INFLUENZA VACCINATION RATES AND RELATED
FACTORS IN PATIENTS WITH CHRONIC HEART
DISEASE: A CROSS-SECTIONAL STUDY FROM A
TERTIARY HOSPITAL

Şahin, Mustafa Kürşat; Yanik, Ahmet

doi:10.5505/amj.2021.74429

INFLUENZA VACCINATION RATES AND RELATED FACTORS IN PATIENTS WITH CHRONIC HEART DISEASE: A CROSS-SECTIONAL STUDY FROM A TERTIARY HOSPITAL

Ahmet YANIK, (Sağlık Bilimleri Üniversitesi, Samsun Eğitim ve Araştırma Hastanesi, Kardiyoloji Anabilim Dalı, Samsun, Türkiye)

Mustafa Kürşat ŞAHİN (Ondokuz Mayıs Üniversitesi, Tıp Fakültesi, Aile Hekimliği Anabilim Dalı, Samsun, Türkiye)

Ankara Medical Journal

1 0

Yıl: 2021 Cilt: 21 Sayı: 4 Sayfa Aralığı: 619 - 634 Metin Dili: İngilizce DOI: 10.5505/amj.2021.74429 İndeks Tarihi: 15-06-2022

INFLUENZA VACCINATION RATES AND RELATED FACTORS IN PATIENTS WITH CHRONIC HEART DISEASE: A CROSS-SECTIONAL STUDY FROM A TERTIARY HOSPITAL

Öz:

Objectives: Patients with chronic heart disease (CHD) have been defined in many guidelines as one of the priority groups for influenza vaccination. The purpose of this study was to evaluate influenza vaccination rates and related factors in patients with CHD. Materials and Methods: This cross-sectional survey study was conducted between May and August 2019. The questionnaire investigated socio-demographic characteristics, vaccination status in the 2018-19 influenza season, whether the influenza vaccine had been recommended, and vaccine acceptance or refusal reasons. Results: Of the 389 CHD patients participating in the study, 62.21% were male, and 45.24% were aged ≥65. The influenza vaccine uptake rate was 11.31%. Advanced age, vaccination recommendation by a physician, family members living with CHD patients having been previously vaccinated, emergency hospitalization for heart disease or respiratory disease, and knowing that the influenza vaccine was free of charge were factors that increased vaccination acceptance. Conclusion: The influenza vaccination rate among the CHD patients in this study was well below the expected level. The influenza vaccine not being recommended or not sufficiently encouraged, especially by physicians or other healthcare workers, seems to represent the greatest obstacle to influenza vaccination among CHD patients.

Anahtar Kelime:

KRONİK KALP HASTALIĞI OLAN HASTALARDA GRİP AŞISI OLMA ORANLARI VE İLİŞKİLİ FAKTÖRLER: ÜÇÜNCÜ BASAMAK BİR HASTANEDEN KESİTSEL BİR ÇALIŞMA

Öz:

Amaç: Kronik kalp hastalığı (KKH) olan hastalar birçok kılavuzda influenza aşısı için öncelikli gruplardan biri olarak tanımlanmıştır. Bu çalışmanın amacı, KKH'li hastalarda influenza aşılama oranlarını ve ilişkili faktörleri değerlendirmektir. Materyal ve Metot: Bu kesitsel anket çalışması Mayıs-Ağustos 2019 tarihleri arasında yapılmıştır. Ankette sosyo-demografik özellikler, 2018-19 influenza sezonunda aşılanma durumu, influenza aşısının önerilip önerilmediği ve aşı kabul veya ret nedenleri incelenmiştir. Bulgular: Çalışmaya katılan 389 KKH hastasının %62,21'i erkek, %45,24'ü ≥65 yaşındaydı. İnfluenza aşısı olma oranı %11,31 idi. İleri yaş, hekim tarafından aşı önerisi, KKH hastaları ile yaşayan aile bireylerinin daha önce aşılanmış olması, kalp hastalığı veya solunum yolu hastalığı nedeniyle acil yatış ve grip aşısının ücretsiz olduğunun bilinmesi aşı kabulünü artıran faktörlerdi. Sonuç: Bu çalışmada KKH hastalarında influenza aşılama oranı beklenen düzeyin oldukça altındadır. Özellikle doktorlar veya diğer sağlık çalışanları tarafından influenza aşısının tavsiye edilmemesi veya yeterince teşvik edilmemesi, KKH hastaları arasında influenza aşılamasının önündeki en büyük engel olarak görünmektedir.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

1. Iuliano AD, Roguski KM, Chang HH, et al. Estimates of global seasonal influenza-associated respiratory mortality: a modelling study. Lancet. 2018;391(10127):1285-300 (doi:10.1016/S0140-6736(17)33293-2).
2. Rolfes MA, Flannery B, Chung JR, et al. Effects of Influenza Vaccination in the United States During the 2017-2018 Influenza Season. Clin Infect Dis. 2019;69(11):1845-53 (doi:10.1093/cid/ciz075).
3. GBD 2017 Causes of Death Collaborators. Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2018;392(10159):1736-88 (doi:10.1016/S0140-6736(18)32203-7).
4. Vardeny O, Solomon SD. Influenza vaccination: a one-shot deal to reduce cardiovascular events. Eur Heart J. 2017;38(5):334-7 (doi:10.1093/eurheartj/ehw560).
5. Celik A, Altay H, Azap A, et al. Vaccination of adults with heart failure and chronic heart conditions: Expert opinion. Turk Kardiyol Dern A. 2018;46(8):723-34 (doi:10.5543/tkda.2018.10.5543/tkda.2018.37048).
6. Vardeny O, Udell JA, Joseph J, et al. High-dose influenza vaccine to reduce clinical outcomes in high-risk cardiovascular patients: Rationale and design of the INVESTED trial. Am Heart J. 2018;202:97-103 (doi:10.1016/j.ahj.2018.05.007).
7. Ciszewski A. Cardioprotective effect of influenza and pneumococcal vaccination in patients with cardiovascular diseases. Vaccine. 2018;36(2):202-6 (doi:10.1016/j.vaccine.2017.11.078).
8. Vardeny O, Claggett B, Udell JA, et al. Influenza Vaccination in Patients With Chronic Heart Failure: The PARADIGM-HF Trial. Jacc-Heart Fail. 2016;4(2):152-8 (doi:10.1016/j.jchf.2015.10.012).
9. Jorgensen P, Mereckiene J, Cotter S, Johansen K, Tsolova S, Brown C. How close are countries of the WHO European Region to achieving the goal of vaccinating 75% of key risk groups against influenza? Results from national surveys on seasonal influenza vaccination programmes, 2008/2009 to 2014/2015. Vaccine. 2018;36(4):442-52 (doi:10.1016/j.vaccine.2017.12.019).
10. Martinez-Huedo MA, Lopez-De-Andres A, Mora-Zamorano E, et al. Decreasing influenza vaccine coverage among adults with high-risk chronic diseases in Spain from 2014 to 2017. Hum Vacc Immunother. 2020;16(1):95-9 (doi:10.1080/21645515.2019.1646577).
11. Türkiye İstatistik Kurumu. Türkiye Sağlık Araştırması, 2016. 2017 [Internet] https://data.tuik.gov.tr/Bulten/Index?p=Turkiye-Saglik-Arastirmasi-2016-24573#:~:text=Bireylerden%2015%20ya%C5%9F%20ve%20%C3%BCst%C3%BC,oran%C4%B1%20%39%2C7%20oldu. (Accessed: 27.09.2021).
12. Rodrigues BS, David C, Costa J, Ferreira JJ, Pinto FJ, Caldeira D. Influenza vaccination in patients with heart failure: a systematic review and meta-analysis of observational studies. Heart. 2020;106(5):350-7 (doi:10.1136/heartjnl-2019-315193).
13. Vardeny O, Solomon SD. Influenza and Heart Failure: A Catchy Comorbid Combination. Jacc-Heart Fail. 2019;7(2):118-20 (doi:10.1016/j.jchf.2018.11.008).
14. Poudel S, Shehadeh F, Zacharioudakis IM, et al. The Effect of Influenza Vaccination on Mortality and Risk of Hospitalization in Patients With Heart Failure: A Systematic Review and Meta-analysis. Open Forum Infect Di. 2019;6(4):ofz159 (doi:10.1093/ofid/ofz159).
15. Panhwar MS, Kalra A, Gupta T, et al. Effect of Influenza on Outcomes in Patients With Heart Failure. Jacc-Heart Fail. 2019;7(2):112-7 (doi:10.1016/j.jchf.2018.10.011).
16. Sun KS, Lam TP, Kwok KW, Lam KF, Wu D, Ho PL. Seasonal influenza vaccine uptake among Chinese in Hong Kong: barriers, enablers and vaccination rates. Hum Vacc Immunother. 2020;16(7):1675-84 (doi:10.1080/21645515.2019.1709351).
17. Bach AT, Kang AY, Lewis J, Xavioer S, Portillo I, Goad JA. Addressing common barriers in adult immunizations: a review of interventions. Expert Rev Vaccines. 2019;18(11):1167-85 (doi:10.1080/14760584.2019.1698955).
18. Schmid P, Rauber D, Betsch C, Lidolt G, Denker ML. Barriers of Influenza Vaccination Intention and Behavior - A Systematic Review of Influenza Vaccine Hesitancy, 2005 - 2016. PLoS One. 2017;12(1):e0170550 (doi:10.1371/journal.pone.0170550).
19. European Centre for Disease Prevention and Control. Seasonal influenza vaccination and antiviral use in EU/EEA Member States – Overview of vaccine recommendations for 2017–2018 and vaccination coverage rates for 2015–2016 and 2016–2017 influenza seasons. Stockholm: European Centre for Disease Prevention and Control;2018.
20. Sert Karaaslan Y, Yener D. Sağlık Bakanı Koca: Aşımızın devreye girmesi, tahminimiz nisan ayında olur. Anadolu Agency2020.
21. Kim EY, Ko JH, Kim YS, Oh PC. Prevalence and associated factors of influenza vaccination coverage in Korean adults with cardiovascular disease. Medicine (Baltimore). 2020;99(1):e18540 (doi:10.1097/MD.0000000000018540).
22. Wang Y, Cheng M, Wang S, et al. Vaccination coverage with the pneumococcal and influenza vaccine among persons with chronic diseases in Shanghai, China, 2017. BMC Public Health. 2020;20(1):359 (doi:10.1186/s12889-020-8388-3).
23. Olanipekun T, Effoe VS, Olanipekun O, et al. Factors influencing the uptake of influenza vaccination in African American patients with heart failure: Findings from a large urban public hospital. Heart Lung. 2020;49(3):233-7 (doi:10.1016/j.hrtlng.2019.12.003).
24. Fan J, Cong S, Wang N, et al. Influenza vaccination rate and its association with chronic diseases in China: Results of a national cross-sectional study. Vaccine. 2020;38(11):2503-11 (doi:10.1016/j.vaccine.2020.01.093).
25. Bhatt AS, Liang L, DeVore AD, et al. Vaccination Trends in Patients With Heart Failure: Insights From Get With The Guidelines-Heart Failure. Jacc-Heart Fail. 2018;6(10):844-55 (doi:10.1016/j.jchf.2018.04.012).
26. Jang H, Kim JH. Factors affecting influenza vaccination in adults aged 50-64 years with high-risk chronic diseases in South Korea. Hum Vacc Immunother. 2019;15(4):959-66 (doi:10.1080/21645515.2018.1556075).
27. Kizmaz M, Kumtepe Kurt B, Cetin Kargin N, Doner E. Influenza, pneumococcal and herpes zoster vaccination rates among patients over 65 years of age, related factors, and their knowledge and attitudes. Aging Clin Exp Res. 2020;32(11):2383-91 (doi:10.1007/s40520-019-01423-z).
28. Schattner A. Cardiovascular-targeted patient education and uptake of influenza vaccination in elderly patients. Patient Educ Couns. 2020;103(5):1052-4 (doi:10.1016/j.pec.2019.12.008).
29. Peasah SK, Meltzer MI, Vu M, Moulia DL, Bridges CB. Cost-effectiveness of increased influenza vaccination uptake against readmissions of major adverse cardiac events in the US. PLoS One. 2019;14(4):e0213499 (doi:10.1371/journal.pone.0213499).
30. Gleason JL, Jamison A, Freimuth VS, Quinn SC. Home remedy use and influenza vaccination among African American and white adults: An exploratory study. Prev Med. 2019;125:19-23 (doi:10.1016/j.ypmed.2019.05.008).

APA	Yanik A, Şahin M (2021). INFLUENZA VACCINATION RATES AND RELATED FACTORS IN PATIENTS WITH CHRONIC HEART DISEASE: A CROSS-SECTIONAL STUDY FROM A TERTIARY HOSPITAL. , 619 - 634. 10.5505/amj.2021.74429
Chicago	Yanik Ahmet,Şahin Mustafa Kürşat INFLUENZA VACCINATION RATES AND RELATED FACTORS IN PATIENTS WITH CHRONIC HEART DISEASE: A CROSS-SECTIONAL STUDY FROM A TERTIARY HOSPITAL. (2021): 619 - 634. 10.5505/amj.2021.74429
MLA	Yanik Ahmet,Şahin Mustafa Kürşat INFLUENZA VACCINATION RATES AND RELATED FACTORS IN PATIENTS WITH CHRONIC HEART DISEASE: A CROSS-SECTIONAL STUDY FROM A TERTIARY HOSPITAL. , 2021, ss.619 - 634. 10.5505/amj.2021.74429
AMA	Yanik A,Şahin M INFLUENZA VACCINATION RATES AND RELATED FACTORS IN PATIENTS WITH CHRONIC HEART DISEASE: A CROSS-SECTIONAL STUDY FROM A TERTIARY HOSPITAL. . 2021; 619 - 634. 10.5505/amj.2021.74429
Vancouver	Yanik A,Şahin M INFLUENZA VACCINATION RATES AND RELATED FACTORS IN PATIENTS WITH CHRONIC HEART DISEASE: A CROSS-SECTIONAL STUDY FROM A TERTIARY HOSPITAL. . 2021; 619 - 634. 10.5505/amj.2021.74429
IEEE	Yanik A,Şahin M "INFLUENZA VACCINATION RATES AND RELATED FACTORS IN PATIENTS WITH CHRONIC HEART DISEASE: A CROSS-SECTIONAL STUDY FROM A TERTIARY HOSPITAL." , ss.619 - 634, 2021. 10.5505/amj.2021.74429
ISNAD	Yanik, Ahmet - Şahin, Mustafa Kürşat. "INFLUENZA VACCINATION RATES AND RELATED FACTORS IN PATIENTS WITH CHRONIC HEART DISEASE: A CROSS-SECTIONAL STUDY FROM A TERTIARY HOSPITAL". (2021), 619-634. https://doi.org/10.5505/amj.2021.74429

APA	Yanik A, Şahin M (2021). INFLUENZA VACCINATION RATES AND RELATED FACTORS IN PATIENTS WITH CHRONIC HEART DISEASE: A CROSS-SECTIONAL STUDY FROM A TERTIARY HOSPITAL. Ankara Medical Journal, 21(4), 619 - 634. 10.5505/amj.2021.74429
Chicago	Yanik Ahmet,Şahin Mustafa Kürşat INFLUENZA VACCINATION RATES AND RELATED FACTORS IN PATIENTS WITH CHRONIC HEART DISEASE: A CROSS-SECTIONAL STUDY FROM A TERTIARY HOSPITAL. Ankara Medical Journal 21, no.4 (2021): 619 - 634. 10.5505/amj.2021.74429
MLA	Yanik Ahmet,Şahin Mustafa Kürşat INFLUENZA VACCINATION RATES AND RELATED FACTORS IN PATIENTS WITH CHRONIC HEART DISEASE: A CROSS-SECTIONAL STUDY FROM A TERTIARY HOSPITAL. Ankara Medical Journal, vol.21, no.4, 2021, ss.619 - 634. 10.5505/amj.2021.74429
AMA	Yanik A,Şahin M INFLUENZA VACCINATION RATES AND RELATED FACTORS IN PATIENTS WITH CHRONIC HEART DISEASE: A CROSS-SECTIONAL STUDY FROM A TERTIARY HOSPITAL. Ankara Medical Journal. 2021; 21(4): 619 - 634. 10.5505/amj.2021.74429
Vancouver	Yanik A,Şahin M INFLUENZA VACCINATION RATES AND RELATED FACTORS IN PATIENTS WITH CHRONIC HEART DISEASE: A CROSS-SECTIONAL STUDY FROM A TERTIARY HOSPITAL. Ankara Medical Journal. 2021; 21(4): 619 - 634. 10.5505/amj.2021.74429
IEEE	Yanik A,Şahin M "INFLUENZA VACCINATION RATES AND RELATED FACTORS IN PATIENTS WITH CHRONIC HEART DISEASE: A CROSS-SECTIONAL STUDY FROM A TERTIARY HOSPITAL." Ankara Medical Journal, 21, ss.619 - 634, 2021. 10.5505/amj.2021.74429
ISNAD	Yanik, Ahmet - Şahin, Mustafa Kürşat. "INFLUENZA VACCINATION RATES AND RELATED FACTORS IN PATIENTS WITH CHRONIC HEART DISEASE: A CROSS-SECTIONAL STUDY FROM A TERTIARY HOSPITAL". Ankara Medical Journal 21/4 (2021), 619-634. https://doi.org/10.5505/amj.2021.74429