TY  - JOUR
TI  - Is Gestational Diabetes Mellitus Associated with the
Metabolic Syndrome?
AB  - Aim: Gestational Diabetes Mellitus (GDM) accounts for 1-14% of
pregnancies. Insulin resistance (IR) plays a role in pathophysiology as it is in Polycystic Ovary Syndrome (PCOS) and Metabolic
Syndrome (MS). Therefore, these three clinical situations are
thought to be related to each other.
Material and Method: In this study, 27 women who were diagnosed with GDM and 30 healthy women were compared in terms
of PCOS, MS and IR.
Results: Weight and body mass index (BMI), waist and hip circumference were higher in the GDM group than in the control group
(respectively 69.0±11,5 kg vs 62.0±10,3 kg, p:0,01; 27.0±4,7 kg/
m2
 vs 23.0±3,5 kg/m2
, p:0,001; 82.0±8,5 cm vs 74.0±7,5 cm,
p<0,001; 103.0±8,1 cm vs 98.0±8,7 cm, p:0,02). MS frequency
was statistically higher in the GDM group than in the control group.
The waist circumference, blood pressure, fasting blood sugar and
triglyceride levels were higher than the control group. (respectively
55,6% vs 20%, p:0,006; 18,5% vs 0%, p:0,01; 29,6% vs 6,7%,
p:0,02; 48,1% vs 10%, p: 0,002). HDL cholesterol levels were
not statistically different between the groups (p> 0.05). When the
threshold for HOMA was taken as 2.24, more insulin resistance
was detected in the GDM group than in the control group (respectively 48,1% vs 20,0%, p: 0,02).
Conclusion: As in GDM, the common problem in MS and PCOS
is IR. As shown in many studies, in our study, MS was found higher in the GDM group. Therefore, metabolic syndrome should be
screened in patients with GDM.
AU  - BULBUL, Mehmet
AU  - Özerkan, Kemal
AU  - Arslan Yıldırım, Emel
AU  - Develioğlu, Osman Haldun
DO  - 10.5505/kjms.2019.87528
PY  - 2019
JO  - Kafkas Tıp Bilimleri Dergisi
VL  - 9
IS  - 2
SN  - 2146-2631
SP  - 110
EP  - 116
DB  - TRDizin
UR  - http://search/yayin/detay/517799
ER  -