Cost and length of hospital stay for healthcare facility- onset Clostridioides Difficile infection in pediatric wards: a prospective cohort analysis
Yıl: 2021 Cilt: 63 Sayı: 6 Sayfa Aralığı: 1004 - 1011 Metin Dili: İngilizce DOI: 10.24953/turkjped.2021.06.008 İndeks Tarihi: 14-06-2022
Cost and length of hospital stay for healthcare facility- onset Clostridioides Difficile infection in pediatric wards: a prospective cohort analysis
Öz: Background. Clostridioides difficile (C. difficile) is a well-known causative agent of healthcare associated infection,
it increases medical cost besides increasing morbidity and mortality. This study was conducted to determine the
incidence, and economic burden of healthcare facility-onset C. difficile infection (HO-CDI) in children.
Methods. Data was acquired with a prospective cohort study conducted in pediatric wards of a tertiary
university hospital between August 2015 to August 2016. The HO-CDI was defined as diarrhea that began after
48 hours of admission with a positive cytotoxic stool assay for the presence of toxin A and/or B of C. difficile.
Results. In the 3172 admissions in one year, 212 (7%) healthcare associated diarrhea (HAD) episodes were
observed, in 25 (12%) of them C. difficile was identified in which 6 (25%) cases <2-year-old. The incidence of HO-
CDI was estimated as 8.8/10,000 patient-days. Cases with HO-CDI (n=19) were compared with cases with non-
CDI-HAD (n=102); the presence of one of the risk factors for CDI increased the risk for HO-CDI (5,05; 95% Cl:
1.10-23.05; P 0,037), the median length of stay (LOS) attributable HO-CDI was 7 days (IQR,5-10) per admission,
whereas for non-CDI-HAD was 2 days (IQR,0-4) (p=0.036). General hospitalization costs in the two groups
were similar, specifically estimated costs attributable to HO-CDI and non-CID-HAD were $294.0 and $137.0 per
hospitalization respectively (p=<0.0001).
Conclusion. Although in children the incidence of HO-CDI is increasing, its clinical manifestation is still milder
and effective infection control measures with antibiotic stewardship can limit related morbidly, mortality, LOS,
and cost.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA | ÖCAL DEMİR S, KEPENEKLİ E, Akkoc G, Yakut N, Soysal A (2021). Cost and length of hospital stay for healthcare facility- onset Clostridioides Difficile infection in pediatric wards: a prospective cohort analysis. , 1004 - 1011. 10.24953/turkjped.2021.06.008 |
Chicago | ÖCAL DEMİR Sevliya,KEPENEKLİ Eda,Akkoc Gulsen,Yakut Nurhayat,Soysal Ahmet Cost and length of hospital stay for healthcare facility- onset Clostridioides Difficile infection in pediatric wards: a prospective cohort analysis. (2021): 1004 - 1011. 10.24953/turkjped.2021.06.008 |
MLA | ÖCAL DEMİR Sevliya,KEPENEKLİ Eda,Akkoc Gulsen,Yakut Nurhayat,Soysal Ahmet Cost and length of hospital stay for healthcare facility- onset Clostridioides Difficile infection in pediatric wards: a prospective cohort analysis. , 2021, ss.1004 - 1011. 10.24953/turkjped.2021.06.008 |
AMA | ÖCAL DEMİR S,KEPENEKLİ E,Akkoc G,Yakut N,Soysal A Cost and length of hospital stay for healthcare facility- onset Clostridioides Difficile infection in pediatric wards: a prospective cohort analysis. . 2021; 1004 - 1011. 10.24953/turkjped.2021.06.008 |
Vancouver | ÖCAL DEMİR S,KEPENEKLİ E,Akkoc G,Yakut N,Soysal A Cost and length of hospital stay for healthcare facility- onset Clostridioides Difficile infection in pediatric wards: a prospective cohort analysis. . 2021; 1004 - 1011. 10.24953/turkjped.2021.06.008 |
IEEE | ÖCAL DEMİR S,KEPENEKLİ E,Akkoc G,Yakut N,Soysal A "Cost and length of hospital stay for healthcare facility- onset Clostridioides Difficile infection in pediatric wards: a prospective cohort analysis." , ss.1004 - 1011, 2021. 10.24953/turkjped.2021.06.008 |
ISNAD | ÖCAL DEMİR, Sevliya vd. "Cost and length of hospital stay for healthcare facility- onset Clostridioides Difficile infection in pediatric wards: a prospective cohort analysis". (2021), 1004-1011. https://doi.org/10.24953/turkjped.2021.06.008 |
APA | ÖCAL DEMİR S, KEPENEKLİ E, Akkoc G, Yakut N, Soysal A (2021). Cost and length of hospital stay for healthcare facility- onset Clostridioides Difficile infection in pediatric wards: a prospective cohort analysis. Turkish Journal of Pediatrics, 63(6), 1004 - 1011. 10.24953/turkjped.2021.06.008 |
Chicago | ÖCAL DEMİR Sevliya,KEPENEKLİ Eda,Akkoc Gulsen,Yakut Nurhayat,Soysal Ahmet Cost and length of hospital stay for healthcare facility- onset Clostridioides Difficile infection in pediatric wards: a prospective cohort analysis. Turkish Journal of Pediatrics 63, no.6 (2021): 1004 - 1011. 10.24953/turkjped.2021.06.008 |
MLA | ÖCAL DEMİR Sevliya,KEPENEKLİ Eda,Akkoc Gulsen,Yakut Nurhayat,Soysal Ahmet Cost and length of hospital stay for healthcare facility- onset Clostridioides Difficile infection in pediatric wards: a prospective cohort analysis. Turkish Journal of Pediatrics, vol.63, no.6, 2021, ss.1004 - 1011. 10.24953/turkjped.2021.06.008 |
AMA | ÖCAL DEMİR S,KEPENEKLİ E,Akkoc G,Yakut N,Soysal A Cost and length of hospital stay for healthcare facility- onset Clostridioides Difficile infection in pediatric wards: a prospective cohort analysis. Turkish Journal of Pediatrics. 2021; 63(6): 1004 - 1011. 10.24953/turkjped.2021.06.008 |
Vancouver | ÖCAL DEMİR S,KEPENEKLİ E,Akkoc G,Yakut N,Soysal A Cost and length of hospital stay for healthcare facility- onset Clostridioides Difficile infection in pediatric wards: a prospective cohort analysis. Turkish Journal of Pediatrics. 2021; 63(6): 1004 - 1011. 10.24953/turkjped.2021.06.008 |
IEEE | ÖCAL DEMİR S,KEPENEKLİ E,Akkoc G,Yakut N,Soysal A "Cost and length of hospital stay for healthcare facility- onset Clostridioides Difficile infection in pediatric wards: a prospective cohort analysis." Turkish Journal of Pediatrics, 63, ss.1004 - 1011, 2021. 10.24953/turkjped.2021.06.008 |
ISNAD | ÖCAL DEMİR, Sevliya vd. "Cost and length of hospital stay for healthcare facility- onset Clostridioides Difficile infection in pediatric wards: a prospective cohort analysis". Turkish Journal of Pediatrics 63/6 (2021), 1004-1011. https://doi.org/10.24953/turkjped.2021.06.008 |