TY  - JOUR
TI  - The Relationship between Early Neurological Deterioration, Poor
Clinical Outcome, and Venous Collateral Score in Cerebral Venous
Sinus Thrombosis
AB  - Background and Purpose: Cerebral venous sinus thrombosis (CVST) is one of
the rare causes of cerebrovascular disease and has an extremely heterogeneous
prognosis. The aim of this study was to investigate the potential relationship
between early neurological deterioration, poor clinical outcome in CVST and
the venous collateral score. Materials and Methods: A total of 121 patients
diagnosed with CVST between 2010 and 2020 were retrospectively included.
The demographic, clinical, and radiological findings related to venous sinus
thrombosis and early neurological deterioration were investigated in relation
to the clinical outcome. Results: The factors associated with early neurological
deterioration were superior sagittal sinus thrombosis (P < 0.001), sinus rectus
thrombosis (P = 0.031), parenchymal lesions (P < 0.001), and venous collateral
score (P < 0.001). The factors associated with poor clinical outcome were superior
sagittal sinus thrombosis (P < 0.001), cortical vein thrombosis (P < 0.001),
venous collateral score (P < 0.001), and initial clinical symptoms. Binary logistic
regression analyses revealed poor clinical outcome as a significant variable,
with a venous collateral scale of 0 or 1 as a risk factor for a poor outcome
(significance of the modelP < 0.001). Conclusion: Early neurologic deterioration
and poor clinical outcome may occur due to poor collateralization in CVST.
Identifying the subgroup of CVST patients at risk of clinical deterioration is
therefore important. This study highlights the clinical importance of venous
collaterals; however, larger prospective multicenter studies are required to confirm
the relationship with venous collaterals in patients with CVST.
AU  - Hakyemez, Bahattin
AU  - Bakar, Mustafa
AU  - DİNÇ, Yasemin
AU  - ÖZPAR, Rıfat
DO  - 10.4103/nsn.nsn_223_20
PY  - 2021
JO  - Neurological sciences and neurophysiology (Online)
VL  - 38
IS  - 3
SN  - 2636-865X
SP  - 158
EP  - 165
DB  - TRDizin
UR  - http://search/yayin/detay/516962
ER  -