The relationship between pulmonary function tests, thorax HRCT, and quantitative ventilation-perfusion scintigraphy in chronic obstructive pulmonary disease

Mutlu, Birsen; İKİTİMUR, HANDE; DEMİR, Tunçalp; TEKGÜNDÜZ, Akpınar Sibel; ÖZMEN, ÖZLEM; YILDIRIM, Nurhayat; AKMAN, Canan; KANMAZ, Bedii

The relationship between pulmonary function tests, thorax HRCT, and quantitative ventilation-perfusion scintigraphy in chronic obstructive pulmonary disease

Tunçalp DEMİR, (İstanbul Üniversitesi, Cerrahpaşa Tıp Fakültesi, Göğüs Hastalıkları Anabilim Dalı, İstanbul, Türkiye)

Hande İKİTİMUR, (İstanbul Üniversitesi, Cerrahpaşa Tıp Fakültesi, Göğüs Hastalıkları Anabilim Dalı, İstanbul, Türkiye)

Akpınar Sibel TEKGÜNDÜZ, (İstanbul Üniversitesi, Cerrahpaşa Tıp Fakültesi, Göğüs Hastalıkları Anabilim Dalı, İstanbul, Türkiye)

Birsen MUTLU, (İstanbul Üniversitesi, Cerrahpaşa Tıp Fakültesi, Göğüs Hastalıkları Anabilim Dalı, İstanbul, Türkiye)

Nurhayat YILDIRIM, (İstanbul Üniversitesi, Cerrahpaşa Tıp Fakültesi, Göğüs Hastalıkları Anabilim Dalı, İstanbul, Türkiye)

Canan AKMAN, (İstanbul Üniversitesi, Cerrahpaşa Tıp Fakültesi, Göğüs Radyolojisi Anabilim Dalı, İstanbul, Türkiye)

Özlem ÖZMEN, (İstanbul Üniversitesi, Cerrahpaşa Tıp Fakültesi, Nükleer Tıp Anabilim Dalı, İstanbul, Türkiye)

Bedii KANMAZ (İstanbul Üniversitesi, Cerrahpaşa Tıp Fakültesi, Nükleer Tıp Anabilim Dalı, İstanbul, Türkiye)

Tüberküloz ve Toraks

4 0

Yıl: 2005 Cilt: 53 Sayı: 4 Sayfa Aralığı: 347 - 353 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

The relationship between pulmonary function tests, thorax HRCT, and quantitative ventilation-perfusion scintigraphy in chronic obstructive pulmonary disease

Öz:

Çalışmamızda yaş ortalamaları 65.6 ± 5.5 yıl olan 16 kronik obstrüktif akciğer hastalığı (KOAH) olan erkek olguda, solunum fonksiyon testleri, toraks yüksek rezolüsyonlu bilgisayarlı tomografi (YRBT) incelemesi ve kantitatif ventilasyon-perfüzyon(V/Q) sintigrafisi arasındaki ilişki incelenmiştir. Olguların ortalama FVC değeri 2352 ± 642 mL (%65.4 ± 15.8), FEV1değeri 1150 ± 442 mL (%40.8 ± 14.9), DLCO/VA değeri 3.17 ± 0.88 mL/dakika/mmHg/L, PaO2 ve PaCO2 değerleri sırasıyla 68.5 ± 11.04 mmHg, 38.9 ± 5.8 mmHg idi. Her hastanın toraks YRBT ve V/Q sintigrafi imajları, sağ ve sol akciğerde üst,orta ve alt alanlara bölünerek incelenmiştir. Toraks YRBT’de amfizem skorlaması için Visual skorlama yöntemi kullanılmış ve bu yöntemle amfizem derecesi hafiften ağıra doğru skorlanmıştır ($leq$ %25 - $geq$ %76). Amfizem skorlarının her iki akciğerinüst alanlarında en yüksek olduğu, aynı alanlarda V/Q oranlarının da en düşük olduğu bulunmuştur. DLCO/VA, DLCOdeğerleri ile total amfizem skoru ve üst, orta, alt akciğer alanlardaki amfizem skorları arasında korelasyon tespit edilmiştir. Çalışmamızda; KOAH’lı olgularda amfizematöz değişikliklerin üst akciğer alanlarında daha belirgin olduğunu ve aynı alanlarda V/Q oranının en düşük olduğunu saptadık.

Anahtar Kelime: Ventilasyon-perfüzyon oranı Tomografi, x-ışınlı bilgisayarlı Solunum fonksiyon testleri Akciğer hastalığı, kronik obstrüktif Radyonüklid görüntüleme

Konular: Solunum Sistemi Kulak, Burun, Boğaz

Kronik obstrüktif akciğer hastalığı olgularında solunum fonksiyon testleri, toraks YRBT ve kantitatif ventilasyon-perfüzyon sintigrafisi arasındaki ilişki

Öz:

We have evaluated the relationship between pulmonary function tests (PFT), thorax high resolution computed tomography(HRCT) images and quantitative ventilation-perfusion (V/Q) scintigraphic studies in 16 male patients (mean age 65.6 ± 5.5years) with chronic obstructive pulmonary disease (COPD). The mean forced vital capacity (FVC) value of the patient groupwas 2352 ± 642 mL (65.4 ± 15.8%), whereas mean forced expiratory volume in one second (FEV1) was found to be 1150± 442 mL (40.8 ± 14.9%). The ratio of carbon monoxide diffusion capacity to alveolar ventilation (DLCO/VA) was 3.17 ± 0.88mL/min/mmHg/L, and the mean partial oxygen (PaO2) and carbon dioxide (PaCO2) pressures were 68.5 ± 11.04 mmHgand 38.9 ± 5.8 mmHg respectively. For each patient, thorax HRCT and V/Q scintigraphic images of both lungs were dividedinto upper, mid and lower zones during examination. Visual scoring for the assessment of emphysema on thorax HRCTwere used and images were graded from mild to severe ($leq$25%- $geq$76%). Emphysema scores were found to be higher on upperzones with accompanying lowest V/Q ratios. DLCO/VA, DLCO, total emphysema scores, and individual emphysemascores of the upper, mid and lower zones were found to be correlated. As a conclusion, it can be stated that emphysematouschanges in COPD patients are more apparent in the upper lung zones, which also have the lowest V/Q ratios.

Anahtar Kelime: Respiratory Function Tests Pulmonary Disease, Chronic Obstructive Radionuclide Imaging Ventilation-Perfusion Ratio Tomography, X-Ray Computed

Konular: Solunum Sistemi Kulak, Burun, Boğaz

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Bibliyografik

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APA	DEMİR T, İKİTİMUR H, TEKGÜNDÜZ A, Mutlu B, YILDIRIM N, AKMAN C, ÖZMEN Ö, KANMAZ B (2005). The relationship between pulmonary function tests, thorax HRCT, and quantitative ventilation-perfusion scintigraphy in chronic obstructive pulmonary disease. , 347 - 353.
Chicago	DEMİR Tunçalp,İKİTİMUR HANDE,TEKGÜNDÜZ Akpınar Sibel,Mutlu Birsen,YILDIRIM Nurhayat,AKMAN Canan,ÖZMEN ÖZLEM,KANMAZ Bedii The relationship between pulmonary function tests, thorax HRCT, and quantitative ventilation-perfusion scintigraphy in chronic obstructive pulmonary disease. (2005): 347 - 353.
MLA	DEMİR Tunçalp,İKİTİMUR HANDE,TEKGÜNDÜZ Akpınar Sibel,Mutlu Birsen,YILDIRIM Nurhayat,AKMAN Canan,ÖZMEN ÖZLEM,KANMAZ Bedii The relationship between pulmonary function tests, thorax HRCT, and quantitative ventilation-perfusion scintigraphy in chronic obstructive pulmonary disease. , 2005, ss.347 - 353.
AMA	DEMİR T,İKİTİMUR H,TEKGÜNDÜZ A,Mutlu B,YILDIRIM N,AKMAN C,ÖZMEN Ö,KANMAZ B The relationship between pulmonary function tests, thorax HRCT, and quantitative ventilation-perfusion scintigraphy in chronic obstructive pulmonary disease. . 2005; 347 - 353.
Vancouver	DEMİR T,İKİTİMUR H,TEKGÜNDÜZ A,Mutlu B,YILDIRIM N,AKMAN C,ÖZMEN Ö,KANMAZ B The relationship between pulmonary function tests, thorax HRCT, and quantitative ventilation-perfusion scintigraphy in chronic obstructive pulmonary disease. . 2005; 347 - 353.
IEEE	DEMİR T,İKİTİMUR H,TEKGÜNDÜZ A,Mutlu B,YILDIRIM N,AKMAN C,ÖZMEN Ö,KANMAZ B "The relationship between pulmonary function tests, thorax HRCT, and quantitative ventilation-perfusion scintigraphy in chronic obstructive pulmonary disease." , ss.347 - 353, 2005.
ISNAD	DEMİR, Tunçalp vd. "The relationship between pulmonary function tests, thorax HRCT, and quantitative ventilation-perfusion scintigraphy in chronic obstructive pulmonary disease". (2005), 347-353.

APA	DEMİR T, İKİTİMUR H, TEKGÜNDÜZ A, Mutlu B, YILDIRIM N, AKMAN C, ÖZMEN Ö, KANMAZ B (2005). The relationship between pulmonary function tests, thorax HRCT, and quantitative ventilation-perfusion scintigraphy in chronic obstructive pulmonary disease. Tüberküloz ve Toraks, 53(4), 347 - 353.
Chicago	DEMİR Tunçalp,İKİTİMUR HANDE,TEKGÜNDÜZ Akpınar Sibel,Mutlu Birsen,YILDIRIM Nurhayat,AKMAN Canan,ÖZMEN ÖZLEM,KANMAZ Bedii The relationship between pulmonary function tests, thorax HRCT, and quantitative ventilation-perfusion scintigraphy in chronic obstructive pulmonary disease. Tüberküloz ve Toraks 53, no.4 (2005): 347 - 353.
MLA	DEMİR Tunçalp,İKİTİMUR HANDE,TEKGÜNDÜZ Akpınar Sibel,Mutlu Birsen,YILDIRIM Nurhayat,AKMAN Canan,ÖZMEN ÖZLEM,KANMAZ Bedii The relationship between pulmonary function tests, thorax HRCT, and quantitative ventilation-perfusion scintigraphy in chronic obstructive pulmonary disease. Tüberküloz ve Toraks, vol.53, no.4, 2005, ss.347 - 353.
AMA	DEMİR T,İKİTİMUR H,TEKGÜNDÜZ A,Mutlu B,YILDIRIM N,AKMAN C,ÖZMEN Ö,KANMAZ B The relationship between pulmonary function tests, thorax HRCT, and quantitative ventilation-perfusion scintigraphy in chronic obstructive pulmonary disease. Tüberküloz ve Toraks. 2005; 53(4): 347 - 353.
Vancouver	DEMİR T,İKİTİMUR H,TEKGÜNDÜZ A,Mutlu B,YILDIRIM N,AKMAN C,ÖZMEN Ö,KANMAZ B The relationship between pulmonary function tests, thorax HRCT, and quantitative ventilation-perfusion scintigraphy in chronic obstructive pulmonary disease. Tüberküloz ve Toraks. 2005; 53(4): 347 - 353.
IEEE	DEMİR T,İKİTİMUR H,TEKGÜNDÜZ A,Mutlu B,YILDIRIM N,AKMAN C,ÖZMEN Ö,KANMAZ B "The relationship between pulmonary function tests, thorax HRCT, and quantitative ventilation-perfusion scintigraphy in chronic obstructive pulmonary disease." Tüberküloz ve Toraks, 53, ss.347 - 353, 2005.
ISNAD	DEMİR, Tunçalp vd. "The relationship between pulmonary function tests, thorax HRCT, and quantitative ventilation-perfusion scintigraphy in chronic obstructive pulmonary disease". Tüberküloz ve Toraks 53/4 (2005), 347-353.