Long-term Follow-up of a Toddler with Papillary Thyroid Carcinoma: A Case Report with a Literature Review of Patients Under 5 Years of Age

Yıl: 2022 Cilt: 14 Sayı: 1 Sayfa Aralığı: 119 - 125 Metin Dili: İngilizce DOI: 10.4274/jcrpe.galenos.2020.2020.0178 İndeks Tarihi: 09-06-2022

Long-term Follow-up of a Toddler with Papillary Thyroid Carcinoma: A Case Report with a Literature Review of Patients Under 5 Years of Age

Öz:
Papillary thyroid cancer (PTC) is extremely rare in children. Herein, we present a case diagnosed with PTC at 15 months of age. We conducted a literature review of the published cases with PTC under five years of age. A 1.25-year-old male patient had initially presented with a complaint of progressively enlarging cervical mass that appeared four months earlier. On physical examination, a mass located in the anterior cervical region with the largest measurements of around 3x3 cm was detected. Cervical and thyroid ultrasonography showed a 50x27 mm solid mass in the right lateral neck. Excisional biopsy revealed a follicular variant of PTC with capsular invasion. Subsequently, he underwent a complementary total thyroidectomy. He was diagnosed with intermediate-risk (T3N0M0) PTC. He developed permanent hypoparathyroidism. In the first year of the operation, he was treated with radioiodine ablation (RAI) since basal and stimulated thyroglobulin (Tg) levels tended to increase. Whole-body scintigraphy was normal in the first year of RAI ablation. On levothyroxine sodium (LT4) treatment, levels of thyroid stimulating hormone (TSH) and Tg were adequately suppressed. He is now 8.5-years-old and disease-free on LT4 replacement therapy for seven years and three months. Pediatric PTC has different biological behavior and an excellent prognosis compared to adults. The optimal treatment strategy for pediatric TC is total thyroidectomy, followed by RAI ablation. Post-operative management should include regular follow-up, TSH suppression by adequate LT4 therapy, serial Tg evaluation, and radioiodine scanning when indicated.
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APA Öztürk A, Karakilic-Ozturan E, GUN SOYSAL F, Unal s, ISIK E, Yegen G, Onder S, Yildiz M, Poyrazoglu S, Bas F, Darendeliler F (2022). Long-term Follow-up of a Toddler with Papillary Thyroid Carcinoma: A Case Report with a Literature Review of Patients Under 5 Years of Age. , 119 - 125. 10.4274/jcrpe.galenos.2020.2020.0178
Chicago Öztürk Ayşe Pınar,Karakilic-Ozturan Esin,GUN SOYSAL FERYAL,Unal seher nilgun,ISIK EMINE GOKNUR,Yegen Gulcin,Onder Semen,Yildiz Melek,Poyrazoglu Sukran,Bas Firdevs,Darendeliler Feyza Long-term Follow-up of a Toddler with Papillary Thyroid Carcinoma: A Case Report with a Literature Review of Patients Under 5 Years of Age. (2022): 119 - 125. 10.4274/jcrpe.galenos.2020.2020.0178
MLA Öztürk Ayşe Pınar,Karakilic-Ozturan Esin,GUN SOYSAL FERYAL,Unal seher nilgun,ISIK EMINE GOKNUR,Yegen Gulcin,Onder Semen,Yildiz Melek,Poyrazoglu Sukran,Bas Firdevs,Darendeliler Feyza Long-term Follow-up of a Toddler with Papillary Thyroid Carcinoma: A Case Report with a Literature Review of Patients Under 5 Years of Age. , 2022, ss.119 - 125. 10.4274/jcrpe.galenos.2020.2020.0178
AMA Öztürk A,Karakilic-Ozturan E,GUN SOYSAL F,Unal s,ISIK E,Yegen G,Onder S,Yildiz M,Poyrazoglu S,Bas F,Darendeliler F Long-term Follow-up of a Toddler with Papillary Thyroid Carcinoma: A Case Report with a Literature Review of Patients Under 5 Years of Age. . 2022; 119 - 125. 10.4274/jcrpe.galenos.2020.2020.0178
Vancouver Öztürk A,Karakilic-Ozturan E,GUN SOYSAL F,Unal s,ISIK E,Yegen G,Onder S,Yildiz M,Poyrazoglu S,Bas F,Darendeliler F Long-term Follow-up of a Toddler with Papillary Thyroid Carcinoma: A Case Report with a Literature Review of Patients Under 5 Years of Age. . 2022; 119 - 125. 10.4274/jcrpe.galenos.2020.2020.0178
IEEE Öztürk A,Karakilic-Ozturan E,GUN SOYSAL F,Unal s,ISIK E,Yegen G,Onder S,Yildiz M,Poyrazoglu S,Bas F,Darendeliler F "Long-term Follow-up of a Toddler with Papillary Thyroid Carcinoma: A Case Report with a Literature Review of Patients Under 5 Years of Age." , ss.119 - 125, 2022. 10.4274/jcrpe.galenos.2020.2020.0178
ISNAD Öztürk, Ayşe Pınar vd. "Long-term Follow-up of a Toddler with Papillary Thyroid Carcinoma: A Case Report with a Literature Review of Patients Under 5 Years of Age". (2022), 119-125. https://doi.org/10.4274/jcrpe.galenos.2020.2020.0178
APA Öztürk A, Karakilic-Ozturan E, GUN SOYSAL F, Unal s, ISIK E, Yegen G, Onder S, Yildiz M, Poyrazoglu S, Bas F, Darendeliler F (2022). Long-term Follow-up of a Toddler with Papillary Thyroid Carcinoma: A Case Report with a Literature Review of Patients Under 5 Years of Age. Journal of Clinical Research in Pediatric Endocrinology, 14(1), 119 - 125. 10.4274/jcrpe.galenos.2020.2020.0178
Chicago Öztürk Ayşe Pınar,Karakilic-Ozturan Esin,GUN SOYSAL FERYAL,Unal seher nilgun,ISIK EMINE GOKNUR,Yegen Gulcin,Onder Semen,Yildiz Melek,Poyrazoglu Sukran,Bas Firdevs,Darendeliler Feyza Long-term Follow-up of a Toddler with Papillary Thyroid Carcinoma: A Case Report with a Literature Review of Patients Under 5 Years of Age. Journal of Clinical Research in Pediatric Endocrinology 14, no.1 (2022): 119 - 125. 10.4274/jcrpe.galenos.2020.2020.0178
MLA Öztürk Ayşe Pınar,Karakilic-Ozturan Esin,GUN SOYSAL FERYAL,Unal seher nilgun,ISIK EMINE GOKNUR,Yegen Gulcin,Onder Semen,Yildiz Melek,Poyrazoglu Sukran,Bas Firdevs,Darendeliler Feyza Long-term Follow-up of a Toddler with Papillary Thyroid Carcinoma: A Case Report with a Literature Review of Patients Under 5 Years of Age. Journal of Clinical Research in Pediatric Endocrinology, vol.14, no.1, 2022, ss.119 - 125. 10.4274/jcrpe.galenos.2020.2020.0178
AMA Öztürk A,Karakilic-Ozturan E,GUN SOYSAL F,Unal s,ISIK E,Yegen G,Onder S,Yildiz M,Poyrazoglu S,Bas F,Darendeliler F Long-term Follow-up of a Toddler with Papillary Thyroid Carcinoma: A Case Report with a Literature Review of Patients Under 5 Years of Age. Journal of Clinical Research in Pediatric Endocrinology. 2022; 14(1): 119 - 125. 10.4274/jcrpe.galenos.2020.2020.0178
Vancouver Öztürk A,Karakilic-Ozturan E,GUN SOYSAL F,Unal s,ISIK E,Yegen G,Onder S,Yildiz M,Poyrazoglu S,Bas F,Darendeliler F Long-term Follow-up of a Toddler with Papillary Thyroid Carcinoma: A Case Report with a Literature Review of Patients Under 5 Years of Age. Journal of Clinical Research in Pediatric Endocrinology. 2022; 14(1): 119 - 125. 10.4274/jcrpe.galenos.2020.2020.0178
IEEE Öztürk A,Karakilic-Ozturan E,GUN SOYSAL F,Unal s,ISIK E,Yegen G,Onder S,Yildiz M,Poyrazoglu S,Bas F,Darendeliler F "Long-term Follow-up of a Toddler with Papillary Thyroid Carcinoma: A Case Report with a Literature Review of Patients Under 5 Years of Age." Journal of Clinical Research in Pediatric Endocrinology, 14, ss.119 - 125, 2022. 10.4274/jcrpe.galenos.2020.2020.0178
ISNAD Öztürk, Ayşe Pınar vd. "Long-term Follow-up of a Toddler with Papillary Thyroid Carcinoma: A Case Report with a Literature Review of Patients Under 5 Years of Age". Journal of Clinical Research in Pediatric Endocrinology 14/1 (2022), 119-125. https://doi.org/10.4274/jcrpe.galenos.2020.2020.0178