TY  - JOUR
TI  - Routine Histopathological Examination of the Specimen
After Laparoscopic Cholecystectomy: Can We Be Brave
Enough to Give Up?
AB  - Background: Selective versus routine histopathological examination after cholecystectomy is still in debate. This study aims to investigate
the effect of histopathology results on treatment modality and surgery strategy. The validity of the selective histopathology
approach was questioned.
Methods: The data of patients undergoing laparoscopic cholecystectomy between January 2009 and December 2019 were retrospectively
analyzed. The demographics and histopathology results, whether the operation was emergent or elective, and the reasons for
conversion to open surgery were recorded. Malignant and precursor histopathology diagnoses were examined, and their relationship
with the surgical strategy was questioned.
Results: A total of 2723 patients were included in the study. Of these patients, 2600 (95.5%) were operated under elective, while 123
(4.5%) were operated under emergency conditions. While the surgery was completed laparoscopically in 2685 (98.6%) patients, it was
converted to open surgery in 38 (1.4%) patients. Age, gender, the presence of primary gallbladder cancer, acute cholecystitis, and xanthogranulomatous
cholecystitis in histopathological examination were found to be independent predictive factors for conversion to
open surgery (P < .05). The rate of primary invasive carcinoma in the series was 0.1%.
Conclusion: Routine histopathological examination of the gallbladder is important for demonstrating a wide spectrum of pathological
changes in this organ. Invasive cancer or precursor lesions can be detected even in patients without any macroscopic abnormality.
Histopathological examination also plays a role in determining follow-up, further examination, and treatment modality in addition to
the diagnosis in these patients.
AU  - Leventoglu, Sezai
AU  - KOZAN, Ramazan
AU  - Anadol, Ahmet Ziya
AU  - Karamercan, Ahmet
AU  - Sare, Mustafa
AU  - AYTAÇ, ABDULKADIR BÜLENT
AU  - Özaydın, Safa
AU  - Bayhan, Hüseyin
DO  - 10.5152/tjg.2021.20334
PY  - 2021
JO  - Turkish Journal of Gastroenterology
VL  - 32
IS  - 2
SN  - 1300-4948
SP  - 218
EP  - 224
DB  - TRDizin
UR  - http://search/yayin/detay/513182
ER  -