TY  - JOUR
TI  - Predictors of postendoscopic retrograde cholangiopancreatography associated
cholangitis: a retrospective cohort study
AB  - Background/aim: Post-ERCP cholangitis (endoscopic retrograde cholangiopancreatography) and associated sepsis can be lifethreatening. Despite the wealth of studies on post-ERCP pancreatitis risk factors, there is limited data on post-ERCP cholangitis. This
study aimed to investigate the rates, predictors, and outcomes of post-ERCP cholangitis.
Materials and methods: A retrospective review of 452 ERCP cases performed by a single endoscopist at a tertiary center between
March 2019 and February 2021 was performed. Patient-related, organizational and periprocedural factors that could affect post-ERCP
cholangitis were evaluated. Predictors of post-ERCP cholangitis were determined by multivariable analysis.
Results: The post-ERCP cholangitis rate was 19.5%. Cholangiocarcinoma (OR 15.72, CI 2.43–101.55, p = 0.004), the American Society
of Anesthesiologist Score (ASA) (OR 2.87, CI 1.14–7.21, p = 0.024), an increase in bilirubin after ERCP (OR 1.81 CI 1.01–3.22, p =
0.043), body mass index (OR 1.15, CI 1.00–1.33, p = 0.04) and procedure duration (OR 1.02, CI 1.00–1.05, p = 0.049) were predictors of
post-ERCP cholangitis. Biliary stone extraction using a balloon was found to be protective against cholangitis (OR 0.18, CI 0.05–0.60, p
= 0.005). Sepsis rate related to post-ERCP cholangitis was 2.4% and death 1%.
Conclusion: Patients who undergo ERCP procedures due to malignant bile duct stenosis, have a high ASA score and BMI, and have a
long procedure time should be paid attention and closely monitored. Further research is needed to determine whether measures aimed
at the identified risk factors will reduce the incidence of post-ERCP.
AU  - Koçyiğit, Burcu
AU  - YILMAZ, HASAN
DO  - 10.3906/sag-2109-84
PY  - 2022
JO  - Turkish Journal of Medical Sciences
VL  - 52
IS  - 1
SN  - 1300-0144
SP  - 105
EP  - 112
DB  - TRDizin
UR  - http://search/yayin/detay/517581
ER  -