Fungal culture results and clinical effects of bronchoscopy specimens
Yıl: 2022 Cilt: 70 Sayı: 1 Sayfa Aralığı: 15 - 26 Metin Dili: İngilizce DOI: 10.5578/tt.20229903 İndeks Tarihi: 29-06-2022
Fungal culture results and clinical effects of bronchoscopy specimens
Öz: Introduction: Early isolation of the fungal pathogen and early initiation of
treatment affect mortality and morbidity rates. The purpose of this study was
to reveal the frequency of determination of fungal pathogens in bronchoscopy
unit patients.
Materials and Methods: The study was designed retrospectively. All patients
who underwent bronchoscopy for any reason were enrolled. The patients with
suspected fungal infection were divided into three groups after the procedure:
1) Proven fungal infection,
2) Colonization,
3) Without infection.
Results: One thousand one hundred and twenty-eight patients were included
in the study. Fungal infection was suspected in 188 (16.7%) patients before
bronchoscopy. After the examination of the bronchoscopic materials, it was
determined that 59 (5.2%) patients had proven fungal infection, 148 (13.1%)
patients had colonization, and 921 (81.7%) patients did not have fungal infection.
The radiological findings of the patients that were indicative of fungal
infection before bronchoscopy were observed as consolidation in 391
(34.7%) and nodule in 413 (36.6%). Fungal growth in bronchoscopic cultures
was found in 186 (16.4%) patients, and the most common fungus was
Candida albicans (C. albicans) in 110 (9.7%). The treatment was not changed
according to the culture results in the patients. No treatment was initiated in
the other 108 (98.2%) patients with C. albicans. One hundred and sixty-five
(88%) of all fungal growths were detected in the BAL/bronchial lavage fluid.
While 29 (45%) of them had not received antifungal treatment before, antifungal
treatment was started after bronchoscopy.
Conclusion: C. albicans was isolated the most among all bacterial and fungal
agents in all patient groups that were immunosuppressed or not at a routine
bronchoscopy unit. Diagnostic bronchoscopic sampling should be performed
at the early stages of clinically or radiologically suspected fungal illness.
Anahtar Kelime: Bronkoskopi örneklerinin mantar kültür sonuçları ve klinik etkileri
Öz: Giriş: Fungal patojenin erken izolasyonu ve tedaviye erken başlanması mortalite ve morbidite oranlarını etkiler. Bu çalışmanın amacı,
bronkoskopi ünitesi hastalarında fungal patojenlerin saptanma sıklığını ortaya koymaktır.
Materyal ve Metod: Çalışma retrospektif olarak tasarlandı. Herhangi bir nedenle bronkoskopi yapılan tüm hastalar çalışmaya alındı.
İşlem sonrası mantar enfeksiyonu şüphesi olan hastalar üç gruba ayrıldı:
1) Kanıtlanmış mantar enfeksiyonu,
2) Kolonizasyon,
3) Enfeksiyon yok.
Bulgular: Bin yüz yirmi sekiz hasta çalışmaya dahil edildi. Bronkoskopi öncesi 188 (%16.7) hastada mantar enfeksiyonundan şüphelenildi.
Bronkoskopi öncesi fungal enfeksiyon belirtisi olan hastaların radyolojik bulguları 391'inde (%34.7) konsolidasyon, 413'ünde
(%36.6) nodül olarak izlendi. Bronkoskopik materyallerin incelenmesi sonucunda 59 (%5.2) hastada kanıtlanmış mantar enfeksiyonu,
148 (%13.1) hastada kolonizasyon ve 921 (%81.7) hastada fungal enfeksiyon olmadığı belirlendi. Bronkoskopik kültürlerde
mantar üremesi 186 (%16.4) hastada saptandı ve en sık görülen mantar 110 (%9.7) hastada Candida albicans (C. albicans) idi.
Hastalarda kültür sonuçlarına göre tedavi değiştirilmedi. C. albicans’lı diğer 108 (%98.2) hastada ise herhangi bir tedavi uygulanmadı.
Tüm mantar üremelerinin 165’i (%88) BAL/bronş lavajı sıvısında saptandı, 29’u (%45) daha önce antifungal tedavi almamışken,
bronkoskopi sonrası antifungal tedavi başlandı.
Sonuç: Rutin bronkoskopi ünitesinde immünsüprese olan veya olmayan tüm hasta gruplarında bakteriyel ve fungal etkenler arasında en
fazla C. albicans izole edildi. Tanısal bronkoskopik örnekleme, klinik veya radyolojik olarak şüpheli mantar hastalığının erken evrelerinde
yapılmalıdır.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | AYÇIÇEK O, PEHLİVANLAR KÜÇÜK M, Koc I, Ayaydın Mürtezaoğlu S, Pehlivanlar A, Öztuna F, OZLÜ T (2022). Fungal culture results and clinical effects of bronchoscopy specimens. , 15 - 26. 10.5578/tt.20229903 |
| Chicago | AYÇIÇEK OLCAY,PEHLİVANLAR KÜÇÜK Mehtap,Koc Ilknur,Ayaydın Mürtezaoğlu Sevil,Pehlivanlar Ayşegül,Öztuna Funda,OZLÜ TEVFIK Fungal culture results and clinical effects of bronchoscopy specimens. (2022): 15 - 26. 10.5578/tt.20229903 |
| MLA | AYÇIÇEK OLCAY,PEHLİVANLAR KÜÇÜK Mehtap,Koc Ilknur,Ayaydın Mürtezaoğlu Sevil,Pehlivanlar Ayşegül,Öztuna Funda,OZLÜ TEVFIK Fungal culture results and clinical effects of bronchoscopy specimens. , 2022, ss.15 - 26. 10.5578/tt.20229903 |
| AMA | AYÇIÇEK O,PEHLİVANLAR KÜÇÜK M,Koc I,Ayaydın Mürtezaoğlu S,Pehlivanlar A,Öztuna F,OZLÜ T Fungal culture results and clinical effects of bronchoscopy specimens. . 2022; 15 - 26. 10.5578/tt.20229903 |
| Vancouver | AYÇIÇEK O,PEHLİVANLAR KÜÇÜK M,Koc I,Ayaydın Mürtezaoğlu S,Pehlivanlar A,Öztuna F,OZLÜ T Fungal culture results and clinical effects of bronchoscopy specimens. . 2022; 15 - 26. 10.5578/tt.20229903 |
| IEEE | AYÇIÇEK O,PEHLİVANLAR KÜÇÜK M,Koc I,Ayaydın Mürtezaoğlu S,Pehlivanlar A,Öztuna F,OZLÜ T "Fungal culture results and clinical effects of bronchoscopy specimens." , ss.15 - 26, 2022. 10.5578/tt.20229903 |
| ISNAD | AYÇIÇEK, OLCAY vd. "Fungal culture results and clinical effects of bronchoscopy specimens". (2022), 15-26. https://doi.org/10.5578/tt.20229903 |
| APA | AYÇIÇEK O, PEHLİVANLAR KÜÇÜK M, Koc I, Ayaydın Mürtezaoğlu S, Pehlivanlar A, Öztuna F, OZLÜ T (2022). Fungal culture results and clinical effects of bronchoscopy specimens. Tüberküloz ve Toraks, 70(1), 15 - 26. 10.5578/tt.20229903 |
| Chicago | AYÇIÇEK OLCAY,PEHLİVANLAR KÜÇÜK Mehtap,Koc Ilknur,Ayaydın Mürtezaoğlu Sevil,Pehlivanlar Ayşegül,Öztuna Funda,OZLÜ TEVFIK Fungal culture results and clinical effects of bronchoscopy specimens. Tüberküloz ve Toraks 70, no.1 (2022): 15 - 26. 10.5578/tt.20229903 |
| MLA | AYÇIÇEK OLCAY,PEHLİVANLAR KÜÇÜK Mehtap,Koc Ilknur,Ayaydın Mürtezaoğlu Sevil,Pehlivanlar Ayşegül,Öztuna Funda,OZLÜ TEVFIK Fungal culture results and clinical effects of bronchoscopy specimens. Tüberküloz ve Toraks, vol.70, no.1, 2022, ss.15 - 26. 10.5578/tt.20229903 |
| AMA | AYÇIÇEK O,PEHLİVANLAR KÜÇÜK M,Koc I,Ayaydın Mürtezaoğlu S,Pehlivanlar A,Öztuna F,OZLÜ T Fungal culture results and clinical effects of bronchoscopy specimens. Tüberküloz ve Toraks. 2022; 70(1): 15 - 26. 10.5578/tt.20229903 |
| Vancouver | AYÇIÇEK O,PEHLİVANLAR KÜÇÜK M,Koc I,Ayaydın Mürtezaoğlu S,Pehlivanlar A,Öztuna F,OZLÜ T Fungal culture results and clinical effects of bronchoscopy specimens. Tüberküloz ve Toraks. 2022; 70(1): 15 - 26. 10.5578/tt.20229903 |
| IEEE | AYÇIÇEK O,PEHLİVANLAR KÜÇÜK M,Koc I,Ayaydın Mürtezaoğlu S,Pehlivanlar A,Öztuna F,OZLÜ T "Fungal culture results and clinical effects of bronchoscopy specimens." Tüberküloz ve Toraks, 70, ss.15 - 26, 2022. 10.5578/tt.20229903 |
| ISNAD | AYÇIÇEK, OLCAY vd. "Fungal culture results and clinical effects of bronchoscopy specimens". Tüberküloz ve Toraks 70/1 (2022), 15-26. https://doi.org/10.5578/tt.20229903 |
