Güncel Literatür Işığında Akut Respiratuar Distres Sendromu

kalaycıoğlu, Gülşen; Pinar, Rukiye; ÜÇERİZ, Ayşenur

Güncel Literatür Işığında Akut Respiratuar Distres Sendromu

Rukiye Pınar BÖLÜKTAŞ, (İstanbul Sabahattin Zaim Üniversitesi, Sağlık Bilimleri Fakültesi, Hemşirelik Bölümü, İstanbul, Türkiye)

Gülşen KALAYCIOĞLU, (Sağlık Bilimleri Üniversitesi, İstanbul Bakırköy Doktor Sadi Konuk Eğitim Araştırma Hastanesi, İç Hastalıkları Kliniği, İstanbul, Türkiye)

Ayşenur ÜÇERİZ (İstanbul Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, İstanbul, Türkiye)

Kocaeli Tıp Dergisi

13 1

Yıl: 2021 Cilt: 10 Sayı: Ek 2 Sayfa Aralığı: 148 - 159 Metin Dili: Türkçe İndeks Tarihi: 22-06-2022

Güncel Literatür Işığında Akut Respiratuar Distres Sendromu

Öz:

Morbidite ve mortalitesi oldukça yüksek olan, hayatta kalan hastaların ise yaşam kalitesini olumsuz yönde etkileyen Akut Respiratuar Distres Sendromu 50 yılı aşkın süredir yıkıcı bir sağlık sorunu olarak tıp dünyasını meşgul etmeye devam etmektedir. Sepsis, yağ embolisi, aspirasyon, toksik gaz ve dumanların inhalasyonu, travma ve akut pankreatit gibi birçok faktör akciğerlerde patolojik süreci tetikleyerek hipoksemi, hiperkapni ve akciğer kompliyansında azalmaya yol açar. Tedavide etkinliği kanıtlanmış herhangi bir ilaç bulunmamaktadır. Tedavi, altta yatan neden iyileşene kadar, akciğer koruyucu mekanik ventilasyon (tidal volüm, pozitif end-ekspiratuar basınç, prone pozisyonu, recruitment manevra) uygulamasını içerir. Optimal sıvı rejimi ARDS’nin dönemine göre farklılık gösterir. Hastaların beslenmesine ilişkin yapılan araştırma sonuçları birbiri ile tutarsızdır. Düşük tidal volüm (4-8 mL/kg, tahmini vücut ağırlığına göre) + sınırlı plato basıncı (<30 cmH2O) mortaliteyi azaltan ispatlanmış tek tedavidir. Bu derlemede hala bilinmeyenleri çok olan, Akut Respiratuar Distres Sendromunun güncel literatür ışığında etyoloji, epidemiyoloji, patofizyoloji, tanı ve tedavisi ele alınacaktır.

Anahtar Kelime:

Acute Respiratory Distress Syndrome in the Light of Current Literature

Öz:

Acute Respiratory Distress Syndrome, which has high morbidity and mortality and negatively affects the quality of life of surviving patients, continues to occupy the medical world as a devastating health problem for more than 50 years. Many factors such as sepsis, fat embolism, aspiration, inhalation of toxic gases and fumes, trauma and acute pancreatitis trigger the pathological process in the lungs, leading to hypoxemia, hypercapnia and a decrease in lung compliance. There is no medication with proven efficacy in treatment. Treatment includes lung protective mechanical ventilation (tidal volume, positive end-expiratory pressure, prone position, recruitment maneuver) until the underlying cause is resolved. The optimal fluid regime differs according to the period of Acute Respiratory Distress Syndrome. Research results on the nutrition of patients are inconsistent. Low tidal volume (4-8 mL / kg according to estimated body weight) + limited plateau pressure (<30 cmH2O) is the only proven treatment that reduces mortality. In this review, the etiology, epidemiology, pathophysiology, diagnosis and treatment of Acute Respiratory Distress Syndrome, which is still unknown, will be discussed in the light of current literature.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Derleme Erişim Türü: Erişime Açık

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APA	Pinar R, kalaycıoğlu G, ÜÇERİZ A (2021). Güncel Literatür Işığında Akut Respiratuar Distres Sendromu. , 148 - 159.
Chicago	Pinar Rukiye,kalaycıoğlu Gülşen,ÜÇERİZ Ayşenur Güncel Literatür Işığında Akut Respiratuar Distres Sendromu. (2021): 148 - 159.
MLA	Pinar Rukiye,kalaycıoğlu Gülşen,ÜÇERİZ Ayşenur Güncel Literatür Işığında Akut Respiratuar Distres Sendromu. , 2021, ss.148 - 159.
AMA	Pinar R,kalaycıoğlu G,ÜÇERİZ A Güncel Literatür Işığında Akut Respiratuar Distres Sendromu. . 2021; 148 - 159.
Vancouver	Pinar R,kalaycıoğlu G,ÜÇERİZ A Güncel Literatür Işığında Akut Respiratuar Distres Sendromu. . 2021; 148 - 159.
IEEE	Pinar R,kalaycıoğlu G,ÜÇERİZ A "Güncel Literatür Işığında Akut Respiratuar Distres Sendromu." , ss.148 - 159, 2021.
ISNAD	Pinar, Rukiye vd. "Güncel Literatür Işığında Akut Respiratuar Distres Sendromu". (2021), 148-159.

APA	Pinar R, kalaycıoğlu G, ÜÇERİZ A (2021). Güncel Literatür Işığında Akut Respiratuar Distres Sendromu. Kocaeli Tıp Dergisi, 10(Ek 2), 148 - 159.
Chicago	Pinar Rukiye,kalaycıoğlu Gülşen,ÜÇERİZ Ayşenur Güncel Literatür Işığında Akut Respiratuar Distres Sendromu. Kocaeli Tıp Dergisi 10, no.Ek 2 (2021): 148 - 159.
MLA	Pinar Rukiye,kalaycıoğlu Gülşen,ÜÇERİZ Ayşenur Güncel Literatür Işığında Akut Respiratuar Distres Sendromu. Kocaeli Tıp Dergisi, vol.10, no.Ek 2, 2021, ss.148 - 159.
AMA	Pinar R,kalaycıoğlu G,ÜÇERİZ A Güncel Literatür Işığında Akut Respiratuar Distres Sendromu. Kocaeli Tıp Dergisi. 2021; 10(Ek 2): 148 - 159.
Vancouver	Pinar R,kalaycıoğlu G,ÜÇERİZ A Güncel Literatür Işığında Akut Respiratuar Distres Sendromu. Kocaeli Tıp Dergisi. 2021; 10(Ek 2): 148 - 159.
IEEE	Pinar R,kalaycıoğlu G,ÜÇERİZ A "Güncel Literatür Işığında Akut Respiratuar Distres Sendromu." Kocaeli Tıp Dergisi, 10, ss.148 - 159, 2021.
ISNAD	Pinar, Rukiye vd. "Güncel Literatür Işığında Akut Respiratuar Distres Sendromu". Kocaeli Tıp Dergisi 10/Ek 2 (2021), 148-159.