TY  - JOUR
TI  - Bisphenol A Exposure in Exclusively Breastfed Infants and Lactating
Women: An Observational Cross-sectional Study
AB  - Objective: Bisphenol A (BPA) is a known endocrine disruptor and free BPA will interact with estrogen. BPA is also fat soluble and will
therefore contaminate breast milk. The European Food Safety Authority has set a limit for temporary tolerable daily intake of 4 µg/kg
body weight/day in breastfeeding infants. The aim of this study was to measure human milk BPA concentrations in Turkish women and
thus exclusively breastfed infants’ exposure to BPA.
Methods: Healthy, postnatal, exclusively breastfeeding women were recruited and breast milk samples were collected. Free BPA
concentration was analyzed in the milk samples using competitive enzyme-linked immunosorbent assay. Participants’ demographic
characteristics and nutritional habits were investigated through face-to-face interviews using a detailed questionnaire.
Results: Eighty women participated. Median milk free BPA level was 0.63 µg/L. There was no statistically significant association between
maternal body mass index, birth type, parity, infant birth week, infant birth weight, and human milk BPA concentration. Nevertheless,
there was a significant association between human milk BPA level and consumption of fast-food and carbonated drinks (p=0.022 and
p=0.018, respectively). Exclusively breastfed infants’ mean BPA exposure was 0.0099±0.0079 µg/kg bw/day. There was a moderate
negative significant correlation between infant BPA exposure and infant current body weight (r=0.327, p=0.003).
Conclusion: BPA exposure in exclusively breastfed infants was within accepted limits and the current dietary exposure level of infants
in this cohort was safe.
AU  - samur, gulhan
AU  - Çiftçi, Seda
AU  - YALÇIN, Siddika Songül
DO  - 10.4274/jcrpe.galenos.2020.2021.0305
PY  - 2021
JO  - Journal of Clinical Research in Pediatric Endocrinology
VL  - 13
IS  - 4
SN  - 1308-5727
SP  - 375
EP  - 383
DB  - TRDizin
UR  - http://search/yayin/detay/521125
ER  -