TY  - JOUR
TI  - Correlation Between Frozen Section and
Definitive Diagnosis in High-Risk Endometrial Carcinoma:
Retrospective Analysis
AB  - ABSTRACT Objective: This study aims to evaluate the correlation of intraoperative and definitive diagnosis in high-risk endometrial car-
cinomas, and percentages of compliance or non-compliance of intraoperative examination in high-risk endometrial carcinoma cases. Mate-
rial and Methods: In this retrospective study, the pathology archives of our center were evaluated and 90 high risk endometrial carcinoma
cases that were examined intraoperatively, between 2005-2017 were analyzed. The following criteria were used to identify high-risk en-
dometrial carcinoma cases: Grade 3 endometrioid carcinomas with lymphovascular invasion and/or myometrial invasion of more than half,
tumors of stage 2, 3, 4 and non-endometrioid endometrial carcinoma. Results: Histopathological subtyping was accurate in 52 of the 57 cases
of endometrioid carcinoma, 3 of the 20 cases of serous carcinoma and 1 of the 4 cases of clear cell carcinoma. None of the patients diagnosed
with mixed carcinoma were accurately diagnosed in frozen section. When results of intraoperative and permenant evaluations were com-
pared; 74.4% of the cases were compatible for histopathological subtype, 76.7% for grade, and 77.7% for myometrial invasion. Conclusion:
In patients with high-risk endometrial carcinoma without a preoperative diagnosis, intraoperative evaluation is essential for determining prog-
nostic parameters and performing surgical staging intraoperatively. Despite the careful evaluation of pathologists, the error rate is high in in-
traoperative evaluation of high-risk endometrial carcinomas. In order to minimize the error rate, both gross and microscopical assessment
should be performed with utmost care.
AU  - Oz Atalay, Fatma
AU  - YİRMİBEŞ, SELİN
AU  - özşen, mine
DO  - 10.5336/jcog.2021-85756
PY  - 2022
JO  - Journal of Clinical Obstetrics & Gynecology
VL  - 32
IS  - 2
SN  - 2619-9467
SP  - 39
EP  - 45
DB  - TRDizin
UR  - http://search/yayin/detay/532407
ER  -