Objective: Turkish Society of Nephrology registry collects data on hemodialysis, peritoneal dialysis, and transplantation annually. Registry reports are printed every year as a booklet, and this is the 31st year of registry reports. The registry is in close collaboration with international registries. Methods: In this paper, we summarized data from the 2020 registry report; additionally, we also provided yearly trends of managing end-stage kidney disease. Results: The number of patients on renal replacement therapy increases; at the end of 2020, 83 350 patients were on renal replacement therapy. The prevalence and incidence of end-stage renal disease were 996.8 and 138.7 per million population, respectively. Diabetes was the most common cause of end-stage renal disease. Hemodialysis (72.7%) was the most common type of treatment modality, followed by transplantation (23.3%) and peritoneal dialysis (4.06%). Conclusion: End-stage kidney disease is a critical and growing health problem for our country. The renal registry of the Turkish society of nephrology is one of the leading tools for providing current and sound data on this public health problem.