak A "The Diagnostic Value of Bladder-Wall Thickness and ARFI Elastography of Bladder Wall amongst Patients with BPH." , ss.161 - 167, 2022. 10.18521/ktd.595209 |
| ISNAD | alan, bircan vd. "The Diagnostic Value of Bladder-Wall Thickness and ARFI Elastography of Bladder Wall amongst Patients with BPH". (2022), 161-167. https://doi.org/10.18521/ktd.595209 |
| APA | alan b, göya c, Utanğaç M, Dusak A (2022). The Diagnostic Value of Bladder-Wall Thickness and ARFI Elastography of Bladder Wall amongst Patients with BPH. KONURALP TIP DERGİSİ, 14(1), 161 - 167. 10.18521/ktd.595209 |
| Chicago | alan bircan,göya cemil,Utanğaç Mehmet mazhar,Dusak Abdurrahim The Diagnostic Value of Bladder-Wall Thickness and ARFI Elastography of Bladder Wall amongst Patients with BPH. KONURALP TIP DERGİSİ 14, no.1 (2022): 161 - 167. 10.18521/ktd.595209 |
| MLA | alan bircan,göya cemil,Utanğaç Mehmet mazhar,Dusak Abdurrahim The Diagnostic Value of Bladder-Wall Thickness and ARFI Elastography of Bladder Wall amongst Patients with BPH. KONURALP TIP DERGİSİ, vol.14, no.1, 2022, ss.161 - 167. 10.18521/ktd.595209 |
| AMA | alan b,göya c,Utanğaç M,Dusak A The Diagnostic Value of Bladder-Wall Thickness and ARFI Elastography of Bladder Wall amongst Patients with BPH. KONURALP TIP DERGİSİ. 2022; 14(1): 161 - 167. 10.18521/ktd.595209 |
| Vancouver | alan b,göya c,Utanğaç M,Dusak A The Diagnostic Value of Bladder-Wall Thickness and ARFI Elastography of Bladder Wall amongst Patients with BPH. KONURALP TIP DERGİSİ. 2022; 14(1): 161 - 167. 10.18521/ktd.595209 |
| IEEE | alan b,göya c,Utanğaç M,Dusak A "The Diagnostic Value of Bladder-Wall Thickness and ARFI Elastography of Bladder Wall amongst Patients with BPH." KONURALP TIP DERGİSİ, 14, ss.161 - 167, 2022. 10.18521/ktd.595209 |
| ISNAD | alan, bircan vd. "The Diagnostic Value of Bladder-Wall Thickness and ARFI Elastography of Bladder Wall amongst Patients with BPH". KONURALP TIP DERGİSİ 14/1 (2022), 161-167. https://doi.org/10.18521/ktd.595209 |
