TY  - JOUR
TI  - Comparison of the Algan Hemostatic Agent with Floseal in Rat Liver 
Laceration Bleeding Model
AB  - Objective: Major vascular injury is one of the most important causes of death after trauma. The effective 
and speedy control of the hemorrhage is crucial in reducing deaths. Many products are used for this purpose. 
Today, however, an ideal product has not yet been produced and there is a strong demand for such effective 
hemostatic products. The aim of this study is to compare the efficacy of Algan hemostatic agent with Floseal 
in the liver laceration model in rats.
Materials and Methods: A total of 28 rats were used in the study. Rats were divided into 4 groups, each 
consisting of 7 rats. Experimental liver laceration was established. In the control group, saline-impregnated 
gauze was applied. Algan hemostatic agent-impregnated sponge, Algan hemostatic agent powder, and Floseal 
gel were applied to the experimental groups.
Results: There was no difference in bleeding control among the Algan hemostatic agent powder, Algan 
hemostatic agent-impregnated sponge, and Floseal. When compared to the control group, Algan hemostatic 
agent powder, Algan hemostatic agent-impregnated sponge, and Floseal were found to be very effective in 
bleeding control, respectively (P=.001, .012, and .002), in the experimental groups.
Conclusion: This study showed that the properties of both Algan hemostatic agent powder and Algan 
hemostatic agent-impregnated sponge for controlling bleeding are similar to Floseal. Considering other characteristics such as Algan hemostatic agent’s naturalness, easy applicability, and low cost, Algan hemostatic 
agent has been a promising effective hemostatic agent.
AU  - Ozbaykus, Abdullah Canberk
AU  - BİNNETOĞLU, Kenan
AU  - KUMANDAS, ALI
AU  - Ekici, Hüsamettin
DO  - 10.5152/eurasianjmed.2022.21004
PY  - 2022
JO  - Eurasian Journal of Medicine
VL  - 54
IS  - 1
SN  - 1308-8734
SP  - 36
EP  - 40
DB  - TRDizin
UR  - http://search/yayin/detay/524255
ER  -