TY  - JOUR
TI  - Unexpected Malignancy Rate of 1630 Hysterectomies
Performed for Benign Indications: A 10-year
Retrospective Analysis
AB  - Hysterectomy is one of the most common operations in gynecology. This study aimed to investigate the
incidence of occult gynecologic malignancies in women undergoing hysterectomy for benign indications.
METHODS
In this retrospective study, the medical records of patients who underwent hysterectomy for benign
indications between 2009-2019 were evaluated using the hospital’s electronic system.
RESULTS
During the study period, 1630 cases underwent hysterectomy for benign indications. The mean age of the
patients was 48.4±6.9 years. The most common indications for hysterectomy were leiomyoma (n=788,
48.3%) and abnormal uterine bleeding (n=539, 33.1%). In the final histopathological evaluation results,
malignancy was identified in 12 cases (0.73%), and the mean age of these cases was 50.41±12 years. These
malignancies included four leiomyosarcomas (33.33%), one endometrial sarcoma (8.33%), two endometrial
adenocarcinomas (16.66%), four ovarian carcinomas (33.33%), and one ovarian fibrosarcoma
(8.33%). Preoperative endometrial sampling was performed in 1160 cases (71.16%). All of the occult malignant
cases had preoperative endometrial sampling and no malignancy was observed in the endometrial
pathology results.
CONCLUSION
Unexpected malignancy rate in women who underwent hysterectomies for benign indications was 0.73%,
and 58.3% of them were related to the uterus, and 41.6% were related to ovarian tissues. Occult uterine
and ovarian malignancies may be observed in hysterectomies performed for benign indications. Detailed
preoperative evaluation is essential to avoid the increased risk of mortality and morbidity caused by late
diagnosis of malignancy.
AU  - AYDIN, Özkan
AU  - GÖKTUĞ KADIOĞLU, Berrin
AU  - ULUĞ, Paşa
AU  - ÖZMEN, Sevilay Akalp
AU  - AKSOY, Ayse Nur
DO  - 10.5505/tjo.2020.2561
PY  - 2021
JO  - Türk Onkoloji Dergisi
VL  - 36
IS  - 2
SN  - 1300-7467
SP  - 171
EP  - 176
DB  - TRDizin
UR  - http://search/yayin/detay/514117
ER  -