Yıl: 2021 Cilt: 37 Sayı: 4 Sayfa Aralığı: 213 - 216 Metin Dili: İngilizce DOI: 10.4274/eamr.galenos.2019.65487 İndeks Tarihi: 14-06-2022

Etiological Evaluation of Infants with Wheezing

Öz:
Objective: Patients with recurrent wheezing should be evaluated for asthma and the differential diagnosis should be posed carefully. The study aimed to evaluate the demographic and etiological characteristics of patients presenting with recurrent wheezing less than 3 years. Methods: Ninety‐two children with wheezing were included in this retrospective study at the University of Health Sciences Turkey, Dr. Sami Ulus Maternity Outpatient Clinic, Children’s and Diseases Training and Research Hospital, Ankara, Turkey between March 2009 and March 2010. The demographic characteristics, number of wheezing episodes over the last year, the number of hospitalizations, and eosinophil counts were recorded. Results: The mean age of the participants was 19.9+-9.4 months and the youngest patient was 6 months old. The sample population included seventy (70) boys. The etiologic evaluation of the study population included 42 patients with atopic wheezing, 28 patients with gastroesophageal reflux (GER), and 23 patients with a viral associated wheezing. Eosinophilia was not statistically significant in patients with a family history of atopy (18 patients) related to those with no family history of atopy. Conclusion: In this study, the most prevalent etiological factor was atopy, followed by GER and viral agents, respectively. The definition of children with wheezing includes diseases with different pathophysiology, course, and prognosis. Children with non-atopic wheezing may develop chronic lung inflammation similar to asthma. It is necessary to identify these disorders early enough via monitoring closely and managing adequately. Obtained from the thesis titled, “Is there a diagnostic value of high-sensitivity C-reactive protein in wheezing infants?”.
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  • 1. Martinez FD. Development of wheezing disorders and asthma in preschool children. Pediatrics 2002;109(Suppl 2):362-7.
  • 2. Brand PL, Baraldi E, Bisgaard H, Boner AL, Castro-Rodriguez JA, Custovic A, et al. Definition, assessment and treatment of wheezing disorders in preschool children: an evidence-based approach. Eur Respir J 2008;32:1096-110.
  • 3. Martinez FD. Asthma Phenotypes: Wheezy Infants and Wheezy Children. In: Schwartz RH. et al (eds): Immunology and Allergy Clinics of North America. Philadelphia. WB Saunders. 1998.p.25-34.
  • 4. Ozdogan S, Tabakci B, Demirel AS, Atli B, Besli GE, Kose G. The evaluation of risk factors for recurrent hospitalizations resulting from wheezing attacks in preschool children. Ital J Pediatr 2015;41:91.
  • 5. Worldwide variations in the prevalence of asthma symptoms: the International Study of Asthma and Allergies in Childhood (ISAAC). Eur Respir J 1998;12:315-35.
  • 6. Taussig LM, Wright AL, Holberg CJ, Halonen M, Morgan WJ, Martinez FD. Tucson Children’s Respiratory Study: 1980 to present. J Allergy Clin Immunol 2003;111:661-75; quiz 676.
  • 7. Nakagome K, Nagata M. Pathogenesis of airway inflammation in bronchial asthma. Auris Nasus Larynx 2011;38:555-63.
  • 8. Herr M, Just J, Nikasinovic L, Foucault C, Le Marec AM, Giordanella JP, et al. Risk factors and characteristics of respiratory and allergic phenotypes in early childhood. J Allergy Clin Immunol 2012;130:389-96.e4.
  • 9. İnal A, Güneşer Kendirli S, Ufuk Altıntaş D, Yılmaz M, Karakoç G. The etiology in wheezy infants: data of our patients in a four year period. Turkhis J Pediatr Dis 2009;:24-30.
  • 10. Kilic M, Ozturk F, Kirmemis O, Atmaca S, Guner SN, Caltepe G, et al. Impact of laryngopharyngeal and gastroesophageal reflux on asthma control in children. Int J Pediatr Otorhinolaryngol 2013;77:341-5.
  • 11. Marlow R, Finn A, Henderson J. Assessing the association between bronchiolitis in infancy and recurrent wheeze: a whole English birth cohort case-control study. Thorax 2019;74:503-5.
  • 12. Yu Y, Esther CR Jr, Ren CL, Loughlin C. Persistent wheeze in infants: a guide for general pediatricians. Pediatr Ann 2019;48:e110-e4.
  • 13. Carsin A, Mazenq J, Ilstad A, Dubus JC, Chanez P, Gras D. Bronchial epithelium in children: a key player in asthma. Eur Respir Rev 2016;25:158-69.
  • 14. Saglani S, Payne DN, Zhu J, Wang Z, Nicholson AG, Bush A, et al. Early detection of airway wall remodeling and eosinophilic inflammation in preschool wheezers. Am J Respir Crit Care Med 2007;176:858-64.
  • 15. Turato G, Barbato A, Baraldo S, Zanin ME, Bazzan E, Lokar-Oliani K, et al. Nonatopic children with multitrigger wheezing have airway pathology comparable to atopic asthma. Am J Respir Crit Care Med 2008;178:476- 82.
APA susam sen h, vural ö (2021). Etiological Evaluation of Infants with Wheezing. , 213 - 216. 10.4274/eamr.galenos.2019.65487
Chicago susam sen hilal,vural özge Etiological Evaluation of Infants with Wheezing. (2021): 213 - 216. 10.4274/eamr.galenos.2019.65487
MLA susam sen hilal,vural özge Etiological Evaluation of Infants with Wheezing. , 2021, ss.213 - 216. 10.4274/eamr.galenos.2019.65487
AMA susam sen h,vural ö Etiological Evaluation of Infants with Wheezing. . 2021; 213 - 216. 10.4274/eamr.galenos.2019.65487
Vancouver susam sen h,vural ö Etiological Evaluation of Infants with Wheezing. . 2021; 213 - 216. 10.4274/eamr.galenos.2019.65487
IEEE susam sen h,vural ö "Etiological Evaluation of Infants with Wheezing." , ss.213 - 216, 2021. 10.4274/eamr.galenos.2019.65487
ISNAD susam sen, hilal - vural, özge. "Etiological Evaluation of Infants with Wheezing". (2021), 213-216. https://doi.org/10.4274/eamr.galenos.2019.65487
APA susam sen h, vural ö (2021). Etiological Evaluation of Infants with Wheezing. European Archives of Medical Research, 37(4), 213 - 216. 10.4274/eamr.galenos.2019.65487
Chicago susam sen hilal,vural özge Etiological Evaluation of Infants with Wheezing. European Archives of Medical Research 37, no.4 (2021): 213 - 216. 10.4274/eamr.galenos.2019.65487
MLA susam sen hilal,vural özge Etiological Evaluation of Infants with Wheezing. European Archives of Medical Research, vol.37, no.4, 2021, ss.213 - 216. 10.4274/eamr.galenos.2019.65487
AMA susam sen h,vural ö Etiological Evaluation of Infants with Wheezing. European Archives of Medical Research. 2021; 37(4): 213 - 216. 10.4274/eamr.galenos.2019.65487
Vancouver susam sen h,vural ö Etiological Evaluation of Infants with Wheezing. European Archives of Medical Research. 2021; 37(4): 213 - 216. 10.4274/eamr.galenos.2019.65487
IEEE susam sen h,vural ö "Etiological Evaluation of Infants with Wheezing." European Archives of Medical Research, 37, ss.213 - 216, 2021. 10.4274/eamr.galenos.2019.65487
ISNAD susam sen, hilal - vural, özge. "Etiological Evaluation of Infants with Wheezing". European Archives of Medical Research 37/4 (2021), 213-216. https://doi.org/10.4274/eamr.galenos.2019.65487