TY  - JOUR
TI  - Comparison of Pleth Variability Index and Inferior Vena Cava
Distensibility as a Perfusion Indicator in Sepsis Patients:
An Observational Study
AB  - ABSTRACT Objective: The aim of this study was to compare the sensitivity
and specificity of Pleth Variability Index (PVI) and distensibility of inferior
vena cava (dIVC) in fluid responsiveness of patients with sepsis. Material and
Methods: Forty patients over 18 years of age who underwent fluid replacement
for sepsis in the intensive care unit were included in the study. In our
study, the patients were divided into 2 groups as those who had less than 15%
increase in cardiac output (CO), and those who had more than 15% increase in
CO after fluid replacement (fluid responders and non-responders). Before fluid
replacement, demographic data of the patients (age, weight, cause of sepsis,
body surface area, SOFA score), vital parameters (systolic arterial pressure, diastolic
arterial pressure, mean arterial pressue, heart rate) and measuredd values
(maximum diameter of vena cava inferior, minimum diameter of vena cava
inferior, central venous pressure, PVI, CO, and stroke volume) were recorded.
After applying crystalloid in a dose of 10 mL/kg for 15 minutes, the recorded
parameters were repeated at 15th minute. Results: When receiver operating
characteristic (ROC) analysis was performed for dIVC, the area under the curve
(AUC) was found to be 0.833 (0.739-0.926). The threshold value was found to
be 17.52%, sensitivity was 77.5%, and specificity was 72.5%. When ROC analysis
was performed for PVI, AUC was found to be 0.889 (0.817-0.962). The
threshold value was found as 12.50%, sensitivity was 72.5%, and specificity
was 92.5%. Conclusion: PVI was found to be more specific but less sensitive
than dIVC. dIVC is less sensitive and less specific than central venous pressure.
However, dIVC and PVI can give useful results in patients who have contraindication
of an invasive technique.
AU  - Göktürk, Orhan
AU  - Avcı, Onur
AU  - Isbir, Ahmet Cemil
AU  - ÖZDEMİR KOL, İCLAL
AU  - KAYGUSUZ, KENAN
AU  - Gündoğdu, Oğuz
AU  - GÜRSOY, SİNAN
DO  - 10.5336/medsci.2021-85651
PY  - 2022
JO  - Türkiye Klinikleri Tıp Bilimleri Dergisi
VL  - 42
IS  - 2
SN  - 1300-0292
SP  - 79
EP  - 86
DB  - TRDizin
UR  - http://search/yayin/detay/532976
ER  -