The Incidence of Composite Lymphomas: Case Studies Anddisease Management

Svetlana SMIRNOVA, (National Research Center for Hematology, Laboratory of Molecular Hematology, 4 Noviy Zykovskiy Proezd, Moscow, Russia)
Tatiana MOISEEVA, (National Research Center for Hematology, Consultative Hematology Department with a Day-Care Hospital, 4 Noviy Zykovskiy Proezd, Moscow, Russia)
Lubov AL-RADI, (National Research Center for Hematology, Consultative Hematology Department with a Day-Care Hospital, 4 Noviy Zykovskiy Proezd, Moscow, Russia)
Yulia SIDOROVA, (National Research Center for Hematology, Laboratory of Molecular Hematology, 4 Noviy Zykovskiy Proezd, Moscow, Russia)
Elena NIKULINA, (National Research Center for Hematology, Laboratory of Molecular Hematology, 4 Noviy Zykovskiy Proezd, Moscow, Russia)
Lubov PLASTININA, (National Research Center for Hematology, Consultative Hematology Department with a Day-Care Hospital, 4 Noviy Zykovskiy Proezd, Moscow, Russia)
Elena DOROHINA, (National Research Center for Hematology, Consultative Hematology Department with a Day-Care Hospital, 4 Noviy Zykovskiy Proezd, Moscow, Russia)
Bella BIDERMAN, (National Research Center for Hematology, Laboratory of Molecular Hematology, 4 Noviy Zykovskiy Proezd, Moscow, Russia)
Ekaterina ZAHARKO, (National Research Center for Hematology, Clinical laboratory, 4 Noviy Zykovskiy Proezd, Moscow, Russia)
Sergey KRAVCHENKO, (National Research Center for Hematology, Department of Intensive High-Dose Hemablastosis Chemotherapy, 4 Noviy Zykovskiy Proezd, Moscow, Russia)
Alla KOVRIGINA,
Andrey SUDARIKOV,
Eurasian Journal of Medicine and Oncology
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Yıl: 2022 Cilt: 6 Sayı: 2 Sayfa Aralığı: 130 - 136 Metin Dili: İngilizce DOI: 10.14744/ejmo.2022.14882 İndeks Tarihi: 06-07-2022

The Incidence of Composite Lymphomas: Case Studies Anddisease Management

Öz:
Objectives: Composite lymphomas (CL), which are a combination of different types of lymphomas in a single patient can occur simultaneously or sequentially. Diagnosis and treatment of CL require a full range of modern approaches. Methods: The study included 37 cases of CL (M:F=2:1), the median age of patients was 64 (38-83 years). All patients underwent a full range of diagnostic procedures, including histopathological, immunohistochemical/immunophenotypic (flow cytometry), cytogenetic/FISH, and molecular tests at the National Research Centre for Hematology, Moscow. Results: Metachronous CL were observed in 17 cases and the most common type of the second lymphoma was diffuse large B-cell lymphoma (DLBCL) or Hodgkin's lymphoma (HL). In 30% of cases, DLBCL developed after HL therapy, and in 30% - after therapy of angioimmunoblastic T-cell lymphoma (AITL). In 20 cases of synchronous CL the most common was B-cell chronic lymphocytic leukemia (B-CLL) combined with hairy cell leukemia (HCL) - 54.5%, large granular lymphocytic leukemia, marginal zone lymphoma (MZL), follicular lymphoma, multiple myeloma, or mycosis fungoides. A combination of HL with other lymphoma was observed in 25% of cases (HL+MZL represent 60% of cases). Conclusion: CL are excellent models for studying the complex process of tumor cells evolution during the course of the disease. Treatment of CL is a non-trivial task and aims to control both diseases.
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APA Smirnova S, Moiseeva T, Al-Radi L, Sidorova Y, Nikulina L, Plastinina L, Dorokhina E, Biderman B, ZAHARKO E, Kravchenko S, Kovrigina A, Sudarikov A (2022). The Incidence of Composite Lymphomas: Case Studies Anddisease Management. , 130 - 136. 10.14744/ejmo.2022.14882
Chicago Smirnova Svetlana,Moiseeva Tatiana N.,Al-Radi Liubov,Sidorova Yulia,Nikulina Lena,Plastinina Lyubov,Dorokhina E.I.,Biderman Bella,ZAHARKO Ekaterina,Kravchenko Sergey,Kovrigina Alla,Sudarikov Andrey The Incidence of Composite Lymphomas: Case Studies Anddisease Management. (2022): 130 - 136. 10.14744/ejmo.2022.14882
MLA Smirnova Svetlana,Moiseeva Tatiana N.,Al-Radi Liubov,Sidorova Yulia,Nikulina Lena,Plastinina Lyubov,Dorokhina E.I.,Biderman Bella,ZAHARKO Ekaterina,Kravchenko Sergey,Kovrigina Alla,Sudarikov Andrey The Incidence of Composite Lymphomas: Case Studies Anddisease Management. , 2022, ss.130 - 136. 10.14744/ejmo.2022.14882
AMA Smirnova S,Moiseeva T,Al-Radi L,Sidorova Y,Nikulina L,Plastinina L,Dorokhina E,Biderman B,ZAHARKO E,Kravchenko S,Kovrigina A,Sudarikov A The Incidence of Composite Lymphomas: Case Studies Anddisease Management. . 2022; 130 - 136. 10.14744/ejmo.2022.14882
Vancouver Smirnova S,Moiseeva T,Al-Radi L,Sidorova Y,Nikulina L,Plastinina L,Dorokhina E,Biderman B,ZAHARKO E,Kravchenko S,Kovrigina A,Sudarikov A The Incidence of Composite Lymphomas: Case Studies Anddisease Management. . 2022; 130 - 136. 10.14744/ejmo.2022.14882
IEEE Smirnova S,Moiseeva T,Al-Radi L,Sidorova Y,Nikulina L,Plastinina L,Dorokhina E,Biderman B,ZAHARKO E,Kravchenko S,Kovrigina A,Sudarikov A "The Incidence of Composite Lymphomas: Case Studies Anddisease Management." , ss.130 - 136, 2022. 10.14744/ejmo.2022.14882
ISNAD Smirnova, Svetlana vd. "The Incidence of Composite Lymphomas: Case Studies Anddisease Management". (2022), 130-136. https://doi.org/10.14744/ejmo.2022.14882
APA Smirnova S, Moiseeva T, Al-Radi L, Sidorova Y, Nikulina L, Plastinina L, Dorokhina E, Biderman B, ZAHARKO E, Kravchenko S, Kovrigina A, Sudarikov A (2022). The Incidence of Composite Lymphomas: Case Studies Anddisease Management. Eurasian Journal of Medicine and Oncology, 6(2), 130 - 136. 10.14744/ejmo.2022.14882
Chicago Smirnova Svetlana,Moiseeva Tatiana N.,Al-Radi Liubov,Sidorova Yulia,Nikulina Lena,Plastinina Lyubov,Dorokhina E.I.,Biderman Bella,ZAHARKO Ekaterina,Kravchenko Sergey,Kovrigina Alla,Sudarikov Andrey The Incidence of Composite Lymphomas: Case Studies Anddisease Management. Eurasian Journal of Medicine and Oncology 6, no.2 (2022): 130 - 136. 10.14744/ejmo.2022.14882
MLA Smirnova Svetlana,Moiseeva Tatiana N.,Al-Radi Liubov,Sidorova Yulia,Nikulina Lena,Plastinina Lyubov,Dorokhina E.I.,Biderman Bella,ZAHARKO Ekaterina,Kravchenko Sergey,Kovrigina Alla,Sudarikov Andrey The Incidence of Composite Lymphomas: Case Studies Anddisease Management. Eurasian Journal of Medicine and Oncology, vol.6, no.2, 2022, ss.130 - 136. 10.14744/ejmo.2022.14882
AMA Smirnova S,Moiseeva T,Al-Radi L,Sidorova Y,Nikulina L,Plastinina L,Dorokhina E,Biderman B,ZAHARKO E,Kravchenko S,Kovrigina A,Sudarikov A The Incidence of Composite Lymphomas: Case Studies Anddisease Management. Eurasian Journal of Medicine and Oncology. 2022; 6(2): 130 - 136. 10.14744/ejmo.2022.14882
Vancouver Smirnova S,Moiseeva T,Al-Radi L,Sidorova Y,Nikulina L,Plastinina L,Dorokhina E,Biderman B,ZAHARKO E,Kravchenko S,Kovrigina A,Sudarikov A The Incidence of Composite Lymphomas: Case Studies Anddisease Management. Eurasian Journal of Medicine and Oncology. 2022; 6(2): 130 - 136. 10.14744/ejmo.2022.14882
IEEE Smirnova S,Moiseeva T,Al-Radi L,Sidorova Y,Nikulina L,Plastinina L,Dorokhina E,Biderman B,ZAHARKO E,Kravchenko S,Kovrigina A,Sudarikov A "The Incidence of Composite Lymphomas: Case Studies Anddisease Management." Eurasian Journal of Medicine and Oncology, 6, ss.130 - 136, 2022. 10.14744/ejmo.2022.14882
ISNAD Smirnova, Svetlana vd. "The Incidence of Composite Lymphomas: Case Studies Anddisease Management". Eurasian Journal of Medicine and Oncology 6/2 (2022), 130-136. https://doi.org/10.14744/ejmo.2022.14882
Sayfa Oluşturulma Tarihi
23-04-2024 23:51

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