Diagnostic value of diffusion-weighted MRI and conventional MRI in the differentiation of benign and malignant orbital lesions

YETER, VOLKAN; Celenk, Cetin; TANRIVERMIS SAYIT, ASLI; Ozturk, Mesut

doi:10.17826/cumj.994078

Diagnostic value of diffusion-weighted MRI and conventional MRI in the differentiation of benign and malignant orbital lesions

Mesut Öztürk, (Samsun Gazi Devlet Hastanesi, Radyoloji Kliniği, Samsun, Türkiye)

Aslı Tanrıvermiş Sayıt, (Ondokuz Mayıs Üniversitesi, Tıp Fakültesi, Radyoloji Anabilim Dalı, Samsun, Türkiye)

Çetin Çelenk, (Ondokuz Mayıs Üniversitesi, Tıp Fakültesi, Radyoloji Anabilim Dalı, Samsun, Türkiye)

Volkan Yeter (Ondokuz Mayıs Üniversitesi, Tıp Fakültesi, Göz Hastalıkları Anabilim Dalı, Samsun, Türkiye)

Cukurova Medical Journal

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Yıl: 2022 Cilt: 47 Sayı: 1 Sayfa Aralığı: 34 - 43 Metin Dili: İngilizce DOI: 10.17826/cumj.994078 İndeks Tarihi: 29-07-2022

Diagnostic value of diffusion-weighted MRI and conventional MRI in the differentiation of benign and malignant orbital lesions

Öz:

Purpose: The aim of this study was to assess the role of diffusion-weighted imaging (DWI) and conventional magnetic resonance imaging (MRI) in the differentiation of benign and malignant orbital lesions. Materials and Methods: 43 patients (27 women and 16 men; mean age: 26.3±28.5) with orbital lesions were assessed with conventional MRI and DWI. The apparent diffusion coefficient (ADC) of the lesions was measured, and maximum ADC (ADCmax), mean ADC (ADCmean), minimum ADC (ADCmin), the ratio of ADCmean to cerebral white matter ADC (ADCmeanratio), and the ratio of ADCmin to cerebral white matter ADC (ADCminratio) were calculated. T1-weighted and T2-weighted imaging features and contrast enhancement patterns were determined. The diagnostic performances of ADC variables and conventional MRI features for the differentiation of benign and malignant orbital lesions were assessed. Results: ADCmean, ADCmin, ADCmeanratio, and ADCminratio of the malignant lesions were significantly lower than those of the benign ones . ADCmeanratio had the highest diagnostic performance with a sensitivity and specificity of 87.5% and 70.4% at a threshold of 1.27.Selecting a cut-off ADCmean of 0.97 × 10-3 mm2/s for differentiating benign and malignant lesions revealed 75% sensitivity and 74% specificity. Conventional MRI features were not associated with the malignant diagnosis). Conclusion: ADC values obtained from DWI contribute to the differentiation of benign and malignant orbital lesions.

Anahtar Kelime: Diffusion-weighted imaging; apparent diffusion coefficient; orbital neoplasm; magnetic resonance imaging

Benign ve malign orbital lezyonların ayrımında difüzyon ağırlıklı MRG ve konvansiyonel MRG’nin tanısal değeri

Öz:

Amaç: Bu çalışmanın amacı benign ve malign orbital lezyonların ayrımında difüzyon ağırlıklı görüntüleme (DAG) ve konvansiyonel manyetik rezonans görüntüleme (MRG)’nin rolünü değerlendirmektir. Gereç ve Yöntem: Orbital lezyonu 43 hasta (27 kadın ve 16 erkek; ortalama yaş: 26,3 ± 28,5), DAG ve konvansiyonel MRG ile değerlendirildi. Lezyonların görünür difüzyon katsayısı (ADC) ölçüldü ve lezyonların maksimum ADC (ADCmaks), ortalama ADC (ADCort), minimum ADC (ADCmin), ADCort değerinin serebral beyaz cevherin ortalama ADC'sine oranı (ADCortoran) ve ADCmin'in serebral beyaz cevherin ortalama ADC’sine oranı (ADCminoran) hesaplandı. Lezyonların T1 ve T2 ağırlıklı görüntüleme özellikleri ve kontrastlanma paternleri de belirlendi. Malign ve benign orbital lezyonların ayrımı için ADC değişkenlerinin ve konvansiyonel MRG özelliklerinin tanısal performansları değerlendirildi. Bulgular: Malign lezyonların ADCort, ADCmin, ADCortoran ve ADCminoran değerleri, benignlerinkinden anlamlı derecede düşüktü. ADCortoran en yüksek tanısal performansa sahipti; 1,27 sınır değer seçildiğinde duyarlılığı ve özgüllüğü %87,5 ve %70,4 bulundu. Benign ve malign lezyonları ayırt etmek için sınır ADCort değeri 0,97 × 10-3 mm2/s seçilmesi, %75 duyarlılık ve %74 özgüllük ortaya çıkardı. Konvansiyonel MRG özellikleri malign tanı ile ilişkili değildi. Sonuç: DAG'den elde edilen ADC değerleri, benign ve malign orbital lezyonların ayrımına katkı sağlamaktadır.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Ozturk M, TANRIVERMIS SAYIT A, Celenk C, YETER V (2022). Diagnostic value of diffusion-weighted MRI and conventional MRI in the differentiation of benign and malignant orbital lesions. , 34 - 43. 10.17826/cumj.994078
Chicago	Ozturk Mesut,TANRIVERMIS SAYIT ASLI,Celenk Cetin,YETER VOLKAN Diagnostic value of diffusion-weighted MRI and conventional MRI in the differentiation of benign and malignant orbital lesions. (2022): 34 - 43. 10.17826/cumj.994078
MLA	Ozturk Mesut,TANRIVERMIS SAYIT ASLI,Celenk Cetin,YETER VOLKAN Diagnostic value of diffusion-weighted MRI and conventional MRI in the differentiation of benign and malignant orbital lesions. , 2022, ss.34 - 43. 10.17826/cumj.994078
AMA	Ozturk M,TANRIVERMIS SAYIT A,Celenk C,YETER V Diagnostic value of diffusion-weighted MRI and conventional MRI in the differentiation of benign and malignant orbital lesions. . 2022; 34 - 43. 10.17826/cumj.994078
Vancouver	Ozturk M,TANRIVERMIS SAYIT A,Celenk C,YETER V Diagnostic value of diffusion-weighted MRI and conventional MRI in the differentiation of benign and malignant orbital lesions. . 2022; 34 - 43. 10.17826/cumj.994078
IEEE	Ozturk M,TANRIVERMIS SAYIT A,Celenk C,YETER V "Diagnostic value of diffusion-weighted MRI and conventional MRI in the differentiation of benign and malignant orbital lesions." , ss.34 - 43, 2022. 10.17826/cumj.994078
ISNAD	Ozturk, Mesut vd. "Diagnostic value of diffusion-weighted MRI and conventional MRI in the differentiation of benign and malignant orbital lesions". (2022), 34-43. https://doi.org/10.17826/cumj.994078

APA	Ozturk M, TANRIVERMIS SAYIT A, Celenk C, YETER V (2022). Diagnostic value of diffusion-weighted MRI and conventional MRI in the differentiation of benign and malignant orbital lesions. Cukurova Medical Journal, 47(1), 34 - 43. 10.17826/cumj.994078
Chicago	Ozturk Mesut,TANRIVERMIS SAYIT ASLI,Celenk Cetin,YETER VOLKAN Diagnostic value of diffusion-weighted MRI and conventional MRI in the differentiation of benign and malignant orbital lesions. Cukurova Medical Journal 47, no.1 (2022): 34 - 43. 10.17826/cumj.994078
MLA	Ozturk Mesut,TANRIVERMIS SAYIT ASLI,Celenk Cetin,YETER VOLKAN Diagnostic value of diffusion-weighted MRI and conventional MRI in the differentiation of benign and malignant orbital lesions. Cukurova Medical Journal, vol.47, no.1, 2022, ss.34 - 43. 10.17826/cumj.994078
AMA	Ozturk M,TANRIVERMIS SAYIT A,Celenk C,YETER V Diagnostic value of diffusion-weighted MRI and conventional MRI in the differentiation of benign and malignant orbital lesions. Cukurova Medical Journal. 2022; 47(1): 34 - 43. 10.17826/cumj.994078
Vancouver	Ozturk M,TANRIVERMIS SAYIT A,Celenk C,YETER V Diagnostic value of diffusion-weighted MRI and conventional MRI in the differentiation of benign and malignant orbital lesions. Cukurova Medical Journal. 2022; 47(1): 34 - 43. 10.17826/cumj.994078
IEEE	Ozturk M,TANRIVERMIS SAYIT A,Celenk C,YETER V "Diagnostic value of diffusion-weighted MRI and conventional MRI in the differentiation of benign and malignant orbital lesions." Cukurova Medical Journal, 47, ss.34 - 43, 2022. 10.17826/cumj.994078
ISNAD	Ozturk, Mesut vd. "Diagnostic value of diffusion-weighted MRI and conventional MRI in the differentiation of benign and malignant orbital lesions". Cukurova Medical Journal 47/1 (2022), 34-43. https://doi.org/10.17826/cumj.994078