TY  - JOUR
TI  - Decision-making based on International Society of Urological Pathology Gleason-scores obtained from transrectal needle biopsy of the Prostate: How Accurate Could We Be ?
AB  - Objective: The decision about the treatment of localized prostate cancer (PC) depends mainly on the histopathological results of transrectal needle biopsy. The agreement between the results of transrectal needle biopsies and radical prostatectomy specimens were reported to be varying. In this study, we aimed to investigate one institution’s homogenous repertory. A fair agreement could be revealed, and probable strategies to improve the rate of agreement are discussed.

Materials and Methods: 230 eligible patients who underwent radical prostatectomy (RP) and transrectal ultrasound guided prostate biopsy (TRUS-Bx)in our instutition were included in the study. Demographic characteristics, PSA levels (ng/ml) prior to TRUS-Bx, International Society of Urological Pathology (ISUP) Gleason groupgrades obtained from TRUS-Bx and RP were recorded and evaluated for concordance.

Results:137 of 250 patients RP pathology ISUP Gleason grades were compatible with TRUS-Bx pathology results (%59,6). 20 of 125 (%16) patients who reported to be ISUP Gleason grade 2 or 3 or 4 or 5 in initial biopsy found to be downgraded and 42 of 147 patients (29%), reported to have ISUP Gleason grade 1 upgraded in the final pathology.

Conclusion: In the diagnosis of PC, TRUS-Bx is an insufficient method to show the correct ISUP Gleason grade in radical prostatectomy specimen pathology.
AU  - KAZAZ, İLKE ONUR
DO  - 10.34087/cbusbed.961364
PY  - 2022
JO  - Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi
VL  - 9
IS  - 1
SN  - 2147-9607
SP  - 159
EP  - 163
DB  - TRDizin
UR  - http://search/yayin/detay/532893
ER  -