TY  - JOUR
TI  - Pharmacotherapy and Nursing Approaches in Neonates
AB  - Pharmacotherapy gains importance in newborns due to the differences in body physiology.
Newborns need special drug treatments due to their anatomical, physiological, and
biochemical differences that change the pharmacokinetics and pharmacodynamics of various
drugs. Factors such as gastric pH and emptying time, intestinal transit time, immaturity
of secretion, total body water, immaturity of the neurological and the urinary systems
may result in age-related changes in pharmacokinetics and pharmacodynamics. Due to the
immaturity of the body systems of the newborns, the absorption, distribution, metabolism,
and excretion of the drugs from the body are different from that in adults. Knowing the
pharmacokinetics of the drugs in medicaments and their appropriate treatment is of great
importance in the prevention of drug errors. From these perspectives, neonatology nurses
have crucial roles to play in providing patient safety in their care. The aim of this review
is to develop a guide regarding the essential principles of pharmacokinetics in newborns
and safe drug administrations. In this review, the newborn pharmacokinetics and nursing
approaches are examined under three subtitles: (1) pharmacological definitions-principles,
(2) pharmacokinetics in newborns, and (3) responsibilities of the nurse. It is expected that
this study will guide neonatal nurses in practice and shed light for further research and new
studies on pharmacotherapy and safe drug administrations.
AU  - Altay, Naime
AU  - SARI, ÇİĞDEM
DO  - 10.5152/jern.2022.83704
PY  - 2022
JO  - Journal of education and research in nursing (Online)
VL  - 19
IS  - 2
SN  - 2757-9204
SP  - 250
EP  - 256
DB  - TRDizin
UR  - http://search/yayin/detay/529798
ER  -