TY - JOUR TI - Host variations in SARS-CoV-2 infection AB - t: The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the zoonotic pathogen that causes the “Coronavirus Disease of 2019 (COVID-19)”, and COVID-19 itself is yet to be thoroughly understood. Both the disease as well as the mechanisms by which the host interacts with the SARS-CoV-2 have not been fully enlightened. The epidemiological factors –e.g. age, sex, race-, the polymorphisms of the host proteins, the blood types and individual differences have all been in discussions about affecting the progression and the course of COVID-19 both individually and collectively, as their effects are mostly interwoven. We focused mainly on the effect of polymorphic variants of the host proteins that have been shown to take part in and/or affect the pathogenesis of COVID-19. Additionally, how the procedures of diagnosing and treating COVID-19 are affected by these variants and what possible changes can be implemented are the other questions, which are sought to be answered. AU - Savcı, Elif Zeynep AU - Gunes Altuntas, Evrim AU - uncuoğlu, dilruba beyza AU - Altıok, Doruk AU - Alkan, Kamil AU - Tekeli, Cansu AU - Ünal, Sinan AU - Dönmüş, Beyza AU - suiçmez, evren AU - Namdar, Dilara Sultan AU - mendi, aysegul AU - Özkara, Büşra AU - Demir Dora, Devrim AU - Cengiz Seval, Guldane AU - Karagülleoğlu, Zeynep Yağmur AU - Tunçer, Gizem AU - Kılınç, Buğrahan Regaip AU - Bengi, Vahdi Umut AU - Kilic, Pelin AU - Çetin, Güneysu DO - 10.3906/biy-2104-67 PY - 2021 JO - Turkish Journal of Biology VL - 45 IS - 4 SN - 1300-0152 SP - 404 EP - 424 DB - TRDizin UR - http://search/yayin/detay/520445 ER -