Antibiotic Stewardship Program Experience in a Training
and Research Hospital

dalgıç, nazan; aktaş, elif; Eksi-Alp, Emel; Akgün, Cem; oncul, ahsen; Bayraktar, Banu

doi:10.14744/SEMB.2020.96337

Antibiotic Stewardship Program Experience in a Training and Research Hospital

Emel EKSİ ALP, (İstanbul Sağlık Bilimleri Üniversitesi Şişli Hamidiye Etfal Eğitim ve Araştırma Hastanesi Çocuk Acil Servisi, İstanbul, Türkiye)

Ahsen ÖNCÜL, (İstanbul Sağlık Bilimleri Üniversitesi Şişli Hamidiye Etfal Eğitim ve Araştırma Hastanesi Enfeksiyon Hastalıkları Anabilim Dalı, İstanbul, Türkiye)

Nazan DALGIÇ, (İstanbul Sağlık Bilimleri Üniversitesi Şişli Hamidiye Etfal Eğitim ve Araştırma Hastanesi Çocuk Enfeksiyon Hastalıkları Anabilim Dalı, İstanbul, Türkiye)

Cem AKGÜN, (İstanbul Sağlık Bilimleri Üniversitesi, Şişli Hamidiye Etfal Eğitim ve Araştırma Hastanesi, Beyin Cerrahisi Anabilim Dalı, İstanbul, Türkiye)

Elif AKTAŞ, (İstanbul Sağlık Bilimleri Üniversitesi, Şişli Hamidiye Etfal Eğitim ve Araştırma Hastanesi, Mikrobiyoloji Anabilim Dalı, İstanbul, Türkiye)

Banu BAYRAKTAR (İstanbul Sağlık Bilimleri Üniversitesi, Şişli Hamidiye Etfal Eğitim ve Araştırma Hastanesi, Mikrobiyoloji Anabilim Dalı, İstanbul, Türkiye)

Şişli Etfal Hastanesi Tıp Bülteni

2 1

Yıl: 2021 Cilt: 55 Sayı: 2 Sayfa Aralığı: 253 - 261 Metin Dili: İngilizce DOI: 10.14744/SEMB.2020.96337 İndeks Tarihi: 11-07-2022

Antibiotic Stewardship Program Experience in a Training and Research Hospital

Öz:

Objectives: Antibiotic Stewardship Programs (ASP) have been developed for the spread of rational antibiotic use. Our hospital is one of the first centers where ASP applications were launched in Turkey. In this study, we aimed to share our experience with ASP which has been applied in our hospital since 2013. Methods: We adapted ASP to our hospital program from Centers for Disease Control and Prevention’s ASP checklist. Revisions on surgical prophylaxis guidelines and practices were performed. Surgical prophylaxis was evaluated from hospital infection surveillance and antibiotic usage by point prevalence surveys. Antibiotic consumption indexes (ACI) were calculated from hospital pharmacy records. Rapid antigen detection test (RADT) for Group A beta-hemolytic streptococcus and influenza rapid antigen test were started to be used. Cumulative antibiotic susceptibility results were prepared annually. Results: Surgical prophylaxis was started to be administered in the operating room within 60 min of incision. Third-generation cephalosporin usage for surgical prophylaxis could be restricted in all clinics but the duration could only be shortened in neurosurgery and general surgery. There was no statistically significant change in antibiotic usage rates and appropriateness between 2014 and 2018. ACI for the class J01 in adult wards was 80.5 daily defined doses (DDD) per 100 patient days in 2014 and reduced to 64.8 DDD per 100 patient days in 2018. 22.445 pediatric patients presenting with complaints of the upper respiratory tract were evaluated with RADT and 75.1% were treated without antibiotics. Conclusion: In this global antimicrobial resistance era, all hospitals should have motivated antimicrobial stewardship teams. Each hospital should establish its own stewardship program and often revise it. Improvement in rational antibiotic use is hard to achieve without multidisciplinary involvement.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Eksi-Alp E, oncul a, dalgıç n, Akgün C, aktaş e, Bayraktar B (2021). Antibiotic Stewardship Program Experience in a Training and Research Hospital. , 253 - 261. 10.14744/SEMB.2020.96337
Chicago	Eksi-Alp Emel,oncul ahsen,dalgıç nazan,Akgün Cem,aktaş elif,Bayraktar Banu Antibiotic Stewardship Program Experience in a Training and Research Hospital. (2021): 253 - 261. 10.14744/SEMB.2020.96337
MLA	Eksi-Alp Emel,oncul ahsen,dalgıç nazan,Akgün Cem,aktaş elif,Bayraktar Banu Antibiotic Stewardship Program Experience in a Training and Research Hospital. , 2021, ss.253 - 261. 10.14744/SEMB.2020.96337
AMA	Eksi-Alp E,oncul a,dalgıç n,Akgün C,aktaş e,Bayraktar B Antibiotic Stewardship Program Experience in a Training and Research Hospital. . 2021; 253 - 261. 10.14744/SEMB.2020.96337
Vancouver	Eksi-Alp E,oncul a,dalgıç n,Akgün C,aktaş e,Bayraktar B Antibiotic Stewardship Program Experience in a Training and Research Hospital. . 2021; 253 - 261. 10.14744/SEMB.2020.96337
IEEE	Eksi-Alp E,oncul a,dalgıç n,Akgün C,aktaş e,Bayraktar B "Antibiotic Stewardship Program Experience in a Training and Research Hospital." , ss.253 - 261, 2021. 10.14744/SEMB.2020.96337
ISNAD	Eksi-Alp, Emel vd. "Antibiotic Stewardship Program Experience in a Training and Research Hospital". (2021), 253-261. https://doi.org/10.14744/SEMB.2020.96337

APA	Eksi-Alp E, oncul a, dalgıç n, Akgün C, aktaş e, Bayraktar B (2021). Antibiotic Stewardship Program Experience in a Training and Research Hospital. Şişli Etfal Hastanesi Tıp Bülteni, 55(2), 253 - 261. 10.14744/SEMB.2020.96337
Chicago	Eksi-Alp Emel,oncul ahsen,dalgıç nazan,Akgün Cem,aktaş elif,Bayraktar Banu Antibiotic Stewardship Program Experience in a Training and Research Hospital. Şişli Etfal Hastanesi Tıp Bülteni 55, no.2 (2021): 253 - 261. 10.14744/SEMB.2020.96337
MLA	Eksi-Alp Emel,oncul ahsen,dalgıç nazan,Akgün Cem,aktaş elif,Bayraktar Banu Antibiotic Stewardship Program Experience in a Training and Research Hospital. Şişli Etfal Hastanesi Tıp Bülteni, vol.55, no.2, 2021, ss.253 - 261. 10.14744/SEMB.2020.96337
AMA	Eksi-Alp E,oncul a,dalgıç n,Akgün C,aktaş e,Bayraktar B Antibiotic Stewardship Program Experience in a Training and Research Hospital. Şişli Etfal Hastanesi Tıp Bülteni. 2021; 55(2): 253 - 261. 10.14744/SEMB.2020.96337
Vancouver	Eksi-Alp E,oncul a,dalgıç n,Akgün C,aktaş e,Bayraktar B Antibiotic Stewardship Program Experience in a Training and Research Hospital. Şişli Etfal Hastanesi Tıp Bülteni. 2021; 55(2): 253 - 261. 10.14744/SEMB.2020.96337
IEEE	Eksi-Alp E,oncul a,dalgıç n,Akgün C,aktaş e,Bayraktar B "Antibiotic Stewardship Program Experience in a Training and Research Hospital." Şişli Etfal Hastanesi Tıp Bülteni, 55, ss.253 - 261, 2021. 10.14744/SEMB.2020.96337
ISNAD	Eksi-Alp, Emel vd. "Antibiotic Stewardship Program Experience in a Training and Research Hospital". Şişli Etfal Hastanesi Tıp Bülteni 55/2 (2021), 253-261. https://doi.org/10.14744/SEMB.2020.96337