TY  - JOUR
TI  - Comparison of Serum Adropin Levels in Patients with Diabetes Mellitus,
COVID-19, and COVID-19 with Diabetes Mellitus
AB  - Objective: In the present study, the relationship between a poor prognosis and adropin levels in diabetic
patients with coronavirus disease 2019 was investigated by measuring serum adropin levels and levels of
D-dimer, C-reactive protein, and ferritin, which are considered prognostic factors for coronavirus disease
2019.
Materials and Methods: Hundred volunteer participants treated in the Erzurum Regional Training and
Research Hospital were included in this study. Serum adropin levels were measured by enzyme-linked
immunosorbent
assay. The relationship between serum adropin level and C-reactive protein, ferritin, and
D-dimer levels was analyzed by correlation analysis.
Results: The participants’ serum adropin levels differed between the groups (P = .0007). The control group
had the highest adropin levels among groups. The lowest adropin levels were in the COVID + diabetes mellitus
group. Adropin levels of diabetes mellitus, COVID, and diabetes mellitus + COVID groups were significantly
decreased when compared to the control (P < .05). There was a significant negative correlation
between adropin and C-reactive protein, D-dimer, and ferritin.
Conclusion: Adropin can be used as an auxiliary biomarker, a prognostic factor in the early management of
coronavirus disease 2019 patients with diabetes mellitus. We think that our study will guide future studies
conducted in this field.
AU  - Bilen, Arzu
AU  - OZDEN, AYSE
AU  - KARABULUT UZUNÇAKMAK, SEVGİ
AU  - Tor, Ibrahim Hakki
AU  - Aydın, Pelin
DO  - 10.5152/eurasianjmed.2022.22128
PY  - 2022
JO  - Eurasian Journal of Medicine
VL  - 54
IS  - 2
SN  - 1308-8734
SP  - 197
EP  - 201
DB  - TRDizin
UR  - http://search/yayin/detay/530194
ER  -