BJECTIVE: This study was carried out to determine the sexual life quality of individuals over the age of 65 who were diagnosed with a chronic disease. MATERIAL AND METHODS: This descriptive and cross-sectional study was conducted with 100 female individuals aged 65 and over, married, without neuropsychiatric disease, and able to communicate verbally, hospitalized in the internal clinics of a University Training and Research Hospital between November 2021 and January 2022. Data in the research; It was collected using the Personal Information Form and the “Sexual Quality of Life Scale-Female”. RESULTS: Of the 100 individuals participating in the study, 57% were in the age group of 65–69, 56% were diagnosed with a chronic disease 10 years or less ago, the health status of 43% was neither good nor bad, 53% had a bad sexual life, 94% had a frequency of sexual intercourse longer than a month, 46% did not consult anyone about their sexual life problems, 72% did not have sexual desire. It was determined that 77% of them had a decrease in sexual intercourse, 77% of them had reluctance to have sexual intercourse, 14% of them had urinary incontinence, and 30% of them wanted to get information about sexual health. The mean score of women’s quality of sexual life was 62.20±6.10. The total sexual life quality scores of women who met and married happily, entered natural menopause, had sexual intercourse for more than two weeks, and had a secondary education level and above were significantly higher (p<0.05). CONCLUSION: It was determined that half of the women over the age of 65 with chronic diseases stated their sexual life as bad and their sexual life quality score were moderate. It was determined that nearly half of the individuals did not consult anyone about their sexual problems and their desire to get information about sexual health was low.