TY - JOUR TI - Monitoring of oxidative stress and TNF-α status during the healing process in hair goats with metritis AB - Objective: This study aimed to monitor oxidative stress parameters including total antioxidant status (TAS) and total oxidant status (TOS), and tumor necrosis factor-alpha (TNF-α) level during the healing process in hair goats with metritis. Materials and Methods: This study was carried out on a total of 25 hair goats with metritis (n=10; Group 1) and healthy (n=15; Group 2). The beginning of the study was accepted as day 0. In both Group 1 and Group 2, blood samples were collected on days 0 (first measurement day), 14 (second measurement day) and 28 (third measurement day) of the study for TAS, TOS and TNF-α analyzes. In addition, oxidative stress index (OSI) was calculated using TAS and TOS values. Results: It was found that TAS level decreased in Group 1 compared to Group 2 at the first measurement day (p<0.05). However, TOS, OSI and TNF-α levels increased in Group 1 compared to Group 2 (p<0.01). At the second measurement day, TOS and OSI values were higher in Group 1 than Group 2 (p<0.05). Conclusion: In conclusion, the antioxidant system weakened, oxidative stress and TNF-α levels increased in animals with metritis compared to healthy animals. However, at the third measurement time, all parameters became similar between groups. AU - Eski, Funda AU - kurt, serdal AU - mis, leyla DO - 10.47748/tjvr.1069768 PY - 2022 JO - Turkish Journal of Veterinary Research (Online) VL - 6 IS - 1 SN - 2602-3695 SP - 15 EP - 18 DB - TRDizin UR - http://search/yayin/detay/512090 ER -