TY  - JOUR
TI  - Clinically mild encephalitis/encephalopathy with a reversible splenial lesion of the
corpus callosum in childhood: a single-center experience
AB  - Background/aim: Mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) is a rare clinicoradiological syndrome
that typically presents with central nervous system symptoms such as loss of consciousness, seizure, headache, and ophthalmoparesis.
Materials and methods: Here, we highlight the characteristics of this syndrome together with the clinical and MRI findings of 6
pediatric patients with MERS.
Results: Between January 2017 and October 2020, 6 patients with MERS (3 boys and 3 girls) presented to our center. The mean age was
122 ± 54.6 (min-max: 44-180) months. None of the patients had a chronic disease. In our study, infectious agents were detected in 4
patients (66.6%), while noninfectious causes (one seizure and the other hyponatremia) were detected in two patients. All of our cases
were discharged without any sequelae after an average of 12.1 ± 7 (min–max: 4–20) days of hospitalization. In 1 patient (case 6), control
MRI could not be performed, and the radiological recovery of our other patients was shown to be between 14 days and 2 months.
Conclusion: MERS is an acute encephalopathy with good prognosis and should be considered by neurologists in differential diagnosis
due to its variable clinical presentation and specific MRI findings.
AU  - Yuksel, Deniz
AU  - Öztoprak, Ülkühan
AU  - özdem, suna
AU  - Oguz, Melahat Melek
AU  - Derinkuyu, Betul
AU  - azapağası, ebru
AU  - celik, halil
AU  - aksoy, erhan
AU  - Ceylan, Nesrin
DO  - 10.55730/1300-0144.5327
PY  - 2022
JO  - Turkish Journal of Medical Sciences
VL  - 52
IS  - 2
SN  - 1300-0144
SP  - 405
EP  - 412
DB  - TRDizin
UR  - http://search/yayin/detay/518119
ER  -