HOW DO HYPERTRIGLYCERIDEMIA AND HYPOTRIGLYCERIDEMIA AFFECT PROGNOSIS IN ACUTE
ISCHEMIC STROKE AND WHAT IS THEIR PREVALENCE?

LEVENT, HAFİZE; Sorgun, Mine Hayriye; Taban, Elif Fatma; Rzayev, Sefer; KUZU KUMCU, MÜGE; rawandi, anwar; Ulukan, Çağrı; Yılmaz, Volkan; Ozer, Inci Sule; Tezcan Aydemir, Sabiha; TOGAY ISIKAY, CANAN; kuzu, zeynep

doi:10.5505/tbdhd.2021.23590

HOW DO HYPERTRIGLYCERIDEMIA AND HYPOTRIGLYCERIDEMIA AFFECT PROGNOSIS IN ACUTE ISCHEMIC STROKE AND WHAT IS THEIR PREVALENCE?

Zeynep ZIROĞLU, (Ankara Eğitim ve Araştırma Hastanesi, Nöroloji Anabilim Dalı, Ankara, Türkiye)

Mine Hayriye SORGUN, (Ankara Üniversitesi, Tıp Fakültesi, Nöroloji Anabilim Dalı, Ankara, Türkiye)

Elif Fatma TABAN, (Ankara Üniversitesi, Tıp Fakültesi, Nöroloji Anabilim Dalı, Ankara, Türkiye)

Sabiha TEZCAN AYDEMİR, (Ankara Üniversitesi, Tıp Fakültesi, Nöroloji Anabilim Dalı, Ankara, Türkiye)

Hafize ÇOTUR LEVENT, (Ankara Üniversitesi, Tıp Fakültesi, Nöroloji Anabilim Dalı, Ankara, Türkiye)

Çağrı ULUKAN, (Ankara Üniversitesi, Tıp Fakültesi, Nöroloji Anabilim Dalı, Ankara, Türkiye)

Sefer RZAYEV, (Ankara Üniversitesi, Tıp Fakültesi, Nöroloji Anabilim Dalı, Ankara, Türkiye)

Müge KUZU KUMCU, (Ankara Üniversitesi, Tıp Fakültesi, Nöroloji Anabilim Dalı, Ankara, Türkiye)

Volkan YILMAZ, (Ankara Üniversitesi, Tıp Fakültesi, Nöroloji Anabilim Dalı, Ankara, Türkiye)

İnci Şule ÖZER, (Ankara Üniversitesi, Tıp Fakültesi, Nöroloji Anabilim Dalı, Ankara, Türkiye)

Anwar RAWANDİ, (Ankara Üniversitesi, Tıp Fakültesi, Nöroloji Anabilim Dalı, Ankara, Türkiye)

Canan TOGAY IŞIKAY, (Ankara Üniversitesi, Tıp Fakültesi, Nöroloji Anabilim Dalı, Ankara, Türkiye)

Diğer Yazarlar

Türk Beyin Damar Hastalıkları Dergisi

6 1

Yıl: 2021 Cilt: 27 Sayı: 3 Sayfa Aralığı: 191 - 199 Metin Dili: İngilizce DOI: 10.5505/tbdhd.2021.23590 İndeks Tarihi: 12-07-2022

HOW DO HYPERTRIGLYCERIDEMIA AND HYPOTRIGLYCERIDEMIA AFFECT PROGNOSIS IN ACUTE ISCHEMIC STROKE AND WHAT IS THEIR PREVALENCE?

Öz:

INTRODUCTION: Many studies are examining the relationship between cardiovascular diseases and triglyceride levels, and it has been shown that hypertriglyceridemia significantly increases the risk independently. In this study, we wanted to investigate whether there is a similar relationship for stroke. METHODS: A total of 619 patients hospitalized with a diagnosis of acute ischemic stroke in our stroke center were included in the study. Demographic information, accompanying risk factors, hemoglobin level, thrombocyte count, triglyceride level, and C reactive protein level at the time of admission, and the National Institutes of Health Stroke Scale (NIHSS) scores in the first evaluation were recorded. Also, information about mortality in hospital, recurrent stroke, and the modified Rankin Scale (mRS) scores in the follow-up period was entered in our local database. RESULTS: While 182 patients (32.3%) (78 females (42.9%) and 104 males (57.1%); mean age 64.5±12.01 years) were diagnosed with hypertriglyceridemia, this number was 25 (4.4%) patients (13 females (52%) and 12 males (48%); mean age 70.9±17.4 years) for hypotriglyceridemia. Among the risk factors studied, only diabetes mellitus was found to be associated with hypertriglyceridemia in patients with acute ischemic stroke (P<0.05). DISCUSSION AND CONCLUSION: In this study conducted in our stroke center, hypertriglyceridemia and hypotriglyceridemia prevalences were found as 32.3% and 4.4%, respectively. HyperTG or hypoTG did not significantly affect on stroke severity and prognosis. We found out that DM is the major risk factor for acute ischemic stroke patients with hyperTG.

Anahtar Kelime:

İPERTRİGLİSERİDEMİ VE HİPOTRİGLİSERİDEMİ AKUT İSKEMİK İNMEDE PROGNOZU NASIL ETKİLER VE PREVALANSI NEDİR?

Öz:

GİRİŞ VE AMAÇ: Kardiyovasküler hastalıkların trigliserid düzeyi ile ilişkisini araştıran bir çok çalışma mevcuttur ve hipertrigliserideminin riski bağımsız olarak belirgin düzeyde artırdığı gösterilmiştir. Biz bu çalışmada benzer bir ilişkinin inme için var olup olmadığını göstermek istedik. GEREÇ VE YÖNTEM: Akut iskemik inmeli 619 hastanın verileri değerlendirildi. Demografik veriler, risk faktörleri, başvuru sırasındaki hemoglobin düzeyi, trombosit sayısı ve C reaktif protein düzeyi ve ilk değerlendirmedeki NIH İnme Ölçeği (National Institutes of Health Stroke Scale) puanları kayıt altına alındı. Ayrıca hastanede ölüm, tekrarlayan inme ve takiplerdeki modifiye Rankin Ölçeği (mRS) puanları veritabanına kayıt edildi. BULGULAR: Toplamda 182 hastanın (32.3%) (104 erkek (57.1%) ve 78 kadın (42.9%); ortalama yaş 64.5 ± 12.01 yıl) hipertrigliseridemisi vardı. Diğer yandan ise 25 hastanın (4.4%) (12 erkek (48%) ve 13 kadın (52%); ortalama yaş 70.9± 17.4 years) verileri hipotrigliseridemi ile uyumlu idi. Logistik regresyon analizinde sadece diabetes mellitus (DM) akut iskemik inmeli hastalardaki hipertrigliseridemi durumu ile belirgin ilişkili bulundu (P<0.05). TARTIŞMA VE SONUÇLAR: Hipertrigliseridemi bizim merkezimizde akut iskemik inmelerin 32.3% sinde görüldü. Diğer taraftan hipotrigliseridemi için bu oran 4.4% olarak saptandı. Hipertrigliseridemi veya hipotrigliserideminin olmasının inme şiddeti ve prognozuna etkisi olmadığı görüldü. Edinilen bilgiler ışığında hipertrigliseridemisi olan akut iskemik inmeli olgularda DM major risk faktörü gibi görünmektedir.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	kuzu z, Sorgun M, Taban E, Tezcan Aydemir S, LEVENT H, Ulukan Ç, Rzayev S, KUZU KUMCU M, Yılmaz V, Ozer I, rawandi a, TOGAY ISIKAY C (2021). HOW DO HYPERTRIGLYCERIDEMIA AND HYPOTRIGLYCERIDEMIA AFFECT PROGNOSIS IN ACUTE ISCHEMIC STROKE AND WHAT IS THEIR PREVALENCE?. , 191 - 199. 10.5505/tbdhd.2021.23590
Chicago	kuzu zeynep,Sorgun Mine Hayriye,Taban Elif Fatma,Tezcan Aydemir Sabiha,LEVENT HAFİZE,Ulukan Çağrı,Rzayev Sefer,KUZU KUMCU MÜGE,Yılmaz Volkan,Ozer Inci Sule,rawandi anwar,TOGAY ISIKAY CANAN HOW DO HYPERTRIGLYCERIDEMIA AND HYPOTRIGLYCERIDEMIA AFFECT PROGNOSIS IN ACUTE ISCHEMIC STROKE AND WHAT IS THEIR PREVALENCE?. (2021): 191 - 199. 10.5505/tbdhd.2021.23590
MLA	kuzu zeynep,Sorgun Mine Hayriye,Taban Elif Fatma,Tezcan Aydemir Sabiha,LEVENT HAFİZE,Ulukan Çağrı,Rzayev Sefer,KUZU KUMCU MÜGE,Yılmaz Volkan,Ozer Inci Sule,rawandi anwar,TOGAY ISIKAY CANAN HOW DO HYPERTRIGLYCERIDEMIA AND HYPOTRIGLYCERIDEMIA AFFECT PROGNOSIS IN ACUTE ISCHEMIC STROKE AND WHAT IS THEIR PREVALENCE?. , 2021, ss.191 - 199. 10.5505/tbdhd.2021.23590
AMA	kuzu z,Sorgun M,Taban E,Tezcan Aydemir S,LEVENT H,Ulukan Ç,Rzayev S,KUZU KUMCU M,Yılmaz V,Ozer I,rawandi a,TOGAY ISIKAY C HOW DO HYPERTRIGLYCERIDEMIA AND HYPOTRIGLYCERIDEMIA AFFECT PROGNOSIS IN ACUTE ISCHEMIC STROKE AND WHAT IS THEIR PREVALENCE?. . 2021; 191 - 199. 10.5505/tbdhd.2021.23590
Vancouver	kuzu z,Sorgun M,Taban E,Tezcan Aydemir S,LEVENT H,Ulukan Ç,Rzayev S,KUZU KUMCU M,Yılmaz V,Ozer I,rawandi a,TOGAY ISIKAY C HOW DO HYPERTRIGLYCERIDEMIA AND HYPOTRIGLYCERIDEMIA AFFECT PROGNOSIS IN ACUTE ISCHEMIC STROKE AND WHAT IS THEIR PREVALENCE?. . 2021; 191 - 199. 10.5505/tbdhd.2021.23590
IEEE	kuzu z,Sorgun M,Taban E,Tezcan Aydemir S,LEVENT H,Ulukan Ç,Rzayev S,KUZU KUMCU M,Yılmaz V,Ozer I,rawandi a,TOGAY ISIKAY C "HOW DO HYPERTRIGLYCERIDEMIA AND HYPOTRIGLYCERIDEMIA AFFECT PROGNOSIS IN ACUTE ISCHEMIC STROKE AND WHAT IS THEIR PREVALENCE?." , ss.191 - 199, 2021. 10.5505/tbdhd.2021.23590
ISNAD	kuzu, zeynep vd. "HOW DO HYPERTRIGLYCERIDEMIA AND HYPOTRIGLYCERIDEMIA AFFECT PROGNOSIS IN ACUTE ISCHEMIC STROKE AND WHAT IS THEIR PREVALENCE?". (2021), 191-199. https://doi.org/10.5505/tbdhd.2021.23590

APA	kuzu z, Sorgun M, Taban E, Tezcan Aydemir S, LEVENT H, Ulukan Ç, Rzayev S, KUZU KUMCU M, Yılmaz V, Ozer I, rawandi a, TOGAY ISIKAY C (2021). HOW DO HYPERTRIGLYCERIDEMIA AND HYPOTRIGLYCERIDEMIA AFFECT PROGNOSIS IN ACUTE ISCHEMIC STROKE AND WHAT IS THEIR PREVALENCE?. Türk Beyin Damar Hastalıkları Dergisi, 27(3), 191 - 199. 10.5505/tbdhd.2021.23590
Chicago	kuzu zeynep,Sorgun Mine Hayriye,Taban Elif Fatma,Tezcan Aydemir Sabiha,LEVENT HAFİZE,Ulukan Çağrı,Rzayev Sefer,KUZU KUMCU MÜGE,Yılmaz Volkan,Ozer Inci Sule,rawandi anwar,TOGAY ISIKAY CANAN HOW DO HYPERTRIGLYCERIDEMIA AND HYPOTRIGLYCERIDEMIA AFFECT PROGNOSIS IN ACUTE ISCHEMIC STROKE AND WHAT IS THEIR PREVALENCE?. Türk Beyin Damar Hastalıkları Dergisi 27, no.3 (2021): 191 - 199. 10.5505/tbdhd.2021.23590
MLA	kuzu zeynep,Sorgun Mine Hayriye,Taban Elif Fatma,Tezcan Aydemir Sabiha,LEVENT HAFİZE,Ulukan Çağrı,Rzayev Sefer,KUZU KUMCU MÜGE,Yılmaz Volkan,Ozer Inci Sule,rawandi anwar,TOGAY ISIKAY CANAN HOW DO HYPERTRIGLYCERIDEMIA AND HYPOTRIGLYCERIDEMIA AFFECT PROGNOSIS IN ACUTE ISCHEMIC STROKE AND WHAT IS THEIR PREVALENCE?. Türk Beyin Damar Hastalıkları Dergisi, vol.27, no.3, 2021, ss.191 - 199. 10.5505/tbdhd.2021.23590
AMA	kuzu z,Sorgun M,Taban E,Tezcan Aydemir S,LEVENT H,Ulukan Ç,Rzayev S,KUZU KUMCU M,Yılmaz V,Ozer I,rawandi a,TOGAY ISIKAY C HOW DO HYPERTRIGLYCERIDEMIA AND HYPOTRIGLYCERIDEMIA AFFECT PROGNOSIS IN ACUTE ISCHEMIC STROKE AND WHAT IS THEIR PREVALENCE?. Türk Beyin Damar Hastalıkları Dergisi. 2021; 27(3): 191 - 199. 10.5505/tbdhd.2021.23590
Vancouver	kuzu z,Sorgun M,Taban E,Tezcan Aydemir S,LEVENT H,Ulukan Ç,Rzayev S,KUZU KUMCU M,Yılmaz V,Ozer I,rawandi a,TOGAY ISIKAY C HOW DO HYPERTRIGLYCERIDEMIA AND HYPOTRIGLYCERIDEMIA AFFECT PROGNOSIS IN ACUTE ISCHEMIC STROKE AND WHAT IS THEIR PREVALENCE?. Türk Beyin Damar Hastalıkları Dergisi. 2021; 27(3): 191 - 199. 10.5505/tbdhd.2021.23590
IEEE	kuzu z,Sorgun M,Taban E,Tezcan Aydemir S,LEVENT H,Ulukan Ç,Rzayev S,KUZU KUMCU M,Yılmaz V,Ozer I,rawandi a,TOGAY ISIKAY C "HOW DO HYPERTRIGLYCERIDEMIA AND HYPOTRIGLYCERIDEMIA AFFECT PROGNOSIS IN ACUTE ISCHEMIC STROKE AND WHAT IS THEIR PREVALENCE?." Türk Beyin Damar Hastalıkları Dergisi, 27, ss.191 - 199, 2021. 10.5505/tbdhd.2021.23590
ISNAD	kuzu, zeynep vd. "HOW DO HYPERTRIGLYCERIDEMIA AND HYPOTRIGLYCERIDEMIA AFFECT PROGNOSIS IN ACUTE ISCHEMIC STROKE AND WHAT IS THEIR PREVALENCE?". Türk Beyin Damar Hastalıkları Dergisi 27/3 (2021), 191-199. https://doi.org/10.5505/tbdhd.2021.23590