Yıl: 2022 Cilt: 44 Sayı: 1 Sayfa Aralığı: 63 - 67 Metin Dili: İngilizce DOI: 10.14744/etd.2021.32855 İndeks Tarihi: 20-06-2022

Analysis of HIV Infection in Cyprus Using a Mathematical Model

Öz:
Objective: The Mediterranean island of Cyprus has a high rate of human transit as a result of tourism, human trafficking, and migration, which could contribute to the rate of HIV infection. The island is divided into 2 states – the northern portion is mainly populated by Turkish-Cypriots, and the southern portion is populated by Greek-Cypriots. The aim of this study was to assess the dynamics of HIV infection in both segments of Cyprus using a mathematical model. Materials and Methods: Data of HIV-positive individuals diagnosed during the period 1997–2018 in northern Cyprus were obtained from the Turkish Republic of Northern Cyprus Ministry of Health database, yielding a total of 129 cases, and data for the southern region, the Republic of Cyprus, were retrieved from a European Centre for Disease Prevention and Control (ECDC) 2013 report and ECDC/World Health Organization 2017 data. The total number of reported HIV infections was 1057. A mathematical model was used to evaluate the current and future HIV infection rate. Results: Stability analysis of the equilibrium point – disease-free or endemic – was conducted using the Lyapunov function. The basic reproduction number, represented as R0, is a measure of the potential for disease spread and serves as a threshold for stability. The R0 value was 0.83 in northern Cyprus and 0.040 in southern Cyprus. An R0 indicated a disease-free equilibrium. Conclusion: The calculations suggest that there is no current HIV epidemic on either part of the island; however, the model predicted a significant increase in the near future.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • 1. WHO. HIV/AIDS Key facts [Internet]. 2018. Available from: URL: https:// www.who.int/news-room/fact-sheets/detail/hiv-aids. Accessed Feb 26, 2019.
  • 2. U.S Department of State. Trafficking in Persons Report - June 2018. Available from: URL: https://www.state.gov/reports/2018-trafficking-in-persons-report/
  • 3. Gözügüzel E. TRNC Tourism Planning Department, “Tourism Planning Department-Tourism Statistics 2018 [Internet]. T.C. Polis Akademisi Güvenlik Bilimleri Enstitüsü; 2014. Available from: URL: https:// tez.yok.gov.tr/UlusalTezMerkezi/tezDetay.jsp?id=UKl9NcCQf9MNEzlIu66LUw&no=84t-gjfeJqw3abAhTBRpfg
  • 4. Altinay L, Altinay M, Bicak HA. Political scenarios: the future of the North Cyprus tou-rism industry. Int J Contemp Hosp Manag 2002; 14(4): 176–82.
  • 5. ECDC. Technical mission: HIV in Cyprus, 15–17 October 2014. Available from: URL: https://www.ecdc.europa.eu/en/publications-data/ technical-mission-hiv-cyprus-15-17-october. Accessed Apr 12, 2018.
  • 6. ECDC and WHO. HIV/AIDS surveillance in Europe 2017 [Internet]. Available from: URL: https://ecdc.europa.eu/en/publications-data/ hivaids-surveillance-europe-2017-2016-data. Accessed Apr 12, 2017.
  • 7. TRNC Tourism Planning Department. Tourism Planning Department-Tourism Statistics 2018 [Internet]. Available from: URL: http:// turizmplanlama.gov.ct.tr/TUR%C4%B0ZM-%C4%B0STAT%C4%B0ST%C4%B0KLER%C4%B0.
  • 8. Republic of Cyprus Demographic Report Statistical Service. Republic of Cyprus de-mographic report 2015 [Internet]. Available from: URL: http://www.mof.gov.cy/mof/cystat/statistics.nsf/All/8CC894A 299589FB4C22581E50036BF7C/$file/DEMOGRAPHIC_REPORT-2015-301116.pdf?OpenElement. Accessed Feb 27, 2019.
  • 9. Gold News. Kadis: Number of foreign students in Cyprus has tripled [Internet]. 2017. Available from: URL: http://www.goldnews.com.cy/ en/companies/number-of-foreign-students-in-cyprus-has-tripled-inthepast-couple-of-years. Accessed 27, 2019
  • 10. Kıbrıs Postası. Özyiğit announced the statistics of students study- ing at universities in TRNC [Internet]. Available from: URL: http:// www.kibrispostasi.com/mobile/ozyigit-kktcdeki-universitelerde-egitim-goren-ogrencilerin-i?fbclid=IwAR3ewIfSXbV-nz-Xz8cV4eo9Mzd6kRTIVhL7h3T81aNKixrgGhTPIOJ_Te0. Accessed Feb 27, 2019.
  • 11. TRNC State Planning Organization. Turkish Republic of Northern Cyprus Statistical year book 2020 prime ministry state planning organization statistics and research department [Internet]. Available from: URL: http://www.devplan.org/Eco-sos/Book/SEG-2018.pdf. Accessed Dec, 14, 2021.
  • 12. Saad FT, Sanlidag T, Hincal E, Sayan M, Baba IA, Kaymakamzade B. Global stability analysis of HIV+ model. Springer Link, 2018.p. 830– 9. Available from: URL: http://link.springer.com/10.1007/978-3- 030-04164-9_109.
  • 13. Murray SM, Howard M. Center Finding in E. Coli and the role of mathematical modeling: past, present and future. J Mol Biol 2019; 431(5): 928–38.
  • 14. Khatun Z, Islam MS, Ghosh U. Mathematical modeling of hepatitis B virus infection incorporating immune responses. Sensors Int 2020; 1: 100017.
  • 15. Kanyiri CW, Mark K, Luboobi L. Mathematical analysis of influenza a dynamics in the emergence of drug resistance. Comput Math Methods Med 2018; 2018: 2434560.
APA Sultanoglu N, SAAD F, Sanlidag T, Hıncal E, SAYAN M, Kaymakamzade B, süer k (2022). Analysis of HIV Infection in Cyprus Using a Mathematical Model. , 63 - 67. 10.14744/etd.2021.32855
Chicago Sultanoglu Nazife,SAAD FAROUK,Sanlidag Tamer,Hıncal Evren,SAYAN MURAT,Kaymakamzade Bilgen,süer kaya Analysis of HIV Infection in Cyprus Using a Mathematical Model. (2022): 63 - 67. 10.14744/etd.2021.32855
MLA Sultanoglu Nazife,SAAD FAROUK,Sanlidag Tamer,Hıncal Evren,SAYAN MURAT,Kaymakamzade Bilgen,süer kaya Analysis of HIV Infection in Cyprus Using a Mathematical Model. , 2022, ss.63 - 67. 10.14744/etd.2021.32855
AMA Sultanoglu N,SAAD F,Sanlidag T,Hıncal E,SAYAN M,Kaymakamzade B,süer k Analysis of HIV Infection in Cyprus Using a Mathematical Model. . 2022; 63 - 67. 10.14744/etd.2021.32855
Vancouver Sultanoglu N,SAAD F,Sanlidag T,Hıncal E,SAYAN M,Kaymakamzade B,süer k Analysis of HIV Infection in Cyprus Using a Mathematical Model. . 2022; 63 - 67. 10.14744/etd.2021.32855
IEEE Sultanoglu N,SAAD F,Sanlidag T,Hıncal E,SAYAN M,Kaymakamzade B,süer k "Analysis of HIV Infection in Cyprus Using a Mathematical Model." , ss.63 - 67, 2022. 10.14744/etd.2021.32855
ISNAD Sultanoglu, Nazife vd. "Analysis of HIV Infection in Cyprus Using a Mathematical Model". (2022), 63-67. https://doi.org/10.14744/etd.2021.32855
APA Sultanoglu N, SAAD F, Sanlidag T, Hıncal E, SAYAN M, Kaymakamzade B, süer k (2022). Analysis of HIV Infection in Cyprus Using a Mathematical Model. Erciyes Medical Journal, 44(1), 63 - 67. 10.14744/etd.2021.32855
Chicago Sultanoglu Nazife,SAAD FAROUK,Sanlidag Tamer,Hıncal Evren,SAYAN MURAT,Kaymakamzade Bilgen,süer kaya Analysis of HIV Infection in Cyprus Using a Mathematical Model. Erciyes Medical Journal 44, no.1 (2022): 63 - 67. 10.14744/etd.2021.32855
MLA Sultanoglu Nazife,SAAD FAROUK,Sanlidag Tamer,Hıncal Evren,SAYAN MURAT,Kaymakamzade Bilgen,süer kaya Analysis of HIV Infection in Cyprus Using a Mathematical Model. Erciyes Medical Journal, vol.44, no.1, 2022, ss.63 - 67. 10.14744/etd.2021.32855
AMA Sultanoglu N,SAAD F,Sanlidag T,Hıncal E,SAYAN M,Kaymakamzade B,süer k Analysis of HIV Infection in Cyprus Using a Mathematical Model. Erciyes Medical Journal. 2022; 44(1): 63 - 67. 10.14744/etd.2021.32855
Vancouver Sultanoglu N,SAAD F,Sanlidag T,Hıncal E,SAYAN M,Kaymakamzade B,süer k Analysis of HIV Infection in Cyprus Using a Mathematical Model. Erciyes Medical Journal. 2022; 44(1): 63 - 67. 10.14744/etd.2021.32855
IEEE Sultanoglu N,SAAD F,Sanlidag T,Hıncal E,SAYAN M,Kaymakamzade B,süer k "Analysis of HIV Infection in Cyprus Using a Mathematical Model." Erciyes Medical Journal, 44, ss.63 - 67, 2022. 10.14744/etd.2021.32855
ISNAD Sultanoglu, Nazife vd. "Analysis of HIV Infection in Cyprus Using a Mathematical Model". Erciyes Medical Journal 44/1 (2022), 63-67. https://doi.org/10.14744/etd.2021.32855