Yıl: 2021 Cilt: 69 Sayı: 2 Sayfa Aralığı: 125 - 132 Metin Dili: İngilizce DOI: 10.5578/tt.20219801

Evaluation of pulmonary involvement in systemic rheumatic diseases with high resolution computed tomography and pulmonary function test: A single-center experience

Öz:
Evaluation of pulmonary involvement in systemic rheumatic diseases with high resolution computed tomography and pulmonary function test: A single-center experience Introduction: The objective of this study was to investigate the clinical and radiological features and pulmonary function tests (PFTs) in patients with the pulmonary involvement of systemic rheumatic diseases (SRDs). Materials and Methods: This study was conducted as a retrospective and single-center study. Patients diagnosed with an SRD and admitted/referred to the department of chest diseases of our hospital between January 2015 and June 2019 were enrolled. All patients were evaluated using High Resolution Computed Tomography (HRCT) and PFT. Results: This study included 68 patients (15 males, 53 females) with a mean age of 62.38 ± 12.4 years. Forty-one (60.2%) patients had diagnosis of rheumatoid arthritis (RA), 10 (14.7%) patients had sjögren’s syndrome (SS), 8 (11.7%) patients had systemic lupus erythematosus (SLE), 6 (8.8%) patients had systemic sclerosis (SSc), and 3 (4.4%) patients had mixed connective tissue disease (MCTD). While RA, SLE, MCTD patients were more commonly symptomatic, most of the SS patients were asymptomatic. Overall, 30 (44.1%) patients had normal PFT. Although 30 (%44.1) patients were asymptomatic and 30 (%44.1) patients had normal PFTs, at least one imaging finding was found in all patients according to HRCT imaging. “Bronchiectasis” was the most common HRCT finding in RA, followed by “chronic fibrotic changes” and “peribronchial thickening”. “Chronic fibrotic changes” and “peribronchial thickening” were the most common changes in SS. Similarly, “peribronchial thickening” was the most common radiologic finding in SLE. As for SSc, “chronic fibrotic changes”, “interlobular septal thickening”, and “pleural effusion” were the most common radiologic findings. Conclusion: Pulmonary involvement in systemic rheumatic diseases can occur with various radiological images even in asymptomatic patients. PFTs can be normal as well as an obstructive, restrictive or mixed pattern can be seen. Heterogeneous and combined HRCT findings can be seen in SRD patients
Anahtar Kelime:

Konular:
Fen > Tıp > Kulak, Burun, Boğaz
Fen > Tıp > Solunum Sistemi

Sistemik romatizmal hastalıklarda akciğer tutulumunun, yüksek çözünürlüklü bilgisayarlı tomografi ve solunum fonksiyon testi ile değerlendirilmesi: Tek merkez deneyimi

Öz:
Giriş: Bu çalışmanın amacı, sistemik romatizmal hastalıklarda (SRH) akciğer tutulumu olan hastalarda klinik, radyolojik özellikler ve solunum fonksiyon testlerini (SFT) araştırmaktır. Materyal ve Metod: Bu çalışma retrospektif, tanımlayıcı ve tek merkezli olarak gerçekleştirildi. Ocak 2015 - Aralık 2019 yılları arasında SRH tanısı alan ve üçüncü basamak sağlık kurumu olan hastanemiz göğüs hastalıkları bölümüne başvuran/sevk edilen hastalar çalışmaya alındı. Tüm hastalar Yüksek rezolüsyonlu akciğer tomografisi (HRCT) ve SFT kullanılarak değerlendirildi. Bulgular: Çalışmaya ortalama yaşı 62,38 ± 12,4 yıl olan 68 hasta (15 erkek, 53 kadın) dahil edildi. Hastaların 41’inde (%60,2) romatoid artrit (RA), 10’unda (%14,7) sjögren sendromu (SS), 8’inde (%11,7) sistemik lupus eritematozus (SLE), 6’sında (%8,8) sistemik skleroz (SSc) ve 3’ünde (%4,4) mix bağ dokusu hastalığı (MBDH) mevcuttu. RA, SLE, MBDH hastaları genellikle semptomatik iken, SS hastaları genellikle asemptomatikti. Toplam 30 (%44,1) hastada SFT normal olarak değerlendirildi. 30 (%44,1) hasta asemptomatik olduğu halde ve diğer 30 (%44,1) hastada normal SFT bulguları saptanmasına rağmen, HRCT ile tüm hastalarda birden fazla görüntüleme bulgusu saptandı. RA’da en sık görülen HRCT bulgusu “bronşektazi” idi, bunu “kronik fibrotik değişiklikler” ve “peribronşiyal kalınlaşma” izledi. “Kronik fibrotik değişiklikler” ve “peribronşiyal kalınlaşma”, SS’deki en yaygın değişikliklerdi. Benzer şekilde, “peribronşiyal kalınlaşma” SLE’ de en sık görülen HRCT bulgusuydu. SSc’de ise, “kronik fibrotik değişiklikler”, interlobüler septal kalınlaşma ve plevral efüzyon en sık görülen HRCT bulgularıydı. Sonuç: Sistemik romatizmal hastalıklarda pulmoner tutulum, asemptomatik hastalarda dahi çeşitli radyolojik görüntülerle ortaya çıkabilir. SFT normal olabileceği gibi obstruktif, restriktif veya mikst paternde olabilir. Birçok (heterojen) HRCT bulgusu görülebilir
Anahtar Kelime:

Konular:
Fen > Tıp > Kulak, Burun, Boğaz
Fen > Tıp > Solunum Sistemi
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA PAZARLI A, YAKAR H, KÖSEOĞLU H, ÇELİKYAY R, EKİZ T (2021). Evaluation of pulmonary involvement in systemic rheumatic diseases with high resolution computed tomography and pulmonary function test: A single-center experience. Tüberküloz ve Toraks, 69(2), 125 - 132. 10.5578/tt.20219801
Chicago PAZARLI Ahmet Cemal,YAKAR Halil İbrahim,KÖSEOĞLU Handan İnönü,ÇELİKYAY Ruken YÜKSEKKAYA,EKİZ Timur Evaluation of pulmonary involvement in systemic rheumatic diseases with high resolution computed tomography and pulmonary function test: A single-center experience. Tüberküloz ve Toraks 69, no.2 (2021): 125 - 132. 10.5578/tt.20219801
MLA PAZARLI Ahmet Cemal,YAKAR Halil İbrahim,KÖSEOĞLU Handan İnönü,ÇELİKYAY Ruken YÜKSEKKAYA,EKİZ Timur Evaluation of pulmonary involvement in systemic rheumatic diseases with high resolution computed tomography and pulmonary function test: A single-center experience. Tüberküloz ve Toraks, vol.69, no.2, 2021, ss.125 - 132. 10.5578/tt.20219801
AMA PAZARLI A,YAKAR H,KÖSEOĞLU H,ÇELİKYAY R,EKİZ T Evaluation of pulmonary involvement in systemic rheumatic diseases with high resolution computed tomography and pulmonary function test: A single-center experience. Tüberküloz ve Toraks. 2021; 69(2): 125 - 132. 10.5578/tt.20219801
Vancouver PAZARLI A,YAKAR H,KÖSEOĞLU H,ÇELİKYAY R,EKİZ T Evaluation of pulmonary involvement in systemic rheumatic diseases with high resolution computed tomography and pulmonary function test: A single-center experience. Tüberküloz ve Toraks. 2021; 69(2): 125 - 132. 10.5578/tt.20219801
IEEE PAZARLI A,YAKAR H,KÖSEOĞLU H,ÇELİKYAY R,EKİZ T "Evaluation of pulmonary involvement in systemic rheumatic diseases with high resolution computed tomography and pulmonary function test: A single-center experience." Tüberküloz ve Toraks, 69, ss.125 - 132, 2021. 10.5578/tt.20219801