TY  - JOUR
TI  - Is Having Inflammatory Bowel Disease a Risk Factor for
Severe Acute Respiratory Syndrome Coronavirus 2?
AB  - Background: The severe acute respiratory syndrome coronavirus 2 virus was found to have effects not only in the lungs but also in
many different organs. We aimed to evaluate the management of our patients with inflammatory bowel disease in this pandemic, the
incidence of coronavirus disease 2019 in terms of clinical, medical treatment, and features of inflammatory bowel disease, and to investigate the effects of the severe acute respiratory syndrome coronavirus 2 on this particular group of patients.
Methods: During the coronavirus disease 2019 pandemic, 207 patients who had inflammatory bowel disease for at least 6 months were
questioned for coronavirus disease 2019 at their outpatient clinic admissions, and their medical records were evaluated prospectively.
Results: Of the 207 patients, 146 had Crohn’s disease. The mean disease duration was determined as 118.15 ± 72.85 months. Of the
patients, 127 (61.4%) were using mesalazine, 110 (53.1%) azathioprine, and 148 (71.5%) biological agents. It was found that 66 (31.9%)
patients changed their medications during the coronavirus disease 2019 pandemic. As a medication change, anti-Tumor Necrosis
Factor (TNF) dose was observed to be omitted most frequently at a rate of 80%. Diarrhea was present in 20.8%, abdominal pain in
20.3%, nausea in 10.6%, anorexia in 13.5%, and weight loss in 15.9% of the patients. Twelve (5.79%) patients were diagnosed with
coronavirus disease 2019. Lung involvement was present in 11 (91.7%) of the patients diagnosed with coronavirus disease 2019. Of the
patients diagnosed and not diagnosed with coronavirus disease 2019, 75% vs. 71.6% were using biological agents (P = .80), respectively.
Half of the patients diagnosed with coronavirus disease 2019 were active in terms of inflammatory bowel disease at the time of diagnosis, and 2 of these patients were severely active.
Conclusion: The incidence of coronavirus disease 2019 infection in patients with inflammatory bowel disease was not different from the
general population during the severe acute respiratory syndrome coronavirus 2 pandemic. Coronavirus disease 2019 infection does not
progress with poor prognosis in patients with inflammatory bowel disease who receive immunosuppressive therapy including biological
agents.
AU  - Akyuz, Filiz
AU  - Kaymakoglu, Sabahattin
AU  - Beşışık, Fatih
AU  - Ozgur, Ilker
AU  - Keskin, Metin
AU  - Kose, Murat
AU  - Medetalibeyoglu, Alpay
AU  - EREL GEZEGEN, CANSU
AU  - Çavuş, Bilger
AU  - YAKUT, AYSUN
AU  - Demir, Kadir
AU  - Ormeci, Asli
AU  - Imanov, Ziya
AU  - Senkal, Ibrahim volkan
DO  - 10.5152/tjg.2022.211113
PY  - 2022
JO  - Turkish Journal of Gastroenterology
VL  - 33
IS  - 3
SN  - 1300-4948
SP  - 196
EP  - 204
DB  - TRDizin
UR  - http://search/yayin/detay/520611
ER  -