Clinically mild encephalitis/encephalopathy with a reversible splenial lesion of the
corpus callosum in childhood: a single-center experience

Yuksel, Deniz; Öztoprak, Ülkühan; özdem, suna; Oguz, Melahat Melek; Derinkuyu, Betul; azapağası, ebru; celik, halil; aksoy, erhan; Ceylan, Nesrin

doi:10.55730/1300-0144.5327

Clinically mild encephalitis/encephalopathy with a reversible splenial lesion of the corpus callosum in childhood: a single-center experience

Halil ÇELİK, (Sağlık Bilimleri Üniversitesi, Dr. Sami Ulus Doğum ve Çocuk Sağlığı ve Hastalıkları Eğitim ve Araştırma Hastanesi, Çocuk Nöroloji Anabilim Dalı, Ankara, Türkiye)

Betül DERİNKUYU, (Sağlık Bilimleri Üniversitesi, Dr.Sami Ulus Doğum ve Çocuk Sağlığı ve Hastalıkları Eğitimi ve Araştırma Hastanesi, Radyoloji Anabilim Dalı, Ankara, Türkiye)

Erhan AKSOY, (Sağlık Bilimleri Üniversitesi, Dr. Sami Ulus Doğum ve Çocuk Sağlığı ve Hastalıkları Eğitim ve Araştırma Hastanesi, Çocuk Nöroloji Anabilim Dalı, Ankara, Türkiye)

Ülkühan ÖZTOPRAK, (Sağlık Bilimleri Üniversitesi, Dr. Sami Ulus Doğum ve Çocuk Sağlığı ve Hastalıkları Eğitim ve Araştırma Hastanesi, Çocuk Nöroloji Anabilim Dalı, Ankara, Türkiye)

Nesrin CEYLAN, (Sağlık Bilimleri Üniversitesi, Dr. Sami Ulus Doğum ve Çocuk Sağlığı ve Hastalıkları Eğitim ve Araştırma Hastanesi, Çocuk Nöroloji Anabilim Dalı, Ankara, Türkiye)

Ebru AZAPAĞASI, (Sağlık Bilimleri Üniversitesi, Dr.Sami Ulus Doğum ve Çocuk Sağlığı ve Hastalıkları Eğitim ve Araştırma Hastanesi, Çocuk Yoğun Bakım Anabilim Dalı, Ankara, Türkiye)

Suna ÖZDEM, (Sağlık Bilimleri Üniversitesi, Dr.Sami Ulus Doğum ve Çocuk Sağlığı ve Hastalıklar Eğitim ve Araştırma Hastanesi, Çocuk Enfeksiyon Hastalıkları Anabilim Dalı, Ankara, Türkiye)

Melahat OĞUZ, (Sağlık Bilimleri Üniversitesi, Dr.Sami Ulus Doğum ve Çocuk Sağlığı ve Hastalıkları Eğitimi ve Araştırma Hastanesi, Çocuk Sağlığı ve Hastalıkları Anabilim Dalı, Ankara, Türkiye)

Deniz YÜKSEL (Sağlık Bilimleri Üniversitesi, Dr. Sami Ulus Doğum ve Çocuk Sağlığı ve Hastalıkları Eğitim ve Araştırma Hastanesi, Çocuk Nöroloji Anabilim Dalı, Ankara, Türkiye)

Turkish Journal of Medical Sciences

2 1

Yıl: 2022 Cilt: 52 Sayı: 2 Sayfa Aralığı: 405 - 412 Metin Dili: İngilizce DOI: 10.55730/1300-0144.5327 İndeks Tarihi: 14-06-2022

Clinically mild encephalitis/encephalopathy with a reversible splenial lesion of the corpus callosum in childhood: a single-center experience

Öz:

Background/aim: Mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) is a rare clinicoradiological syndrome that typically presents with central nervous system symptoms such as loss of consciousness, seizure, headache, and ophthalmoparesis. Materials and methods: Here, we highlight the characteristics of this syndrome together with the clinical and MRI findings of 6 pediatric patients with MERS. Results: Between January 2017 and October 2020, 6 patients with MERS (3 boys and 3 girls) presented to our center. The mean age was 122 ± 54.6 (min-max: 44-180) months. None of the patients had a chronic disease. In our study, infectious agents were detected in 4 patients (66.6%), while noninfectious causes (one seizure and the other hyponatremia) were detected in two patients. All of our cases were discharged without any sequelae after an average of 12.1 ± 7 (min–max: 4–20) days of hospitalization. In 1 patient (case 6), control MRI could not be performed, and the radiological recovery of our other patients was shown to be between 14 days and 2 months. Conclusion: MERS is an acute encephalopathy with good prognosis and should be considered by neurologists in differential diagnosis due to its variable clinical presentation and specific MRI findings.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	celik h, Derinkuyu B, aksoy e, Öztoprak Ü, Ceylan N, azapağası e, özdem s, Oguz M, Yuksel D (2022). Clinically mild encephalitis/encephalopathy with a reversible splenial lesion of the corpus callosum in childhood: a single-center experience. , 405 - 412. 10.55730/1300-0144.5327
Chicago	celik halil,Derinkuyu Betul,aksoy erhan,Öztoprak Ülkühan,Ceylan Nesrin,azapağası ebru,özdem suna,Oguz Melahat Melek,Yuksel Deniz Clinically mild encephalitis/encephalopathy with a reversible splenial lesion of the corpus callosum in childhood: a single-center experience. (2022): 405 - 412. 10.55730/1300-0144.5327
MLA	celik halil,Derinkuyu Betul,aksoy erhan,Öztoprak Ülkühan,Ceylan Nesrin,azapağası ebru,özdem suna,Oguz Melahat Melek,Yuksel Deniz Clinically mild encephalitis/encephalopathy with a reversible splenial lesion of the corpus callosum in childhood: a single-center experience. , 2022, ss.405 - 412. 10.55730/1300-0144.5327
AMA	celik h,Derinkuyu B,aksoy e,Öztoprak Ü,Ceylan N,azapağası e,özdem s,Oguz M,Yuksel D Clinically mild encephalitis/encephalopathy with a reversible splenial lesion of the corpus callosum in childhood: a single-center experience. . 2022; 405 - 412. 10.55730/1300-0144.5327
Vancouver	celik h,Derinkuyu B,aksoy e,Öztoprak Ü,Ceylan N,azapağası e,özdem s,Oguz M,Yuksel D Clinically mild encephalitis/encephalopathy with a reversible splenial lesion of the corpus callosum in childhood: a single-center experience. . 2022; 405 - 412. 10.55730/1300-0144.5327
IEEE	celik h,Derinkuyu B,aksoy e,Öztoprak Ü,Ceylan N,azapağası e,özdem s,Oguz M,Yuksel D "Clinically mild encephalitis/encephalopathy with a reversible splenial lesion of the corpus callosum in childhood: a single-center experience." , ss.405 - 412, 2022. 10.55730/1300-0144.5327
ISNAD	celik, halil vd. "Clinically mild encephalitis/encephalopathy with a reversible splenial lesion of the corpus callosum in childhood: a single-center experience". (2022), 405-412. https://doi.org/10.55730/1300-0144.5327

APA	celik h, Derinkuyu B, aksoy e, Öztoprak Ü, Ceylan N, azapağası e, özdem s, Oguz M, Yuksel D (2022). Clinically mild encephalitis/encephalopathy with a reversible splenial lesion of the corpus callosum in childhood: a single-center experience. Turkish Journal of Medical Sciences, 52(2), 405 - 412. 10.55730/1300-0144.5327
Chicago	celik halil,Derinkuyu Betul,aksoy erhan,Öztoprak Ülkühan,Ceylan Nesrin,azapağası ebru,özdem suna,Oguz Melahat Melek,Yuksel Deniz Clinically mild encephalitis/encephalopathy with a reversible splenial lesion of the corpus callosum in childhood: a single-center experience. Turkish Journal of Medical Sciences 52, no.2 (2022): 405 - 412. 10.55730/1300-0144.5327
MLA	celik halil,Derinkuyu Betul,aksoy erhan,Öztoprak Ülkühan,Ceylan Nesrin,azapağası ebru,özdem suna,Oguz Melahat Melek,Yuksel Deniz Clinically mild encephalitis/encephalopathy with a reversible splenial lesion of the corpus callosum in childhood: a single-center experience. Turkish Journal of Medical Sciences, vol.52, no.2, 2022, ss.405 - 412. 10.55730/1300-0144.5327
AMA	celik h,Derinkuyu B,aksoy e,Öztoprak Ü,Ceylan N,azapağası e,özdem s,Oguz M,Yuksel D Clinically mild encephalitis/encephalopathy with a reversible splenial lesion of the corpus callosum in childhood: a single-center experience. Turkish Journal of Medical Sciences. 2022; 52(2): 405 - 412. 10.55730/1300-0144.5327
Vancouver	celik h,Derinkuyu B,aksoy e,Öztoprak Ü,Ceylan N,azapağası e,özdem s,Oguz M,Yuksel D Clinically mild encephalitis/encephalopathy with a reversible splenial lesion of the corpus callosum in childhood: a single-center experience. Turkish Journal of Medical Sciences. 2022; 52(2): 405 - 412. 10.55730/1300-0144.5327
IEEE	celik h,Derinkuyu B,aksoy e,Öztoprak Ü,Ceylan N,azapağası e,özdem s,Oguz M,Yuksel D "Clinically mild encephalitis/encephalopathy with a reversible splenial lesion of the corpus callosum in childhood: a single-center experience." Turkish Journal of Medical Sciences, 52, ss.405 - 412, 2022. 10.55730/1300-0144.5327
ISNAD	celik, halil vd. "Clinically mild encephalitis/encephalopathy with a reversible splenial lesion of the corpus callosum in childhood: a single-center experience". Turkish Journal of Medical Sciences 52/2 (2022), 405-412. https://doi.org/10.55730/1300-0144.5327