TY  - JOUR
TI  - Noncoding RNAs in apoptosis: identification and function
AB  - Apoptosis is a vital cellular process that is critical for the maintenance of homeostasis in health and disease. The derailment
of apoptotic mechanisms has severe consequences such as abnormal development, cancer, and neurodegenerative diseases. Thus, there
exist complex regulatory mechanisms in eukaryotes to preserve the balance between cell growth and cell death. Initially, proteincoding genes were prioritized in the search for such regulatory macromolecules involved in the regulation of apoptosis. However,
recent genome annotations and transcriptomics studies have uncovered a plethora of regulatory noncoding RNAs that have the ability
to modulate not only apoptosis but also many other biochemical processes in eukaryotes. In this review article, we will cover a brief
summary of apoptosis and detection methods followed by an extensive discussion on microRNAs, circular RNAs, and long noncoding RNAs in apoptosis.
AU  - ERDOGAN VATANSEVER, IPEK
AU  - Kara, Merve
AU  - Tüncel, Özge
AU  - Akgül, Bünyamin
AU  - Yaylak, Bilge
DO  - 10.3906/biy-2109-35
PY  - 2022
JO  - Turkish Journal of Biology
VL  - 46
IS  - 1
SN  - 1300-0152
SP  - 1
EP  - 40
DB  - TRDizin
UR  - http://search/yayin/detay/521614
ER  -