TY  - JOUR
TI  - Role of Radiotherapy in Vulvar Squamous Cell Carcinoma: 
Review of the Literature
AB  - En bloc radical vulvectomy with bilateral inguinofemoral lymph node dissection was the standard approach for patients diagnosed with vulvar cancer, regardless of disease extent in the past. This radical surgical approach was with high rates of morbidity and adverse psychological effects and led to 
insufficient locoregional control rates in patients with locally advanced-stage disease. In recent years, 
multimodal treatment approaches have been introduced to decrease treatment-related morbidity and 
increase the locoregional control rates. Radiotherapy (RT) has a major role in the treatment of vulvar 
cancer. It has been successfully used as an adjuvant approach in patients with high risk of local recurrence after surgery and as a sole local treatment with concomitant chemotherapy in locally advanced 
disease. In this current review, we will discuss the rationale of RT and provide up-to-date information 
about the role of RT in the treatment of vulvar cancer.
AU  - Yildiz, Ferah
AU  - Beduk Esen, Caglayan Selenge
AU  - Gultekin, Melis
DO  - 10.5505/tjo.2021.3327
PY  - 2021
JO  - Türk Onkoloji Dergisi
VL  - 36
IS  - 4
SN  - 1300-7467
SP  - 529
EP  - 537
DB  - TRDizin
UR  - http://search/yayin/detay/518972
ER  -