TY  - JOUR
TI  - A Comparison of Automated Segmentation and 
Manual Tracing of Magnetic Resonance Imaging
to Quantify Lateral Ventricle Volumes
AB  - Objective: Ventricular volume measurements have been proposed as a useful biomarker for several neurological diseases. 
The goal of this study was to compare the performance of 3 fully-automated tools, volBrain (http://volbrain.upv.es), ALVIN 
(Automatic Lateral Ventricle Delineation) (https://sites.google.com/site/mrilateralventricle/), and MRICloud (http://mricloud.org), with expert hand tracing to quantify lateral ventricle (LV) volume using magnetic resonance images.
Materials and Methods: The sample comprised 24 healthy subjects (age: 25.1±5.7 years, all male). Volumes derived from 
each automated measurement were compared to hand tracing results performed by 2 specialists to assess the percent volume 
difference using the intraclass correlation coefficient (ICC), concordance correlation coefficient (CCC), Dice index value, and 
Bland-Altman analysis.
Results: The ICC agreement of the Manual_1 and Manual_2 was very good (0.979), and there was no statistically significant 
difference (p>0.001). The volume difference of all methods was similar. The CCC with MRICloud and ALVIN was higher than 
that of volBrain. Bland-Altman plots indicated that the 3 automated methods demonstrated acceptable agreement.
Conclusion: Compared with hand tracing, the LV volumes generated by MRICloud were more accurate than those of 
volBrain and ALVIN. LV volume values can provide valuable data related to the volumetric dependencies of the anatomical 
structures in various clinical conditions that can now be easily obtained using automated tools.
AU  - akkus yetkin, esra
AU  - Değirmencioğlu, Levent
AU  - Bastepe-Gray, Serap
AU  - Kamaşak Arpaçay, BURCU
AU  - Ilica, A. Turan
AU  - Karapınar, Burak Oğuzhan
AU  - IPEKTEN, Funda
AU  - ACER, Niyazi
DO  - 10.14744/etd.2021.73920
PY  - 2022
JO  - Erciyes Medical Journal
VL  - 44
IS  - 2
SN  - 2149-2247
SP  - 148
EP  - 155
DB  - TRDizin
UR  - http://search/yayin/detay/530625
ER  -