TY  - JOUR
TI  - Anticholinergic Syndrome Due
to the Use of Datura Stramonium
Seeds for Constipation: A Story of
Prolonged ICU Stay
AB  - Datura stramonium is grown widely in some regions of Turkey. Datura stramonium seed is used in the treatment
of various diseases such as constipation and acne and causes anticholinergic toxicity when taken in overdose.
In the literature, patients presenting with mild symptoms are the majority, and intensive care follow-up is
often not required for these patients. In this case report, we present a 50-year-old male patient who received
around 200 Datura stramonium seeds for the treatment of chronic constipation. When the patient admitted
to the emergency department, he was unconscious, and his pupils were dilated. The patient who had severe
vomiting and contractions was intubated. With the diagnosis of anticholinergic syndrome, physostigmine 0.5
mg (one dose) and 1 mg (two times) were administered to the patient with central nervous system findings.
The patient who developed sepsis due to aspiration pneumonia during the follow-up stayed in the intensive
care unit for 40 days with the support of mechanical ventilator for 37 days. The patient was discharged after
26 days of treatment in the physical therapy service. Accidental ingestion of Datura stramonium seed used
for herbal therapy in high doses may cause life-threatening consequences due to its anticholinergic effects or
complications related to these effects.
AU  - BULUT, Kadir
AU  - ertürk, ayşim
AU  - Yesiltepe, Ali
AU  - Sungur, Murat
AU  - KAYAALTI, Selda
AU  - Gündoğan, Kürşat
AU  - Temel, Şahin
DO  - 10.37678/dcybd.2021.2673
PY  - 2021
JO  - Journal of critical and intensive care (Online)
VL  - 12
IS  - 3
SN  - 2717-6428
SP  - 99
EP  - 101
DB  - TRDizin
UR  - http://search/yayin/detay/528252
ER  -