Yıl: 2022 Cilt: 24 Sayı: 70 Sayfa Aralığı: 105 - 110 Metin Dili: İngilizce DOI: 10.21205/deufmd.2022247011 İndeks Tarihi: 29-07-2022

Synthesis and Characterization ofNew Series Benzothiazole-Dithiocarbamate Derivatives As Potential Antifungal Agents

Öz:
Invasive fungal infections (IFIs) have been and will continue to be a great threat to human. Nowadays the aim of many medical research is to discover new safer and more effective antifungal agents. Benzothiazole compounds are important fragments in medicinal chemistry because of their wide range of biological activities. Furthermore, dithiocarbamate compounds have become important for many activities due to their chemical structure. In this study, it was aimed to determine being antifungal agents capacity of newly synthesized benzothiazole compounds including dithiocarbamate moiety. The structures of the obtained compounds were elucidated using by 1H-NMR, 13C-NMR and mass spectroscopy.
Anahtar Kelime: Benzothiazole Dithiocarbamate

Potansiyel Antifungal Ajanlar Olarak Yeni Benzotiyazol-Ditiyokarbamat Türevlerinin Sentezi ve Karakterizasyonu

Öz:
İnvaziv mantar enfeksiyonları (IFI'lar) insan için büyük bir tehdit olmuştur ve olmaya devam edecektir. Günümüzde birçok tıbbi araştırmanın amacı yeni daha güvenli ve daha etkili antifungal ajanlar bulmaktır. Benzotiyazol bileşikleri, çok çeşitli biyolojik aktiviteleri nedeniyle farmasötik kimyada önemli bir farmakofor yapıdır. Ayrıca, ditiyokarbamat bileşikleri kimyasal yapıları nedeniyle birçok aktivite için önemli hale gelmiştir. Bu çalışmada, yeni sentezlenen benzotiyazol-ditiyokarbamat bileşiklerinin antifungal etkinliklerinin belirlenmesi amaçlanmıştır. Elde edilen bileşiklerin yapıları, 1H-NMR, 13C-NMR ve kütle spektroskopisi kullanılarak aydınlatılmıştır.
Anahtar Kelime: NMR

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA OSMANİYE D, SAGLIK B (2022). Synthesis and Characterization ofNew Series Benzothiazole-Dithiocarbamate Derivatives As Potential Antifungal Agents. , 105 - 110. 10.21205/deufmd.2022247011
Chicago OSMANİYE DERYA,SAGLIK BEGÜM NURPELIN Synthesis and Characterization ofNew Series Benzothiazole-Dithiocarbamate Derivatives As Potential Antifungal Agents. (2022): 105 - 110. 10.21205/deufmd.2022247011
MLA OSMANİYE DERYA,SAGLIK BEGÜM NURPELIN Synthesis and Characterization ofNew Series Benzothiazole-Dithiocarbamate Derivatives As Potential Antifungal Agents. , 2022, ss.105 - 110. 10.21205/deufmd.2022247011
AMA OSMANİYE D,SAGLIK B Synthesis and Characterization ofNew Series Benzothiazole-Dithiocarbamate Derivatives As Potential Antifungal Agents. . 2022; 105 - 110. 10.21205/deufmd.2022247011
Vancouver OSMANİYE D,SAGLIK B Synthesis and Characterization ofNew Series Benzothiazole-Dithiocarbamate Derivatives As Potential Antifungal Agents. . 2022; 105 - 110. 10.21205/deufmd.2022247011
IEEE OSMANİYE D,SAGLIK B "Synthesis and Characterization ofNew Series Benzothiazole-Dithiocarbamate Derivatives As Potential Antifungal Agents." , ss.105 - 110, 2022. 10.21205/deufmd.2022247011
ISNAD OSMANİYE, DERYA - SAGLIK, BEGÜM NURPELIN. "Synthesis and Characterization ofNew Series Benzothiazole-Dithiocarbamate Derivatives As Potential Antifungal Agents". (2022), 105-110. https://doi.org/10.21205/deufmd.2022247011
APA OSMANİYE D, SAGLIK B (2022). Synthesis and Characterization ofNew Series Benzothiazole-Dithiocarbamate Derivatives As Potential Antifungal Agents. Dokuz Eylül Üniversitesi Mühendislik Fakültesi Fen ve Mühendislik Dergisi, 24(70), 105 - 110. 10.21205/deufmd.2022247011
Chicago OSMANİYE DERYA,SAGLIK BEGÜM NURPELIN Synthesis and Characterization ofNew Series Benzothiazole-Dithiocarbamate Derivatives As Potential Antifungal Agents. Dokuz Eylül Üniversitesi Mühendislik Fakültesi Fen ve Mühendislik Dergisi 24, no.70 (2022): 105 - 110. 10.21205/deufmd.2022247011
MLA OSMANİYE DERYA,SAGLIK BEGÜM NURPELIN Synthesis and Characterization ofNew Series Benzothiazole-Dithiocarbamate Derivatives As Potential Antifungal Agents. Dokuz Eylül Üniversitesi Mühendislik Fakültesi Fen ve Mühendislik Dergisi, vol.24, no.70, 2022, ss.105 - 110. 10.21205/deufmd.2022247011
AMA OSMANİYE D,SAGLIK B Synthesis and Characterization ofNew Series Benzothiazole-Dithiocarbamate Derivatives As Potential Antifungal Agents. Dokuz Eylül Üniversitesi Mühendislik Fakültesi Fen ve Mühendislik Dergisi. 2022; 24(70): 105 - 110. 10.21205/deufmd.2022247011
Vancouver OSMANİYE D,SAGLIK B Synthesis and Characterization ofNew Series Benzothiazole-Dithiocarbamate Derivatives As Potential Antifungal Agents. Dokuz Eylül Üniversitesi Mühendislik Fakültesi Fen ve Mühendislik Dergisi. 2022; 24(70): 105 - 110. 10.21205/deufmd.2022247011
IEEE OSMANİYE D,SAGLIK B "Synthesis and Characterization ofNew Series Benzothiazole-Dithiocarbamate Derivatives As Potential Antifungal Agents." Dokuz Eylül Üniversitesi Mühendislik Fakültesi Fen ve Mühendislik Dergisi, 24, ss.105 - 110, 2022. 10.21205/deufmd.2022247011
ISNAD OSMANİYE, DERYA - SAGLIK, BEGÜM NURPELIN. "Synthesis and Characterization ofNew Series Benzothiazole-Dithiocarbamate Derivatives As Potential Antifungal Agents". Dokuz Eylül Üniversitesi Mühendislik Fakültesi Fen ve Mühendislik Dergisi 24/70 (2022), 105-110. https://doi.org/10.21205/deufmd.2022247011