TY  - JOUR
TI  - Adenoma Detection Rate in Colonoscopic Screening with
Ketamine-based Sedation: A Prospective Observational
Study
AB  - Objective: This study aimed to determine the relationship between
one of the most commonly used anesthesia techniques, ketamine-
based sedation, on the value of adenoma detection rate (ADR) during
colonoscopy screening.
Methods: This prospective, observational study included 140 patients, who
underwent a standard colonoscopy preparation before the procedure.
Sedation regimens included ketamine at 0.5 mg/kg and propofol at 0.5
mg/kg. Additional doses of propofol were administered at 0.5 mg/kg to
maintain the Ramsey Sedation scale. Baseline characteristics, ADR, bowel
preparation quality according to the Chicago bowel preparation (CHBP)
scale, cecal intubation, colonoscopy removal, and complications were
analyzed.
Results: The mean age of patients was 55.76 years; 40 (28.6%) were males
and 100 (71.4%) were females. The ADR was 43.57%, wherein 15.71% in
males and 27.86% in females. There were 43.6% adenomas, 17.9% biopsies,
and 22.9% polypectomies. The largest location of adenomas/polyps were
in the rectum and sigmoid and ascending colon (p=0.11), a biopsy of
the sigmoid colon and ileum (p<0.05), polypectomy of the rectum and
sigmoid and ascending colon (p<0.05). The cecal intubation was 93.6%
with a withdrawal time that is >6 min in most patients (80%) (p<0.05).
The CHBP scale showed good bowel preparation (p<0.05) without
complications.
Conclusions: Ketamine-based sedation is in good overall correlation
with ADR. Therefore, the sedation technique should be included for ADR
assessment in the future.
AU  - KOVACEVIC, Mirza
AU  - RIZVANOVIC, Nermina
AU  - BARUCIJA, Nedim
AU  - ABAZOVIC, Anida
AU  - ADILOVIC, Adisa SABANOVIC
DO  - 10.4274/MMJ.galenos.2022.75282
PY  - 2022
JO  - Medeniyet Medical Journal
VL  - 37
IS  - 1
SN  - 2149-2042
SP  - 79
EP  - 84
DB  - TRDizin
UR  - http://search/yayin/detay/523667
ER  -