Are mucocutaneous lesions seasonal in Behçet's disease?
Yıl: 2022 Cilt: 47 Sayı: 1 Sayfa Aralığı: 16 - 20 Metin Dili: İngilizce DOI: 10.17826/cumj.980169 İndeks Tarihi: 29-07-2022
Are mucocutaneous lesions seasonal in Behçet's disease?
Öz: Purpose: Although it is worth to investigate seasonality in a disease that has a recurrent course, this issue has not been dealt with sufficiently for Behçet’s disease. The aim of the study was to evaluate whether or not frequencies of its mucocutaneous attacks varied between months of the year.
Materials and Methods: One hundred eight patients with Behçet’s disease were retrospectively evaluated in terms of attacks of oral aphthae, genital ulcers, and erythema nodosum. For their each visit, a four-week period preceded this visit and dates of attack onsets in this period were taken into consideration. Then, by using them, mean monthly attack numbers were calculated for time series analysis.
Results: Although mean monthly attack numbers were higher in May and October for oral aphthae and in August for genital ulcers, seasonalities were not verified by time series analysis.
Conclusion: After a literature search on PubMed, there is only one study that detected no seasonality for mucocutaneous lesions of Behçet’s disease, and only one study detected a seasonality for oral aphthae. However, it is worth noting that time series analysis is not utilized in these studies. Since the present study is retrospective, its results should be verified by diary-based prospective studies that include time series analysis.
Anahtar Kelime: Behçet hastalığında mukokutanöz lezyonlar mevsimsel midir?
Öz: Amaç: Tekrarlayan seyir gösteren bir hastalıkta mevsimsellik araştırılmaya değer olmakla birlikte Behçet hastalığında yeterince ele alınmamıştır. Çalışmanın amacı, mukokutanöz atakların sıklığının aylar arasında farklılık gösterip göstermediğini değerlendirmektir.
Gereç ve Yöntem: Behçet hastalığı olan 108 hasta oral aft, genital ülser ve eritema nodozum atakları açısından retrospektif olarak değerlendirildi. Hastaların her vizitinde, bu vizit öncesindeki dört haftalık süre ve bu sürede atakların başlangıç günleri dikkate alındı. Daha sonra bunları kullanarak, zaman serisi analizi için, aylık ortalama atak sayıları hesaplandı.
Bulgular: Oral aftlar için Mayıs ve Ekim aylarında, genital ülserler için Ağustos ayında ortalama atak sayıları daha yüksek olmasına rağmen, zaman serisi analizi ile mevsimsellik doğrulanamadı.
Sonuç: Pubmed’de yapılan literatür taramasının ardından, Behçet Hastalığının mukokutanöz lezyonları için mevsimsellik tespit etmeyen sadece bir çalışma ve oral aft için mevsimsellik tespit eden sadece bir çalışma bulundu. Ancak bu çalışmalarda zaman serisi analizinin kullanılmadığını belirtmekte fayda vardır. Bu çalışma retrospektif olduğu için sonuçları zaman serisi analizini kullanılarak, günlük-tabanlı prospektif çalışmalarla doğrulanmalıdır.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | Fettahlioglu Karaman B (2022). Are mucocutaneous lesions seasonal in Behçet's disease?. , 16 - 20. 10.17826/cumj.980169 |
| Chicago | Fettahlioglu Karaman Bilge Are mucocutaneous lesions seasonal in Behçet's disease?. (2022): 16 - 20. 10.17826/cumj.980169 |
| MLA | Fettahlioglu Karaman Bilge Are mucocutaneous lesions seasonal in Behçet's disease?. , 2022, ss.16 - 20. 10.17826/cumj.980169 |
| AMA | Fettahlioglu Karaman B Are mucocutaneous lesions seasonal in Behçet's disease?. . 2022; 16 - 20. 10.17826/cumj.980169 |
| Vancouver | Fettahlioglu Karaman B Are mucocutaneous lesions seasonal in Behçet's disease?. . 2022; 16 - 20. 10.17826/cumj.980169 |
| IEEE | Fettahlioglu Karaman B "Are mucocutaneous lesions seasonal in Behçet's disease?." , ss.16 - 20, 2022. 10.17826/cumj.980169 |
| ISNAD | Fettahlioglu Karaman, Bilge. "Are mucocutaneous lesions seasonal in Behçet's disease?". (2022), 16-20. https://doi.org/10.17826/cumj.980169 |
| APA | Fettahlioglu Karaman B (2022). Are mucocutaneous lesions seasonal in Behçet's disease?. Cukurova Medical Journal, 47(1), 16 - 20. 10.17826/cumj.980169 |
| Chicago | Fettahlioglu Karaman Bilge Are mucocutaneous lesions seasonal in Behçet's disease?. Cukurova Medical Journal 47, no.1 (2022): 16 - 20. 10.17826/cumj.980169 |
| MLA | Fettahlioglu Karaman Bilge Are mucocutaneous lesions seasonal in Behçet's disease?. Cukurova Medical Journal, vol.47, no.1, 2022, ss.16 - 20. 10.17826/cumj.980169 |
| AMA | Fettahlioglu Karaman B Are mucocutaneous lesions seasonal in Behçet's disease?. Cukurova Medical Journal. 2022; 47(1): 16 - 20. 10.17826/cumj.980169 |
| Vancouver | Fettahlioglu Karaman B Are mucocutaneous lesions seasonal in Behçet's disease?. Cukurova Medical Journal. 2022; 47(1): 16 - 20. 10.17826/cumj.980169 |
| IEEE | Fettahlioglu Karaman B "Are mucocutaneous lesions seasonal in Behçet's disease?." Cukurova Medical Journal, 47, ss.16 - 20, 2022. 10.17826/cumj.980169 |
| ISNAD | Fettahlioglu Karaman, Bilge. "Are mucocutaneous lesions seasonal in Behçet's disease?". Cukurova Medical Journal 47/1 (2022), 16-20. https://doi.org/10.17826/cumj.980169 |
