TY  - JOUR
TI  - Evaluation of Magnetic Resonance Elastography and 
Transient Elastography for Liver Fibrosis and Steatosis 
Assessments in the Liver Transplant Setting
AB  - Background: Liver graft fibrosis affects long-term graft and patient survival in liver transplant recipients. Transient elastography and 
magnetic resonance elastography are widely used for the assessment of liver fibrosis in routine clinical practice, but are limited in liver 
transplant settings. The aims of the present study were to evaluate the accuracy of magnetic resonance elastography and transient 
elastograph in the assessment of liver fibrosis in liver transplant recipients, and to determine the recurrence rates of post-transplant 
hepatic steatosis and liver fibrosis.
Methods: A total of 126 consecutive liver transplant recipients were included. Magnetic resonance elastography and transient elastography were performed for to measure liver stiffness.
Results: The most common cause of liver transplantation was hepatitis B virus-induced cirrhosis (50%). The mean liver stiffness value 
with transient elastography was 6.1 ± 3.0 kPa, and the mean magnetic resonance elastography value was 2.7 ± 1.0 kPa. A significant 
positive correlation was found between magnetic resonance elastography and transient elastography in terms of liver stiffness measurement (r = 0.61, P < .001). Obesity and the underlying etiology of liver diseases did not have any significant negative effect on magnetic resonance elastography and transient elastography measurements. During the follow-up, the post-transplant recurrence rates 
of hepatic steatosis and hepatic fibrosis were 26% and 37%, respectively. The recurrence rates of post-transplant hepatic steatosis 
and liver fibrosis were slightly higher in recipients with non-alcoholic fatty liver disease-related cirrhosis than those with viral hepatitisrelated etiologies (44% vs 27%, P = .43; 44% vs 30%, P = .45, respectively).
Conclusion: Magnetic resonance elastography and transient elastography are accurate in assessing liver fibrosis in the liver transplant 
setting. Obesity and the underlying etiology of primary liver disease do not influence the measurements
AU  - KARTAL, Aysun
AU  - Idilman, Ilkay
AU  - balaban, hatice yasemin
AU  - Özkan, Hasan
AU  - ELHAN, ATİLLA HALİL
AU  - Melekoğlu Ellik, Zeynep
AU  - Karcaaltincaba, Musturay
AU  - Idilman, Ramazan
DO  - 10.5152/tjg.2022.21705
PY  - 2022
JO  - Turkish Journal of Gastroenterology
VL  - 33
IS  - 2
SN  - 1300-4948
SP  - 153
EP  - 160
DB  - TRDizin
UR  - http://search/yayin/detay/524303
ER  -