The adequacy of current diagnostic criteria for
making a diagnosis of ABPA

ÇETİN, gülden; Yilmaz, Insu; Türk, Murat; nazik bahçecioğlu, sakine

doi:10.5578/tt.20229804

The adequacy of current diagnostic criteria for making a diagnosis of ABPA

Murat TÜRK, (Kayseri Şehir Hastanesi, Göğüs Hastalıkları Kliniği, Klinik İmmünoloji ve Alerji Birimi, Kayseri, Türkiye, Erciyes Üniversitesi Tıp Fakültesi, Göğüs Hastalıkları Anabilim Dalı, Klinik İmmünoloji ve Alerji Bilim Dalı, Kayseri, Türkiye)

Gülden PAÇACI ÇETİN, (Erciyes Üniversitesi Tıp Fakültesi, Göğüs Hastalıkları Anabilim Dalı, Klinik İmmünoloji ve Alerji Bilim Dalı, Kayseri, Türkiye)

İnsu YILMAZ, (Erciyes Üniversitesi Tıp Fakültesi, Göğüs Hastalıkları Anabilim Dalı, Klinik İmmünoloji ve Alerji Bilim Dalı, Kayseri, Türkiye)

Sakine BAHÇECİOĞLU (Atatürk Göğüs Hastalıkları ve Göğüs Cerrahisi Eğitim ve Araştırma Hastanesi, İmmünoloji ve Alerji Hastalıkları Kliniği, Ankara, Türkiye)

Tüberküloz ve Toraks

4 1

Yıl: 2022 Cilt: 70 Sayı: 2 Sayfa Aralığı: 141 - 148 Metin Dili: İngilizce DOI: 10.5578/tt.20229804 İndeks Tarihi: 06-07-2022

The adequacy of current diagnostic criteria for making a diagnosis of ABPA

Öz:

Introduction: Currently, there are four different diagnostic criteria systems for allergic bronchopulmonary aspergillosis (ABPA): The Rosenberg-Patterson, Seropositive ABPA (ABPA-S), Central Bronchiectasis and ABPA (ABPA-CB), and the International Society for Human and Animal Mycology (ISHAM) ABPA study group criteria. This study aims to retrospectively compare these four diagnostic criteria in ABPA patients. Materials and Methods: Patients who were followed up with the diagnosis of ABPA were retrospectively re-evaluated using these four diagnostic criteria, and the superiority of these criteria to each other was determined. Results: A total of 10 ABPA patients were included in the study. Seven patients were diagnosed according to ISHAM ABPA study group diagnostic criteria and six patients according to the Rosenberg-Patterson diagnostic criteria. None of the patients fulfilled the criteria when evaluated individually with ABPA-S and ABPA-CB. Of patients diagnosed by ISHAM, five had a total IgE level above 1000 IU/mL and two had below 1000 IU/mL. Conclusion: We demonstrated that the diagnostic criteria developed by the ISHAM ABPA study group were superior to the others in diagnosing ABPA in cases with a total IgE level above 1000 IU/mL. However, all these criteria seem to be sufficient to diagnose ABPA in patients with a total IgE below 1000 IU/mL. We believe the necessity to demonstrate presence of Aspergillus fumigatus precipitating antibodies or specific IgG positivity should be questioned particularly in patients with radiologic findings compatible with ABPA and a total IgE level below 1000 IU/mL.

Anahtar Kelime:

ABPA tanısında güncel tanısal kriterler yeterli midir?

Öz:

Giriş: Alerjik bronkopulmoner aspergilloz (ABPA) için dört farklı tanı kriter sistemi bulunmaktadır: Rosenberg-Patterson, Seropozitif ABPA (ABPA-S), Santral Bronşektazi-ABPA (ABPA-CB) ve Uluslararası İnsan ve Hayvan Mikolojisi Derneği (International Society for Human and Animal Mycology: ISHAM) ABPA çalışma grubu kriterleri. Bu çalışma, ABPA hastalarında bu dört farklı tanı kriter sistemlerini geriye dönük olarak karşılaştırmayı amaçlamaktadır. Materyal ve Metod: Alerjik bronkopulmoner aspergilloz tanısı ile takip edilen hastalar geriye dönük olarak dört tanı kriter sistemi kullanılarak yeniden değerlendirildi ve bu kriterlerinin birbirlerine üstünlükleri araştırıldı. Bulgular: Toplam 10 ABPA hastası çalışmaya dahil edildi. Yedi hastaya ISHAM ABPA çalışma grubu tanı kriterlerine göre, altı hastaya Rosenberg-Patterson tanı kriterlerine göre tanı konuldu. ABPA-S ve ABPA-CB ile ayrı ayrı değerlendirildiğinde hiçbir hasta kriterleri karşılamadı. ISHAM tanısı konan hastaların beşinde total IgE seviyesi 1000 IU/mL’nin üzerinde ve ikisinde 1000 IU/mL’nin altındaydı. Sonuç: Sonuç olarak, ISHAM ABPA çalışma grubu tarafından oluşturulan tanı kriterlerinin, total Ig E 1000 IU/mL’nin üzerinde olan olgularda ABPA tanısı koymada diğer kriterlere göre daha üstün olduğu gösterilmiştir. Fakat radyolojik bulguları olanlarda total Ig E 1000 IU/mL’nin altında olan hastalarda minor kriterlerden olan Aspergillus fumigatus presipitan antikorlarının ya da spesifik IgG pozitifliğinin varlığının gerekliliğinin tartışılması ve çok daha geniş serilerle yapılacak çalışmalarla bu minor kriterlerin tekrar düzenlenmesi gerektiğini düşünüyoruz.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Türk M, ÇETİN g, Yilmaz I, nazik bahçecioğlu s (2022). The adequacy of current diagnostic criteria for making a diagnosis of ABPA. , 141 - 148. 10.5578/tt.20229804
Chicago	Türk Murat,ÇETİN gülden,Yilmaz Insu,nazik bahçecioğlu sakine The adequacy of current diagnostic criteria for making a diagnosis of ABPA. (2022): 141 - 148. 10.5578/tt.20229804
MLA	Türk Murat,ÇETİN gülden,Yilmaz Insu,nazik bahçecioğlu sakine The adequacy of current diagnostic criteria for making a diagnosis of ABPA. , 2022, ss.141 - 148. 10.5578/tt.20229804
AMA	Türk M,ÇETİN g,Yilmaz I,nazik bahçecioğlu s The adequacy of current diagnostic criteria for making a diagnosis of ABPA. . 2022; 141 - 148. 10.5578/tt.20229804
Vancouver	Türk M,ÇETİN g,Yilmaz I,nazik bahçecioğlu s The adequacy of current diagnostic criteria for making a diagnosis of ABPA. . 2022; 141 - 148. 10.5578/tt.20229804
IEEE	Türk M,ÇETİN g,Yilmaz I,nazik bahçecioğlu s "The adequacy of current diagnostic criteria for making a diagnosis of ABPA." , ss.141 - 148, 2022. 10.5578/tt.20229804
ISNAD	Türk, Murat vd. "The adequacy of current diagnostic criteria for making a diagnosis of ABPA". (2022), 141-148. https://doi.org/10.5578/tt.20229804

APA	Türk M, ÇETİN g, Yilmaz I, nazik bahçecioğlu s (2022). The adequacy of current diagnostic criteria for making a diagnosis of ABPA. Tüberküloz ve Toraks, 70(2), 141 - 148. 10.5578/tt.20229804
Chicago	Türk Murat,ÇETİN gülden,Yilmaz Insu,nazik bahçecioğlu sakine The adequacy of current diagnostic criteria for making a diagnosis of ABPA. Tüberküloz ve Toraks 70, no.2 (2022): 141 - 148. 10.5578/tt.20229804
MLA	Türk Murat,ÇETİN gülden,Yilmaz Insu,nazik bahçecioğlu sakine The adequacy of current diagnostic criteria for making a diagnosis of ABPA. Tüberküloz ve Toraks, vol.70, no.2, 2022, ss.141 - 148. 10.5578/tt.20229804
AMA	Türk M,ÇETİN g,Yilmaz I,nazik bahçecioğlu s The adequacy of current diagnostic criteria for making a diagnosis of ABPA. Tüberküloz ve Toraks. 2022; 70(2): 141 - 148. 10.5578/tt.20229804
Vancouver	Türk M,ÇETİN g,Yilmaz I,nazik bahçecioğlu s The adequacy of current diagnostic criteria for making a diagnosis of ABPA. Tüberküloz ve Toraks. 2022; 70(2): 141 - 148. 10.5578/tt.20229804
IEEE	Türk M,ÇETİN g,Yilmaz I,nazik bahçecioğlu s "The adequacy of current diagnostic criteria for making a diagnosis of ABPA." Tüberküloz ve Toraks, 70, ss.141 - 148, 2022. 10.5578/tt.20229804
ISNAD	Türk, Murat vd. "The adequacy of current diagnostic criteria for making a diagnosis of ABPA". Tüberküloz ve Toraks 70/2 (2022), 141-148. https://doi.org/10.5578/tt.20229804