TY  - JOUR
TI  - Evaluation of neuropsychiatric symptoms in patients with multiple sclerosis
AB  - Purpose: The aim of this study was to comprehensively assess the neurophyschiatric symptoms of multiple sclerosis (MS) such as apathy and pseudobulbar affect and their correlation with other concomitant factors.
Materials and Methods: Montreal Cognitive Assessment (MoCA), Apathy Evaluation Scale (AES), Fatigue severity scale (FSS), Center for Neurologic Study-Lability Scale (CNS-LS), Beck Depression Inventory (BDI) are applied to 258 MS patients. Correlation and regression analysis are conducted between scales and other possible causers.
Results: 53.6% of the patients have psuedobulbar affect, 76.2% of patient population have fatigue. Pseudobulbar affect had positive correlation with fatigue and also depression while apathy negatively correlate with pseudobulbar affect or fatigue. Additionally, apathy and depression correlated negatively. There was no relation between cognition and depression and/or disease duration and/or other scales’ scores. 
Conclusion: Pseudobulbar affect and apathy are quite common symptoms in MS patients, that are cross-cutting issues. Also, apathy may be an independent neuropyschiatric symptom of MS that need to be approached separately.
AU  - totuk, ozlem
AU  - gungor dogan, ipek
AU  - CELİK, Didem Celik
AU  - Demir, Serkan
AU  - Gonul, Ozge
DO  - 10.17826/cumj.1018632
PY  - 2022
JO  - Cukurova Medical Journal
VL  - 47
IS  - 1
SN  - 2602-3032
SP  - 208
EP  - 218
DB  - TRDizin
UR  - http://search/yayin/detay/519923
ER  -