Yıl: 2022 Cilt: 11 Sayı: 2 Sayfa Aralığı: 457 - 461 Metin Dili: İngilizce DOI: 10.5455/medscience.2021.07.237 İndeks Tarihi: 04-07-2022

Prediction of mortality at first admission in COVID-19 pneumonia: A retrospective cohort study

Öz:
The Coronovirus-19 (COVID-19) pandemic that started in Wuhan, China, at the end of 2019 may cause severe acute respiratory syndrome in some patients. We aimed to investigate the factors that can provide admission mortality prediction in patients with a definite diagnosis of COVID-19. We included patients with radiologically confirmed COVID-19 pneumonia with any significant comorbidities between February 2020-May 2020. We included 129 patients with a mean age of 58 ±15.3 years (range 16-88), 74 (57.4%) men, and of which 27 (21%) died in hospital. Age, aspartate aminotransferase (AST), gamma-glutamyltranspeptidase (GGT), albumin, international normalization ratio (INR), C-reactive protein (CRP), ferritin, d-dimer, and leukocyte levels differed between those who survived and died in the hospital. Multivariable regression showed increased odds of in-hospital death associated with older age (odds ratio 1.09 95% Confidence Interval [CI] (1.021-1.169; p=0.01), and ferritin 1.003 (1.001-1.004; p<0.001) which could help clinicians to identify patients with poor prognosis at an early stage. The area under the receiver operating characteristic curve was 0.886 (95% CI, 0.811-0.939; p<0.0001) for ferritin and 0.763 (95% CI, 0.673-0.85; p<0.0001) for age in differentiating between survived and died in-hospital patients with cutoffs >289,1 ng/mL and >51 years, respectively. Elevated ferritin and advanced age significantly predicted mortality at the first admission in COVID-19 infection. A ferritin cutoff >289 ng/mL had a 100% negative predictive value to differentiate surviving from in-hospital dead patients.
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APA Köker İ, Yurtsever İ, uysal ö, HÜSEYNOV N, Senturk H (2022). Prediction of mortality at first admission in COVID-19 pneumonia: A retrospective cohort study. , 457 - 461. 10.5455/medscience.2021.07.237
Chicago Köker İbrahim Hakkı,Yurtsever İsmail,uysal ömer,HÜSEYNOV NURLAN,Senturk Hakan Prediction of mortality at first admission in COVID-19 pneumonia: A retrospective cohort study. (2022): 457 - 461. 10.5455/medscience.2021.07.237
MLA Köker İbrahim Hakkı,Yurtsever İsmail,uysal ömer,HÜSEYNOV NURLAN,Senturk Hakan Prediction of mortality at first admission in COVID-19 pneumonia: A retrospective cohort study. , 2022, ss.457 - 461. 10.5455/medscience.2021.07.237
AMA Köker İ,Yurtsever İ,uysal ö,HÜSEYNOV N,Senturk H Prediction of mortality at first admission in COVID-19 pneumonia: A retrospective cohort study. . 2022; 457 - 461. 10.5455/medscience.2021.07.237
Vancouver Köker İ,Yurtsever İ,uysal ö,HÜSEYNOV N,Senturk H Prediction of mortality at first admission in COVID-19 pneumonia: A retrospective cohort study. . 2022; 457 - 461. 10.5455/medscience.2021.07.237
IEEE Köker İ,Yurtsever İ,uysal ö,HÜSEYNOV N,Senturk H "Prediction of mortality at first admission in COVID-19 pneumonia: A retrospective cohort study." , ss.457 - 461, 2022. 10.5455/medscience.2021.07.237
ISNAD Köker, İbrahim Hakkı vd. "Prediction of mortality at first admission in COVID-19 pneumonia: A retrospective cohort study". (2022), 457-461. https://doi.org/10.5455/medscience.2021.07.237
APA Köker İ, Yurtsever İ, uysal ö, HÜSEYNOV N, Senturk H (2022). Prediction of mortality at first admission in COVID-19 pneumonia: A retrospective cohort study. Medicine Science, 11(2), 457 - 461. 10.5455/medscience.2021.07.237
Chicago Köker İbrahim Hakkı,Yurtsever İsmail,uysal ömer,HÜSEYNOV NURLAN,Senturk Hakan Prediction of mortality at first admission in COVID-19 pneumonia: A retrospective cohort study. Medicine Science 11, no.2 (2022): 457 - 461. 10.5455/medscience.2021.07.237
MLA Köker İbrahim Hakkı,Yurtsever İsmail,uysal ömer,HÜSEYNOV NURLAN,Senturk Hakan Prediction of mortality at first admission in COVID-19 pneumonia: A retrospective cohort study. Medicine Science, vol.11, no.2, 2022, ss.457 - 461. 10.5455/medscience.2021.07.237
AMA Köker İ,Yurtsever İ,uysal ö,HÜSEYNOV N,Senturk H Prediction of mortality at first admission in COVID-19 pneumonia: A retrospective cohort study. Medicine Science. 2022; 11(2): 457 - 461. 10.5455/medscience.2021.07.237
Vancouver Köker İ,Yurtsever İ,uysal ö,HÜSEYNOV N,Senturk H Prediction of mortality at first admission in COVID-19 pneumonia: A retrospective cohort study. Medicine Science. 2022; 11(2): 457 - 461. 10.5455/medscience.2021.07.237
IEEE Köker İ,Yurtsever İ,uysal ö,HÜSEYNOV N,Senturk H "Prediction of mortality at first admission in COVID-19 pneumonia: A retrospective cohort study." Medicine Science, 11, ss.457 - 461, 2022. 10.5455/medscience.2021.07.237
ISNAD Köker, İbrahim Hakkı vd. "Prediction of mortality at first admission in COVID-19 pneumonia: A retrospective cohort study". Medicine Science 11/2 (2022), 457-461. https://doi.org/10.5455/medscience.2021.07.237