TY  - JOUR
TI  - The Etiology and Clinical Follow-up of Patients with Acute 
Viral Hepatitis in an Adult Population: A Prospective Multicenter Study
AB  - Objectives: To assess the causes, patient characteristics, clinical 
follow-up of acute viral hepatitis in adults.
Materials and Methods: This prospective study is conducted in 
acute viral hepatitis patients from different centers across Turkey.
Results: From 8 hospitals in 6 provinces, 75 patients (59 males/79%) 
between 20 and 69 years of age (mean age: 34.65±11.82 years) 
with proven viral hepatitis were included into the study. There were 
54 (72%) patients with acute hepatitis B virus (HBV), 19 (25%) 
with acute hepatitis A virus (HAV), 1 (1.3%) with acute Epstein-Barr 
virus, and 1 (1.3%) with acute cytomegalovirus infection. Patients 
between 23-33 years of age represented that greater majority of the 
patient group (41.3%), followed by those between 34 and 43 years 
of age (20%). The mean age among acute HAV patients, i.e. 27±5.7 
years (20-38 y) was significantly (p<0.001) lower than the mean age 
of 37.6±12.2 years (20-69 y) acute HBV group. Of 51 isolated acute 
HBV patients: 44 (86%) developed immunity during the follow up 
[anti-hepatitis B core antibody immunoglobulin G (anti-HBc IgG) and anti-HBs positivity], while isolated anti-HBc IgG positivity persisted 
in 4 patients (8%) and 3 patients (%6) were considered as chronic 
HBV infection due to persistence of hepatitis B surface antigen 
positivity beyond 6 months.
Conclusion: Acute HBV infection remains an important health 
problem in our country, and horizontal and sexual transmission 
became the predominant routes of transmission for HBV. Also, 
acute HAV infection is a prevalent condition in young adults.
AU  - ALBAYRAK, AYŞE
AU  - Tulek, Necla
AU  - olut, ali ılgın
AU  - Ozel, Ayse serra
AU  - Erol, Serpil
AU  - Tosun, Selma
AU  - Ceran, Nurgül
AU  - Dağlı, Özgür
AU  - Kadanalı, Ayten
AU  - Durmuş, Gül
AU  - Altaş, Irem
AU  - ALTUNÇEKİÇ YILDIRIM, ARZU
DO  - 10.4274/vhd.galenos.2021.2021-3-1
PY  - 2021
JO  - Viral Hepatitis Journal
VL  - 27
IS  - 2
SN  - 2147-2939
SP  - 36
EP  - 41
DB  - TRDizin
UR  - http://search/yayin/detay/513913
ER  -