Yıl: 2022 Cilt: 37 Sayı: 1 Sayfa Aralığı: 79 - 84 Metin Dili: İngilizce DOI: 10.4274/MMJ.galenos.2022.75282

Adenoma Detection Rate in Colonoscopic Screening with Ketamine-based Sedation: A Prospective Observational Study

Öz:
Objective: This study aimed to determine the relationship between one of the most commonly used anesthesia techniques, ketamine- based sedation, on the value of adenoma detection rate (ADR) during colonoscopy screening. Methods: This prospective, observational study included 140 patients, who underwent a standard colonoscopy preparation before the procedure. Sedation regimens included ketamine at 0.5 mg/kg and propofol at 0.5 mg/kg. Additional doses of propofol were administered at 0.5 mg/kg to maintain the Ramsey Sedation scale. Baseline characteristics, ADR, bowel preparation quality according to the Chicago bowel preparation (CHBP) scale, cecal intubation, colonoscopy removal, and complications were analyzed. Results: The mean age of patients was 55.76 years; 40 (28.6%) were males and 100 (71.4%) were females. The ADR was 43.57%, wherein 15.71% in males and 27.86% in females. There were 43.6% adenomas, 17.9% biopsies, and 22.9% polypectomies. The largest location of adenomas/polyps were in the rectum and sigmoid and ascending colon (p=0.11), a biopsy of the sigmoid colon and ileum (p<0.05), polypectomy of the rectum and sigmoid and ascending colon (p<0.05). The cecal intubation was 93.6% with a withdrawal time that is >6 min in most patients (80%) (p<0.05). The CHBP scale showed good bowel preparation (p<0.05) without complications. Conclusions: Ketamine-based sedation is in good overall correlation with ADR. Therefore, the sedation technique should be included for ADR assessment in the future.
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Fen > Tıp > Genel ve Dahili Tıp
Fen > Tıp > Genel ve Dahili Tıp

Ketamin Bazlı Sedasyon ile Kolonoskopik Taramada Adenom Tespit Oranı: Prospektif Gözlemsel Bir Çalışma

Öz:
Amaç: Bu çalışmada en sık kullanılan anestezi tekniklerinden biri olan ketamin bazlı sedasyon ile kolonoskopi taraması sırasında adenom tespit oranının (ADR) değeri arasındaki ilişkinin belirlenmesi amaçlanmıştır. Yöntemler: Bu prospektif, gözlemsel çalışmaya, işlemden önce standart kolonoskopi hazırlığı yapılan 140 hasta dahil edildi. Sedasyon rejimleri, 0,5 mg/kg ketamin ve 0,5 mg/kg propofol içeriyordu. Ramsey Sedasyon skalasını korumak için 0,5 mg/kg’de ek propofol dozları uygulandı. Temel özellikler, ADR, Chicago barsak hazırlık (CHBP) ölçeğine göre bağırsak hazırlığı kalitesi, çekal entübasyon, kolonoskopinin çıkarılması ve komplikasyonlar analiz edildi. Bulgular: Hastaların ortalama yaşı 55,76 yıldı; 40’ı (%28,6) erkek, 100’ü (%71,4) kadındı. ADR, erkeklerde %15,71 ve kadınlarda %27,86 olmak üzere %43,57 idi. %43,6 adenom, %17,9 biyopsi ve %22,9 polipektomi vardı. Adenomların/poliplerin en büyük yeri rektumda ve sigmoid ve çıkan kolonda (p=0,11), sigmoid kolon ve ileum biyopsisinde (p<0,05), rektum ve sigmoidde ve çıkan kolonda polipektomi (p<0,05) idi. Çekal entübasyon, çoğu hastada (%80) >6 dakika olan bir geri çekme süresi ile %93.6 idi (p<0,05). CHBP ölçeği komplikasyonsuz iyi bir barsak hazırlığı (p<0,05) gösterdi. Sonuçlar: Ketamin bazlı sedasyon, ADR ile genel olarak iyi bir korelasyon içindedir. Bu nedenle, gelecekteki çalışmalarda ADR değerlendirmesi için sedasyon tekniği dahil edilmelidir.
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Konular:
Fen > Tıp > Genel ve Dahili Tıp
Fen > Tıp > Genel ve Dahili Tıp
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA KOVACEVIC M, RIZVANOVIC N, ADILOVIC A, BARUCIJA N, ABAZOVIC A (2022). Adenoma Detection Rate in Colonoscopic Screening with Ketamine-based Sedation: A Prospective Observational Study. Medeniyet Medical Journal, 37(1), 79 - 84. 10.4274/MMJ.galenos.2022.75282
Chicago KOVACEVIC Mirza,RIZVANOVIC Nermina,ADILOVIC Adisa SABANOVIC,BARUCIJA Nedim,ABAZOVIC Anida Adenoma Detection Rate in Colonoscopic Screening with Ketamine-based Sedation: A Prospective Observational Study. Medeniyet Medical Journal 37, no.1 (2022): 79 - 84. 10.4274/MMJ.galenos.2022.75282
MLA KOVACEVIC Mirza,RIZVANOVIC Nermina,ADILOVIC Adisa SABANOVIC,BARUCIJA Nedim,ABAZOVIC Anida Adenoma Detection Rate in Colonoscopic Screening with Ketamine-based Sedation: A Prospective Observational Study. Medeniyet Medical Journal, vol.37, no.1, 2022, ss.79 - 84. 10.4274/MMJ.galenos.2022.75282
AMA KOVACEVIC M,RIZVANOVIC N,ADILOVIC A,BARUCIJA N,ABAZOVIC A Adenoma Detection Rate in Colonoscopic Screening with Ketamine-based Sedation: A Prospective Observational Study. Medeniyet Medical Journal. 2022; 37(1): 79 - 84. 10.4274/MMJ.galenos.2022.75282
Vancouver KOVACEVIC M,RIZVANOVIC N,ADILOVIC A,BARUCIJA N,ABAZOVIC A Adenoma Detection Rate in Colonoscopic Screening with Ketamine-based Sedation: A Prospective Observational Study. Medeniyet Medical Journal. 2022; 37(1): 79 - 84. 10.4274/MMJ.galenos.2022.75282
IEEE KOVACEVIC M,RIZVANOVIC N,ADILOVIC A,BARUCIJA N,ABAZOVIC A "Adenoma Detection Rate in Colonoscopic Screening with Ketamine-based Sedation: A Prospective Observational Study." Medeniyet Medical Journal, 37, ss.79 - 84, 2022. 10.4274/MMJ.galenos.2022.75282