TY  - JOUR
TI  - Refractory Temporal Lobe Epilepsy in Patients with Mosaic Turner
Syndrome: Two Case Reports and Literature Review
AB  - Turner syndrome (TS) is one of the most common sex chromosome abnormalities
in women, but there are only a few case reports of patients with TS who have
epilepsy or seizures. Here, we report two additional cases with drug‑resistant
temporal lobe epilepsy (TLE) and TS mosaicism. Patient #1 is a 22‑year‑old female
with drug‑resistant TLE whose karyotype analysis showed that 84% of interphase
cells had (45,X) genotype and brain magnetic resonance imaging (MRI) initially
reported as normal showed developmental left temporal lobe encephalocele.
She underwent left temporal lobectomy, and she is seizure free for 10‑year
postoperative follow‑up period. Patient #2 is a 49‑year‑old female who has TLE
with normal brain MRI. The karyotype analysis showed that 2/30 of metaphase
cells had (45, X) genotype. In addition, 11 cases of epilepsy associated with TS
were determined through PubMed. The clinical characteristics of all are reviewed.
AU  - saygi, serap
AU  - ÜTİNE, Eda
AU  - Arslan, Doruk
DO  - 10.4103/nsn.nsn_37_21
PY  - 2021
JO  - Neurological sciences and neurophysiology (Online)
VL  - 38
IS  - 3
SN  - 2636-865X
SP  - 194
EP  - 198
DB  - TRDizin
UR  - http://search/yayin/detay/516960
ER  -