TY  - JOUR
TI  - Aripiprazole-Induced Pulmonary Toxicity in a Patient with Obsessive-Compulsive Disorder
AB  - A 33-year-old male patient with a diagnosis of obsessive-compulsive disorder applied to the emergency department with fever, cough, sputum and increasing shortness of breath. A physical examination revealed the patient to be dyspneic and orthopneic. Bilateral rales were present in middle and basal lung areas. Oxygen saturation in room air was 84%. Diffuse
parenchymal infiltration and consolidation areas were noted in a posteroanterior chest X-ray and a thorax computerized tomography. The patient’s history revealed that the patient used a CPAP machine due to obstructive sleep apnea syndrome and aripiprazole, related to his obsessive-compulsive disorder. The patient was hospitalized in the intensive care unit with a preliminary diagnosis of pneumonia and treated with ceftriaxone 2 gr/day, clarithromycin 2x500 mg and oseltamivir 2x75 mg. Blood and sputum cultures, viral markers and procalcitonin were negative, and so methylprednisolone 40mg/day was started. The patient’s clinical condition improved rapidly after treatment with steroids, and he was discharged on the 8th day after admission, with recommendations for ambulatory care. It was learnt that aripiprazole had been added to his treatment for obsessive-compulsive disorder 1 month earlier, and that his complaints had started and gradually intensified 20 days after this change in medication. The patient’s clinical picture was assessed as lung toxicity caused by aripiprazole.
AU  - DUYGULU, Mustafa Emre
AU  - ALA, Fatme Selen
AU  - TUNA, Tibel
AU  - KÖKSAL, NURHAN
DO  - 10.5505/respircase.2021.10437
PY  - 2021
JO  - Respiratory Case Reports
VL  - 10
IS  - 1
SN  - 2147-2475
SP  - 31
EP  - 35
DB  - TRDizin
UR  - http://search/yayin/detay/512588
ER  -